In this paper, the hot deformation behavior of a TNM TiAl-based alloy (Ti-44.45Al-3.80Nb-1.01Mo-0.29Si-0.14B) is investigated via isothermal compression tests. The experimental results demonstrate that the critical strain for dynamic recrystallization gradually decreases with increasing deformation temperature. At the initial stage of the low-temperature deformation process, the deformation is mainly caused by dislocation glide in the g and b phases. When the deformation reaches a certain level, dislocation glide in the b and the DRX g phases dominates the deformation. In the high-temperature deformation process, the deformation is the result of dislocation glide in the a and b phases.