High-sodium maltobionate production by immobilized Zymomonas mobilis cells in polyurethane

Souza, Roberta Cristina de; Silva, Leonardo Meirelles da; Carra, Sabrina; Flores, Maicon; Puton, Bruna Maria Saorin; Malvessi, Eloane; Valduga, Eunice; Zeni, Jamile

doi:10.1007/s00449-022-02756-2

Cited by 4 publications

(1 citation statement)

References 26 publications

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“…Because of the high-value substrate, an alternative maltose source, such as high maltose syrup, was explored later. Immobilizing Z. mobilis cells in a matrix of polyurethane resulted in high product concentrations of up to 230 g L −1 of MBA with a yield of nearly 90% and a volumetric productivity of 6.75 g L −1 h −1 using the GFOR/GL complex [ 120 ]. The underlying catalytic mechanism of this enzyme complex was first described in 1986 for the conversion of its native substrates glucose and fructose to gluconic acid and sorbitol [ 121 ].…”

Section: Biological Production Methodsmentioning

confidence: 99%

Bioproduction and applications of aldobionic acids with a focus on maltobionic and cellobionic acid

Bieringer

Vázquez

Klein

et al. 2023

Bioprocess Biosyst Eng

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Aldobionic acids are sugar acids which consist of a disaccharide with an anomeric acid group. The most famous is lactobionic acid (LBA). LBA is used in many applications such as food and beverages, pharmaceuticals and medicine, cosmetics or chemical processes. During the last decade, all these industries are observing a shift of consumer preferences towards plant-based options. Thus, the biotechnological industry is trying to replace the animal-derived LBA. Maltobionic acid (MBA) and cellobionic acid (CBA) are two stereoisomers of LBA which have emerged as vegan alternatives. However, MBA and CBA face different obstacles related to their industrial production. While traditionally used electrochemical or chemical catalysis often rely on cost intensive and/or hazardous catalysts, novel production methods with microorganisms are still poorly studied. In the first part, this paper discusses both alternatives in terms of their characteristics and applications. In the second part, it reviews the long-studied chemical production and the novel bioproduction methods, which are based on enzymatic and microbial systems. This review concludes with a discussion of future work needed to bring their production to the industrial scale.

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Section: Biological Production Methodsmentioning

confidence: 99%