High N6‐methyladenosine‐activated TCEAL8 mRNA is a novel pancreatic cancer marker
Tomoaki Hara,
Sikun Meng,
Hiromichi Sato
et al.
Abstract:N6‐methyladenosine (m6A) is an RNA modification involved in RNA processing and widely found in transcripts. In cancer cells, m6A is upregulated, contributing to their malignant transformation. In this study, we analyzed gene expression and m6A modification in cancer tissues, ducts, and acinar cells derived from pancreatic cancer patients using MeRIP‐seq. We found that dozens of RNAs highly modified by m6A were detected in cancer tissues compared with ducts and acinar cells. Among them, the m6A‐activated mRNA T… Show more
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