High Sensitivity Coreless Fiber Surface Plasmon Resonance Sensor Based on Au Nano Biconical Particles

Wang, Qi; Zhu, Aizhi; Qiu, Fengmei; Wang, Lei; Yin, Xiangyu; Zhao, Wan‐Ming; Du, Na-Na; Cong, Xue-Wei; Ren, Zi-Han; Hua, Lin-Rui; Zhang, Keke

doi:10.1109/jsen.2021.3121447

Cited by 10 publications

(6 citation statements)

References 46 publications

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“…The optical fiber needs to be pretreated before the experiment. The prepared structures were first soaked in 1% PDDA for 2 h. The surface of the PDDA-treated fiber was positively charged . The steps of lipase immobilization are listed in Figure .…”

Section: Methodsmentioning

confidence: 99%

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Optical Fiber Surface Plasmon Resonance Sensor for Glyceryl Tributyrate Detection Based on the PAA/CS Composite Hydrogel Embedding Protease Method

Zhang,

Li,

Zhou

et al. 2024

Anal. Chem.

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Glycerol tributyrate as a low-density lipoprotein plays a crucial role in drug development and food safety. In this work, a novel high-stability fiber optic sensor for glyceryl tributyrate based on the poly(acrylic acid) (PAA) and chitosan (CS) composite hydrogel embedding method is first proposed. Compared with traditional functionalization, the lipase in a polymer network structure used in this article can not only avoid chemical reactions that cause damage to the enzyme structure but also avoid the instability of ionic bonds and physical adsorption. Therefore, the PAA/CS hydrogel method proposed in this article can effectively retain enzyme structure. First, the impact of different layers (one to five layers) of PAA/CS on pH sensing performance was explored, and it was determined that layers 1−3 could be used for subsequent sensing experiments. Within the linear detection range of 0.5−10 mM, the detection sensitivities of the one to three layers of the biosensor are divided into 0.65, 0.95, and 1.51 nm/mM, respectively, with the three layers having the best effect. When the number of coating layers is three, the detection limit of the sensor is 0.47 mM, meeting the millimole level detection standard for anticancer requirement. Furthermore, the stability and selectivity of the sensor (in the presence of hemoglobin, urea, cholesterol, acetylcholine, and glucose) were analyzed. The three-layer sensor is used for sample detection. At concentrations of 1− 10 mM, the absolute value of the recovery percentage (%) is 82−99%, which can accurately detect samples. The sensor proposed in this paper has the advantages of low sample consumption, high sensitivity, simple structure, and label-free measurement. The enzyme-embedding method provides a new route for rapid and reliable glyceryl tributyrate detection, which has potential applications in food safety as well as the development of anticancer drugs.

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Section: Methodsmentioning

confidence: 99%

“…The prepared structures were first soaked in 1% PDDA for 2 h. The surface of the PDDA-treated fiber was positively charged. 31 The steps of lipase immobilization are listed in Figure 2. The fiber surface was rinsed with anhydrous ethanol and pure water, and the spectrum at this point was used as a reference.…”

Section: Lipase Immobilizationmentioning

confidence: 99%

Optical Fiber Surface Plasmon Resonance Sensor for Glyceryl Tributyrate Detection Based on the PAA/CS Composite Hydrogel Embedding Protease Method

Zhang,

Li,

Zhou

et al. 2024

Anal. Chem.

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“…This occurs when the sensing layer is under the influence of total internal reflection (TIR). The wavelength-dependent RI of TiO 2 can be expressed by Equation ( 3 ) [ 7 ].

Here,

is the operating wavelength.…”

Section: Numerical Analysismentioning

confidence: 99%

“…Sensing techniques based on Mach Zehnder interferometer, fiber grating, spectroscopy, and wavelength division multiplexing are the most demanding approaches. The optical light intensity has been used for prominent sensing techniques such as colorimetric [ 5 ], light scattering [ 6 ], surface plasmon resonance (SPR) sensors [ 7 ], scattering sensors [ 8 ], electrochemiluminescence sensors [ 9 ], fluorescent sensors [ 10 ], and so on. Various analyses were performed, and the relative sensitivity of 45% was noted for identifying hazardous chemicals that are harmful to the human body [ 11 ].…”

Section: Introductionmentioning

confidence: 99%

Au-TiO2-Coated Spectroscopy-Based Human Teeth Disorder Detection Sensor: Design and Quantitative Analysis

et al. 2023

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Human tooth functionality is the most important for the human body to become fit and healthy. Due to the disease attacks in human teeth, parts may lead to different fatal diseases. A spectroscopy-based photonic crystal fiber (PCF) sensor was simulated and numerically analyzed for the detection of dental disorders in the human body. In this sensor structure, SF11 is used as the base material, gold (Au) is used as the plasmonic material, and TiO2 is used within the gold and sensing analyte layer, and the sensing medium for the analysis of the teeth parts is the aqueous solution. The maximum optical parameter values for the human tooth parts enamel, dentine, and cementum in terms of wavelength sensitivity and confinement loss were obtained as 28,948.69 nm/RIU and 0.00015 dB/m for enamel, 33,684.99 nm/RIU and 0.00028 dB/m, and 38,396.56 nm/RIU and 0.00087 dB/m, respectively. The sensor is more precisely defined by these high responses. The PCF-based sensor for tooth disorder detection is a relatively recent development. Due to its design flexibility, robustness, and wide bandwidth, its application area has been spreading out. The offered sensor can be used in the biological sensing area to identify problems with human teeth.

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“…As a special type of optical fiber, coreless fibers exhibit unique transmission characteristics as the sensing part of the NCF is in direct contact with the external environment. In recent years, the NCF has been commonly coated with a metal film to excite surface plasmon resonance [24,25]. All these methods are precise and sensitive; however, in case of a high RI sensitivity, these methods are unable to simultaneously ensure the advantages of simple manufacturing, good robustness, and low cost.…”

Section: Introductionmentioning

confidence: 99%

Temperature-insensitive high sensitivity refractive index sensor based on tapered no core fiber

Lu¹,

Liu²,

Ren³

et al. 2023

Meas. Sci. Technol.

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This study fabricated an ultra-high refractive index sensor based on tapered no-core fiber involving a simple inexpensive process. A splice section of no-core fiber in the middle of single mode fiber was tapered to small diameters. The sensor was sensitive to the surrounding refractive index with a large measurement range of 1.3330–1.4437. The refractive index sensitivity differed with varying wavelengths, with a value of 41916 nm/RIU at approximately 1550 nm. It yielded a low temperature sensitivity of 8.1 pm/°C that can be ignored compared with the refractive index sensitivity. The proposed fiber optic refractive index sensor can be used in many fields such as medicine and biochemical applications.

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High Sensitivity Coreless Fiber Surface Plasmon Resonance Sensor Based on Au Nano Biconical Particles

Cited by 10 publications

References 46 publications

Optical Fiber Surface Plasmon Resonance Sensor for Glyceryl Tributyrate Detection Based on the PAA/CS Composite Hydrogel Embedding Protease Method

Optical Fiber Surface Plasmon Resonance Sensor for Glyceryl Tributyrate Detection Based on the PAA/CS Composite Hydrogel Embedding Protease Method

Au-TiO2-Coated Spectroscopy-Based Human Teeth Disorder Detection Sensor: Design and Quantitative Analysis

Temperature-insensitive high sensitivity refractive index sensor based on tapered no core fiber

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