High-stiffness, fast-crosslinking, cartilage matrix bioinks

Kiyotake, Emi A.; Thomas, Emily E.; Iribagiza, Claudia; Detamore, Michael S.

doi:10.1016/j.jbiomech.2023.111471

Cited by 4 publications

(2 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…There are various materials that are considered for use in in situ bioprinting, such as hydrogels based on Gallol-Functionalized Hyaluronic Acid [ 98 ], methacrylate-based gelatin [ 99 ], and bioinks based on alginate–chitosan and kaolin [ 100 ]. Current research focuses on in situ bioprinting applications for direct cartilage repair [ 101 , 102 ] or bioprinting human mesenchymal cells that will transdifferentiate into chondrogenic tissue [ 103 ]. In situ bioprinting may also be used for skin wound regeneration, providing accurate coverage of the affected area [ 104 ].…”

Section: 3d Cell Culturesmentioning

confidence: 99%

Biomimetic Scaffolds—A Novel Approach to Three Dimensional Cell Culture Techniques for Potential Implementation in Tissue Engineering

Górnicki,

Lambrinow,

Golkar-Narenji

et al. 2024

Nanomaterials

View full text Add to dashboard Cite

Biomimetic scaffolds imitate native tissue and can take a multidimensional form. They are biocompatible and can influence cellular metabolism, making them attractive bioengineering platforms. The use of biomimetic scaffolds adds complexity to traditional cell cultivation methods. The most commonly used technique involves cultivating cells on a flat surface in a two-dimensional format due to its simplicity. A three-dimensional (3D) format can provide a microenvironment for surrounding cells. There are two main techniques for obtaining 3D structures based on the presence of scaffolding. Scaffold-free techniques consist of spheroid technologies. Meanwhile, scaffold techniques contain organoids and all constructs that use various types of scaffolds, ranging from decellularized extracellular matrix (dECM) through hydrogels that are one of the most extensively studied forms of potential scaffolds for 3D culture up to 4D bioprinted biomaterials. 3D bioprinting is one of the most important techniques used to create biomimetic scaffolds. The versatility of this technique allows the use of many different types of inks, mainly hydrogels, as well as cells and inorganic substances. Increasing amounts of data provide evidence of vast potential of biomimetic scaffolds usage in tissue engineering and personalized medicine, with the main area of potential application being the regeneration of skin and musculoskeletal systems. Recent papers also indicate increasing amounts of in vivo tests of products based on biomimetic scaffolds, which further strengthen the importance of this branch of tissue engineering and emphasize the need for extensive research to provide safe for humansbiomimetic tissues and organs. In this review article, we provide a review of the recent advancements in the field of biomimetic scaffolds preceded by an overview of cell culture technologies that led to the development of biomimetic scaffold techniques as the most complex type of cell culture.

show abstract

Section: 3d Cell Culturesmentioning

confidence: 99%

Biomimetic Scaffolds—A Novel Approach to Three Dimensional Cell Culture Techniques for Potential Implementation in Tissue Engineering

Górnicki,

Lambrinow,

Golkar-Narenji

et al. 2024

Nanomaterials

View full text Add to dashboard Cite

show abstract

“…The ECM with the highest DOF (1.1 mmol/g) was not printable because of its high viscosity. More recently, they functionalized devitalized cartilage ECM using pentenoic anhydride to achieve faster photocrosslinking through thiol-ene click chemistry compared to their methacrylated ECM [40] .…”

Section: Preparing Tissue-derived Decm For Use In Bioinks and Bioresinsmentioning

confidence: 99%

Rise of tissue- and species-specific 3D bioprinting based on decellularized extracellular matrix-derived bioinks and bioresins

Elomaa,

Almalla,

Keshi

et al. 2023

Biomaterials and Biosystems

View full text Add to dashboard Cite

Alginate, hyaluronic acid, and chitosan-based 3D printing hydrogel for cartilage tissue regeneration

Jo Jang,

Patel,

Sankpal

et al. 2024

European Polymer Journal

View full text Add to dashboard Cite

High-stiffness, fast-crosslinking, cartilage matrix bioinks

Cited by 4 publications

References 29 publications

Biomimetic Scaffolds—A Novel Approach to Three Dimensional Cell Culture Techniques for Potential Implementation in Tissue Engineering

Biomimetic Scaffolds—A Novel Approach to Three Dimensional Cell Culture Techniques for Potential Implementation in Tissue Engineering

Rise of tissue- and species-specific 3D bioprinting based on decellularized extracellular matrix-derived bioinks and bioresins

Alginate, hyaluronic acid, and chitosan-based 3D printing hydrogel for cartilage tissue regeneration

Contact Info

Product

Resources

About