High Serum Levels of Ferritin May Predict Poor Survival and Walking Ability for Patients with Hip Fractures: A Propensity Score Matching Study

Abstract

Aim: To identify the relationship between ferritin and outcomes for patients with hip fractures. Patients & methods: All patients with hip fractures presenting between May 2017 and January 2021 were included. Univariate and multivariate analyses were performed to determine the risk factors for 1-year survival. Propensity score matching (PSM) was performed for groups divided by ferritin levels. Results: A total of 165 patients were included of whom 28 died during the first year after surgery. Ferritin levels differed significantly between groups divided by 1-year survival. High ferritin (≥308.5 ng/ml) was related to poor 1-year survival and 6-month and 1-year independent walking rate. Conclusion: High ferritin (≥308.5 ng/ml) may predict poor survival and free-walking abilities after surgery for patients with hip fractures.

Mapping knowledge structure and global status of sarcopenia in geriatric hip fractures: A bibliometric and visualized study

“…Many studies based on populations have suggested that patients with hip fractures treated with anti-osteoporosis medications may face an improved prognosis after surgery ( 29 , 30 ). However, many risk factors were also reported to be associated with the risk and prognosis of geriatric hip fractures, such as supplementation of vitamin D3 ( 31 ), the neutrophil-to-lymphocyte ratio ( 32 ), ferritin ( 33 ), and so on. Sarcopenia as an age-related and complex disease had attracted much attention in recent years ( 34 ).…”