High surface adsorption properties of carbon-based nanomaterials are responsible for mortality, swimming inhibition, and biochemical responses in Artemia salina larvae

Mesarič, Tina; Gambardella, Chiara; Milivojević, Tamara; Faimali, Marco; Drobne, Damjana; Falugi, Carla; Makovec, Darko; Jemec, Anita; Sepčić, Kristina

doi:10.1016/j.aquatox.2015.03.014

Cited by 87 publications

(43 citation statements)

References 42 publications

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“…Although to our knowledge no studies evaluated effects provoked in CAT and SOD enzymes in polychaetes after exposure to GO, recently Pretti et al (2014) showed that, graphene monolayer flakes up to the concentration of 1mg/L induced increased activity of CAT in Artemia salina after 48h exposure. On the other hand, Mesarič et al (2015) showed for the same species that exposure to carbon black, GO, and MWCNT after 48h did not induce significant differences in CAT activity at any of the tested concentrations. In the present study the activity of GSTs showed higher values at all GO exposure concentrations compared to control.…”

Section: Accepted Manuscriptmentioning

confidence: 88%

“…Although several authors already demonstrated that the regenerative capacity of D. neapolitana is affected by different stressors (pharmaceutical drugs (Freitas et al, 2015), organic matter (Carregosa et al, 2014), salinity and temperature (Pires et al, 2015)), the present study is the first revealing the impacts of GO on this physiological parameter in polychaetes. Nevertheless, previous studies showed that carbon based NMs induce alterations in physiological functions in invertebrate species (Wu et al, 2013;Mesarič et al, 2015). In the nematode Caenorhabditis elegans Wu et al (2013) examined the potential impacts of GO comparing in vivo effects between acute and chronic exposures, and found that prolonged exposure to 0.5-100 mg/L caused damage on functions of both primary (intestine), and secondary (neuron and reproductive organ) targeted organs.…”

Section: Discussionmentioning

confidence: 99%

“…sub-lethal effects at the digestion level with a possible less efficient intracellular digestive process. Mesarič et al (2015) investigated the effects of carbon black, GO, and multiwall carbon nanotubes on A. salina larvae for 48h, and showed that these nanomaterials were present in the gut, and attached onto the body surface of the organisms causing a concentration-dependent inhibition of larval swimming.…”

Section: Accepted Manuscriptmentioning

confidence: 99%

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Physiological and biochemical impacts of graphene oxide in polychaetes: The case of Diopatra neapolitana

Marchi

Neto

Pretti

et al. 2017

Comparative Biochemistry and Physiology Part C: Toxicology &

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Graphene oxide (GO) is an important carbon nanomaterial (NM) that has been used, but limited literature is available regarding the impacts induced in aquatic organisms by this pollutant and, in particular in invertebrate species. The polychaete Diopatra neapolitana has frequently been used to evaluate the effects of environmental disturbances in estuarine systems due to its ecological and socio-economic importance but to our knowledge no information is available on D. neapolitana physiological and biochemical alterations due to GO exposure. Thus, the present study aimed to assess the toxic effects of different concentrations of GO (0.01; 0.10 and 1.00mg/L) in D. neapolitana physiological (regenerative capacity) and biochemical (energy reserves, metabolic activity and oxidative stress related biomarkers) performance, after 28days of exposure. The results obtained revealed that the exposure to GO induced negative effects on the regenerative capacity of D. neapolitana, with organisms exposed to higher concentrations regenerating less segments and taking longer periods to completely regenerate. GO also seemed to alter energy-related responses, especially glycogen content, with higher values in polychaetes exposed to GO which may result from a decreased metabolism (measured by electron transport system activity), when exposed to GO. Furthermore, under GO contamination D. neapolitana presented cellular damage, despite higher activities of antioxidant and biotransformation enzymes in individuals exposed to GO.

