High Risk of Sensorineural Hearing Loss in Men Born Small for Gestational Age with and without Obesity or Height Catch-Up Growth: A Prospective Longitudinal Register Study on Birth Size in 245,000 Swedish Conscripts

Barrenäs, Marie-Louise; Jonsson, Björn; Tuvemo, Torsten; Hellström, Per‐Anders; Lundgren, Maria

doi:10.1210/jc.2005-0385

Cited by 52 publications

(61 citation statements)

References 24 publications

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“…Barrenas also demonstrated an association between overweight and obesity and sensori-neural hearing impairment (SNHI) especially if born light for gestational age. These results were broadly consistent with SNHI resulting from mechanisms suggested by the thrifty phenotype hypothesis, with SNHI as a possible clinical feature of the metabolic syndrome (Barrenas et al 2005b).…”

Section: Introductionsupporting

confidence: 87%

“…Fransen also found that taller people had, on average, better hearing, replicating a previous finding by Barrenas (Barrenas et al 2003(Barrenas et al , 2005a. In a separate study, Barrenas found an association between being born short or light for gestational age and higher hearing threshold levels at age 17-24yrs among Swedish male conscripts (Barrenas et al 2005b). Barrenas also demonstrated an association between overweight and obesity and sensori-neural hearing impairment (SNHI) especially if born light for gestational age.…”

Section: Introductionsupporting

confidence: 71%

“…Barrenas's large prospective longitudinal register study of 245,000 Swedish conscripts aged 17-24yrs, also demonstrated an association between current overweight/obesity and sensorineural hearing threshold (Barrenas et al 2005b) although no data were available on potential social and environmental confounders. Unlike Barrenas, we found no association between being light for gestational age at birth and hearing impairment in early adulthood.…”

Section: Comparison With Other Studiesmentioning

confidence: 99%

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BMI over the lifecourse and hearing ability at age 45 years: a population based study

Ecob¹,

Russ

Davis

2011

LLCS

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Section: Introductionsupporting

confidence: 87%

Section: Introductionsupporting

confidence: 71%

Section: Comparison With Other Studiesmentioning

confidence: 99%

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BMI over the lifecourse and hearing ability at age 45 years: a population based study

Ecob¹,

Russ

Davis

2011

LLCS

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“…It seems unlikely that an increased stature has a generalized adverse effect on the peripheral nerve function, since sensorineural hearing loss, another form of peripheral deficit, by contrast, is associated with a reduced stature (Barrenas et al,) [31]. A short stature is associated with CVS disease, hypertension, early arterial stiffening, IGT, type 2 DM, GDM and pre-eclampsia.…”

Section: Discussionmentioning

confidence: 99%

Peripheral Insensate Neuropathy- Is Height a Risk Factor?

