High-Risk Human Papillomavirus Detection and Related Risk Factors Among Pregnant and Nonpregnant Women in Mexico

Abstract

Our results are consistent with other studies reporting increased high-risk HPV detection rates among pregnant women. HPV-positive status in pregnant and nonpregnant women appears to be influenced by age. The decrease in HPV positivity by number of pregnancies in both currently pregnant and nonpregnant women is consistent with a possible effect of immune protection as a result of earlier HPV infections. Despite lack of information about a woman's history of sexual behavior, these data support the hypothesis that an alteration of immunologic responses during pregnancy may be associated with an increased risk of HPV acquisition or reactivation.

Effect of Second Pregnancy on Maternal Carriage and Outcome of High-Risk Human Papillomavirus (HPV)

“…Previous longitudinal studies addressing this subject are scarce [9,22] and the crosssectional studies do no allow evaluation of fluctuation of HR-HPV during and between the pregnancies. Some previous studies have suggested that increasing parity might decrease the risk of HPV infection [3,4] , and this has for example been speculated to be due to increased immunity to infection [4,22,23] .…”

“…The effect of pregnancy on human papillomavirus (HPV) carriage has been a controversial issue [1][2][3][4] . It has been suggested that pregnancy could increase the risk of HPV infection due to pregnancy-related hormonal changes and/or immunosuppression [1] , but the majority of the reports do not substantiate this conclusion [5][6][7][8][9][10][11] .…”

Diagnostic et prise en charge des lésions précancéreuses du col utérin pendant la grossesse

“…En effet, les très rares publications sur ce domaine semblent montrer une prévalence égale [51][52][53] ou supérieure [54][55][56][57] de positivité pour les HPV à haut risque pendant la grossesse dont la signification n'est pas claire (tolérance immune liée à la grossesse. .…”

Cáncer Cérvico-Uterino Asociado Al Embarazo: Reporte De Un Caso

“…La infección por este virus es un hallazgo probable en la mujer embarazada, estudios recientes han reportado la detección de VPH de alto riesgo por medio de DNA en el 37,2% de las mujeres embarazadas y en el 14,2% de mujeres no embarazadas; los tipos oncogénicos de VPH 16 y 18 son los más comunes en el embarazo (14). Por ello, es importante la tipificación viral en cualquier paciente embarazada o no, que presente una lesión premaligna o cancerosa.…”

“…Desde hace 20 años se ha publicado que el embarazo no parece influir en el pronóstico del cán-cer de cuello uterino; no existe evidencia de que la sobrevida sea diferente cuando se compara con la de pacientes sin embarazo de la misma edad, estadio y tipo histológico (11,14). Sin embargo, el efecto del embarazo en la historia natural de la lesión intraepitelial cervical es controversial, algunos autores reportan que el embarazo no modifica la progresión de las lesiones moderadas a severas, otros describen una alta incidencia de regresión en el postparto (10).…”