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Section: Accepted Manuscriptmentioning

confidence: 88%

Section: Discussionmentioning

confidence: 99%

Section: Accepted Manuscriptmentioning

confidence: 99%

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Physiological and biochemical impacts of graphene oxide in polychaetes: The case of Diopatra neapolitana

Marchi

Neto

Pretti

et al. 2017

Comparative Biochemistry and Physiology Part C: Toxicology &

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“…Studies documenting GST involvement in signal transduction in nanomaterial toxicity are emerging (Klaper et al 2009;Zhao et al 2013). Current information on changes in GST activity patterns in graphene oxide-exposed invertebrates (Mesari c et al 2015;De Marchi et al 2017) is not sufficient to define the role of GST in graphene oxide toxicity. Our studies show no significant differences in GST activities in oysters exposed to graphene oxide.…”

Section: Biochemical Assessmentmentioning

confidence: 99%

A 72‐h exposure study with eastern oysters (Crassostrea virginica) and the nanomaterial graphene oxide

Khan

Adeleye

Burgess

et al. 2019

Enviro Toxic and Chemistry

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Graphene is a 2‐dimensional nanomaterial with unique mechanical, thermal, electrical, and optical properties. With increasing applications of graphene‐family nanomaterials (GFNs) in electronics, biomedicine, and surface coatings, concern for their impacts on aquatic ecosystems is rising. Current information on the toxicity of GFNs, including graphene oxide, is scarce. Filter‐feeding bivalves, such as eastern oysters, are good models for nanomaterial exposure studies. We present results from a 72‐h static renewal oyster study using 1 and 10 mg/L graphene oxide, which, to our knowledge, is the first report on in vivo effects of graphene oxide exposures in marine bivalves. Water samples were analyzed for graphene oxide concentration and size assessments. Gill and digestive gland tissues were evaluated for lipid peroxidation and glutathione‐S‐transferase (GST) activity. In addition, gill sections were fixed for histopathological analyses. Elevated lipid peroxidation was noted in oysters exposed to 10 mg/L graphene oxide. No significant changes in GST activity were observed, but reduced total protein levels were found in digestive gland tissues of exposed oysters at both concentrations. Loss of mucous cells, hemocytic infiltration, and vacuolation were observed in gills of exposed oysters. The results indicate that short‐term graphene oxide exposures can induce oxidative stress and epithelial inflammation and adversely affect overall oyster health. Further investigations regarding the fate and sublethal effects of graphene oxide are critical to understanding the risks associated with a rapidly growing graphene consumer market. Environ Toxicol Chem 2019;38:820–830. Published 2019 Wiley Periodicals Inc. on behalf of SETAC. This article is a US government work and, as such, is in the public domain in the United States of America.

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“…Tsarpalli and Nanomaterials. Mesaric et al, (2015) investigated the effects of three different carbon-based nanomaterials on brine shrimp (Artemia salina) larvae.…”

Section: Ionicmentioning

confidence: 99%

Effects of Pollution on Freshwater Organisms

Choudri

Baawain

2016

Water Environment Research

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This review includes works published in the general scientific literature during 2015 on the effects of anthropogenic pollutants on freshwater organisms. It begins with two broad sections: research reviews and broad field studies and surveys. This is followed by reviews of research categorized in sections to reflect the pollutant class. These sections include wastewater, stormwater and non-point source pollution, nutrients, sediment cap materials and suspended clays, botanical extracts, surfactants, metals, persistent organic pollutants, pharmaceuticals, endocrine disruptors, pesticides, petroleum hydrocarbons and polycyclic aromatic hydrocarbons (PAHs), ionic liquids, and nanomaterials. The final section includes works describing innovations in the field of freshwater pollution research.

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High surface adsorption properties of carbon-based nanomaterials are responsible for mortality, swimming inhibition, and biochemical responses in Artemia salina larvae

Cited by 87 publications

References 42 publications

Physiological and biochemical impacts of graphene oxide in polychaetes: The case of Diopatra neapolitana

Physiological and biochemical impacts of graphene oxide in polychaetes: The case of Diopatra neapolitana

A 72‐h exposure study with eastern oysters (Crassostrea virginica) and the nanomaterial graphene oxide

Effects of Pollution on Freshwater Organisms

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