Kote

Bhat²,

Thajuddeen

et al. 2013

JCDR

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Introduction: Peripheral insensate neuropathy is one of the most commonest and the earliest forms of peripheral neuropathy. It is one of the leading causes of the disability in working population who are at risk. Methods:A study was conducted in Kasturba medical college (Manipal university) in the year 2009-12, which included examination of 818 people of more than 30yrs of age by random sampling method who were attending the outpatient clinic. A monofilament was used to determine the peripheral insensate neuropathy, which was defined by the presence of one or more insensate areas. Results:In our study , the prevalence of peripheral insensate neuropathy was 16.2 % ( p-0.0001), among which 9.7% were males and 7.5% were females. The males were 1.27 times significantly at a higher risk than the females , even after a height adjustment to the gender difference in height. As the height increased, the prevalence of peripheral insensate neuropathy increased, irrespective of the diabetic and hypertensive statuses. The risk of the peripheral insensate neuropathy increases at a height of >167 cm in males and at a height of >159 cm in females. Conclusion:The authors conclude that body height is an important and an independent risk factor for peripheral insensate neuropathy, irrespective of co morbidities. Height as a marker, helps the health care professionals in identifying the people who are at risk for peripheral insensate neuropathy.G S Sharath Kote, ajay N Bhat, thajuddeeN K, MohaMMed h ISMaIl, aBhISheK Gupta InTROduCTIOnPeripheral insensate neuropathy is defined as the presence of one or more insensate areas [1]. It is a common problem which is encountered in middle and old aged people. It is one of the disabling complications of diabetes because of its high incidence and its potential to lead to lower extremity ulceration, deformation and amputation [2]. Many factors have been associated with neuropathy, like age, sex, race, glycaemic control, nutrition, toxin exposure, drugs, alcohol, etc [1,3,4].Peripheral neuropathy affects 2-8% of the adults and it increases with age. With an early detection and history taking and focused laboratory tests, the underlying cause can be identified in ~75% of the cases. The prevalence of neuropathy is 66% for type 1 diabetes and it is 59% for type 2 diabetes. In a population cohort of diabetic patients, two third of the diabetics had an objective evidence of neuropathy, mainly a loss of the foot sensation, but only 15% of the IDDM cases and 13% of the NIDDM cases were symptomatic. Peripheral neuropathy can occur before the onset of clinically detectable Diabetes mellitus (DM) [5].Height is an important and a practical predictor of peripheral insensate neuropathy. As the height increases, the lengths of the nerve fibers also increase and so the surface area of the axons is available for the toxin exposure and the physical damage is more. So, the risk of peripheral insensate neuropathy increases with an increase in height. Many studies have shown the corelation of height with p...

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“…Although prematurity and low birthweight are known to be associated with congenital hearing loss, the causal pathway has not been clearly delineated. One study in Atlanta showed elevated relative risks of bilateral sensorineural hearing impairment among children with lower birthweights: prevalence was 0.4/1000 in children weighing ≥4000 g, compared with 1.27/1000 for 1500-1499 g and 5.1/1000 for those <1500 g (Barrenas et al 2005b) and in males of short stature (Barrenas et al 2005a). This interesting finding has led to the hypothesis that fetal programming arising from intrauterine growth retardation might result in delayed cell cycles during development of the cochlea which eventually leads to development of SNHL in adulthood (Niskar et al 2001).…”

Section: Environmental Causes Of Hearing Lossmentioning

confidence: 99%

A Life Course Approach to Hearing Health

Russ¹,

Tremblay

Halfon

et al. 2017

Handbook of Life Course Health Development

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Challenges to hearing health are a significant public health problem. At least ten million Americans have a hearing loss that interferes with the understanding of normal speech. If lesser degrees of loss are included, the number rises to 28 million. Although there have been considerable advances in understanding the etiology of hearing loss, with genetic causes now thought to account for up to 50% of congenital losses, in many individual cases, the cause of hearing loss remains unknown. This lack of knowledge of the basic pathophysiology of hearing difficulties hampers prevention and treatment efforts. Growing interest in life course theory has led to suggestions that it could prove useful to apply a life course lens to the study of hearing loss, and of hearing health, throughout the life span. In this paper we consider the implications of the Life Course Health Development model for understanding the mechanisms, pathways, and determinants of hearing ability. We consider the implications of early hearing loss for health development over the life course and the factors through the life course that contribute to hearing ability in adult life. We consider the concept not just of hearing loss but of “hearing health” and how to achieve it, the research priorities that are suggested by this review, and the implications for policy and practice.

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High Risk of Sensorineural Hearing Loss in Men Born Small for Gestational Age with and without Obesity or Height Catch-Up Growth: A Prospective Longitudinal Register Study on Birth Size in 245,000 Swedish Conscripts

Abstract: The thrifty phenotype hypothesis also seems to be valid for SNHL, meaning that SNHL in adulthood may originate from events during fetal life. SNHL might be a new clinical feature of the metabolic syndrome.

Cited by 52 publications

References 24 publications

BMI over the lifecourse and hearing ability at age 45 years: a population based study

BMI over the lifecourse and hearing ability at age 45 years: a population based study

Peripheral Insensate Neuropathy- Is Height a Risk Factor?

A Life Course Approach to Hearing Health

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