Abstract:Background
As one of the factors of male infertility, high temperature induces apoptosis of differentiated spermatogenic cells, sperm DNA oxidative damage, and changes in morphology and function of Sertoli cells. Spermatogonial stem cells (SSCs) is a kind of germline stem cells which maintain the spermatogenesis through self-renewal and differentiation. At present, however, the effect of high temperature on SSC differentiation in vitro has not been reported.
Methods
In the present study, we used in vitro dif… Show more
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