2015
DOI: 10.1002/ajim.22470
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High‐sensitivity CRP: Possible link between job stress and atherosclerosis

Abstract: High effort, overcommmitment, and ERI were positively associated with hs-CRP. Inflammation indicated by hs-CRP may be one of important mediators linking job stress and atherosclerosis.

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Cited by 18 publications
(12 citation statements)
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References 37 publications
(50 reference statements)
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“…These variables are used as markers of potential psychobiological pathways mediating stressful experience with disease development. They include studies with experimental or cross-sectional design, where cardiovascular (six reports) [ 32 , 33 , 34 , 35 , 36 , 37 ], immune (three reports) [ 38 , 39 , 40 ] and hormonal parameters (seven reports) [ 32 , 41 , 42 , 43 , 44 , 45 , 46 ] were analyzed. As one report analyzed two different psychobiological markers [ 32 ] the number of studies presented in Table 1 is 27 instead of 28.…”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…These variables are used as markers of potential psychobiological pathways mediating stressful experience with disease development. They include studies with experimental or cross-sectional design, where cardiovascular (six reports) [ 32 , 33 , 34 , 35 , 36 , 37 ], immune (three reports) [ 38 , 39 , 40 ] and hormonal parameters (seven reports) [ 32 , 41 , 42 , 43 , 44 , 45 , 46 ] were analyzed. As one report analyzed two different psychobiological markers [ 32 ] the number of studies presented in Table 1 is 27 instead of 28.…”
Section: Resultsmentioning
confidence: 99%
“…Immune system-related variables analyzed in this context include natural killer (NK) cells, T helper cells, and C-reactive protein (CRP) as an inflammatory marker. Two reports found significant associations of OC with increased CRP [ 38 ] and with reduced NK cells respectively. In this latter study, a lower increase of T helper cells following stress was also observed in association with OC and to some extent with ERI [ 39 ].…”
Section: Resultsmentioning
confidence: 99%
“…Participants with high effort-reward imbalance exhibited a significantly stronger increase in CRP under acute laboratory stress compared to those with low levels of work stress [ 91 ]. In two cross-sectional studies, one conducted among 204 Jordanian men [ 69 ] and one conducted in 731 working men and women in China [ 92 ], CRP was significantly associated with ERI, and in China additionally with over-commitment. More recently, baseline screening data from a large cohort of working men and women in France ( N = 43,593) were analysed where high ERI was associated with higher white blood cell counts—a marker of increased low-grade systemic inflammation—both among men and women [ 93 ].…”
Section: Resultsmentioning
confidence: 99%
“…Previous studies indicate that a number of factors affect job stress, including depression (14-16), personality type (17, 18), physical activity (19, 20), socioeconomic status (17, 21, 22), job satisfaction (23, 24), and demographic variables like age, education, and marital status (1, 17, 24-26). Given the importance of job stress, especially in staff personnel, there is an urgent need to study all related factors simultaneously.…”
Section: Introductionmentioning
confidence: 99%