High risk and low prevalence diseases: Orbital cellulitis

Pelletier, Jessica; Koyfman, Alex; Long, Brit

doi:10.1016/j.ajem.2023.02.024

Cited by 9 publications

(10 citation statements)

References 92 publications

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“…Preseptal and orbital cellulitis occur especially in childhood, often after untreated or delayed treatment of paranasal sinus and oral cavity infections. It may lead to decreased eye movements, proptosis, and severe neurologic complications [18]. In the present study, more than 25% of the participants were diagnosed with conjunctivitis and preseptal and orbital cellulitis.…”

Section: Discussionmentioning

confidence: 49%

Ophthalmologic emergencies in pediatric patients aged 0–2 years

Cumaoglu,

Dolanbay,

Vural

et al. 2024

Med-Science

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Ophthalmologic emergencies (OE) in the pediatric age group are classified as traumatic or nontraumatic, potentially causing partial or total visual loss. These emergencies, which are significant contributors to acquired visual impairment or loss, hold a prominent position in emergency department visits globally. This retrospective study aimed to analyze the demographic, etiological, and clinical characteristics of patients aged 0–2 years who were brought to the Emergency Department (ED) with ophthalmologic emergencies and requested ophthalmologic consultation. Age (month), sex, complaint etiology, affected eye (right or left), diagnosis, examination findings, treatment, and clinical progression were analyzed. Of the patients, 26 who met the inclusion criteria were included in this study. The median age was 20 (14.75–24) months; 5 (19.2%) children were aged less than 1 year and 21 (80.8%) were aged more than 1 year. Three of the patients (11.5%) were refugees. When the cases were grouped as infective and noninfective eye emergencies, the diagnosis of conjunctivitis was statistically significant between refugee and nonrefugee children (p=0.032). Traumatic injuries were more common in children aged 13–24 months, which was statistically significant (p=0.029). Only a small proportion of children brought to emergency departments with ocular complaints actually have a genuine emergency necessitating consultation. Early pediatric patients, in particular, should undergo a more meticulous systemic examination. It is crucial to explore the presence of severe emergencies that could lead to vision loss, one of our most vital senses, in every patient.

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Section: Discussionmentioning

confidence: 49%

Ophthalmologic emergencies in pediatric patients aged 0–2 years

Cumaoglu,

Dolanbay,

Vural

et al. 2024

Med-Science

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“…We report a pediatric case of orbital LCH who presented with left eyelid swelling and erythema, which led to a misdiagnosis of orbital cellulitis by the attending ophthalmologist. Although the incidence of LCH and orbital cellulitis are predominantly found in childhood [ 4 ], it is important to note that normal extraocular muscle motility and blood test results do not correspond to findings of orbital cellulitis. In addition, orbital LCH has a typical CT finding of a soft-tissue mass in the superolateral orbit centered in the frontal bones with osteolytic lesions [ 5 , 6 ], which was evident in our case.…”

Section: Discussionmentioning

confidence: 99%

Orbital Langerhans Cell Histiocytosis: A Case Report

Yokoyama,

Someda,

Kakizaki

et al. 2023

Cureus

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An eight-year-old boy presented with a one-month history of left eyelid swelling. The patient was diagnosed with periorbital cellulitis at another clinic and was treated with oral antibiotics. However, the swelling did not subside. On initial consultation, the patient had left upper eyelid swelling with erythema. His extraocular muscle motility was normal, and the results of blood tests were unremarkable. A computed tomographic scan demonstrated a mass in the superior orbit with destructive changes in the left frontal bone. Histopathological examinations revealed a dense infiltrate of histiocytic cells. Immunohistochemical staining of the tumors for CD1a and Langerin was positive. A pathological diagnosis of Langerhans cell histiocytosis was made. Since orbital Langerhans cell histiocytosis has a high risk for central nervous system involvement, chemotherapy was the treatment of choice for any residual lesion to prevent sequelae to the central nervous system. At the six-month follow-up, the lesion did not recur, and the patient did not experience any central nervous system sequela.

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“…Umgekehrt lassen sich die Weichteilstrukturen mit dem MRT besser beurteilen, was Vorteile bei der Stadienzuordnung der Erkrankung bietet. Daher und auf Grund der fehlenden Strahlenbelastung wird von einigen Autoren das MRT dem CT als überlegen angesehen [6,25]. Da eine MRT Untersuchung nicht immer sofort verfügbar ist und sich die knöchernen Strukturen der Schädelbasis in der CT besser abgrenzen lassen, was für eine evtl.…”

Section: Diagnostikunclassified

“…Alternativ zum CT bzw. DVT wird von einigen Autoren die Durchführung eines MRT empfohlen, wegen einer besseren Darstellung der Weichteilstrukturen, womit eine bessere Aussage zur Ausbreitung der Entzündung in der Orbita möglich sei 15 25 . Da eine MRT Untersuchung jedoch nicht immer sofort verfügbar ist und bei kleinen Kindern überdies eine Narkose für die Dauer der Datenaufnahme notwendig ist, gilt das CT bzw.…”

Section: Orbitale Komplikationenunclassified

Interdisziplinäre Therapie der Erkrankungen der Orbita

Eckstein,

Welkoborsky

2024

Laryngorhinootologie

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ZusammenfassungDie Diagnostik und Therapie von Erkrankungen der Orbita ist eine interdisziplinäre Aufgabe, an der u.a. die Fachdisziplinen HNO-Heilkunde, Augenheilkunde, Radiologie, Strahlentherapie, MKG-Chirurgie, Endokrinologie und Pädiatrie beteiligt sind. Der vorliegende Übersichtsartikel stellt eine Zusammenstellung der häufigsten Erkrankungen dar, mit denen die Fachdisziplinen HNO-Heilkunde und Augenheilkunde interdisziplinär befasst sind. Es werden die akuten entzündlichen Erkrankungen incl. orbitaler Komplikationen, die autoimmunologischen Erkrankungen der Orbita incl. der endokrinen Orbitopathie, und die tumorösen Erkrankungen besprochen. Neben der Diagnostik und der Beschreibung der Klinik wird besonderes Augenmerk auf die interdisziplinäre Therapie gelegt. Abgerundet wird der Übersichtsartikel mit der Beschreibung der wichtigsten chirurgischen Zugangswege zur Orbita, ihre Indikationen und mögliche Komplikationen. Die Autoren haben versucht, trotz der knappen Darstellung die relevanten Fakten zu beschreiben.

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High risk and low prevalence diseases: Orbital cellulitis

Cited by 9 publications

References 92 publications

Ophthalmologic emergencies in pediatric patients aged 0–2 years

Ophthalmologic emergencies in pediatric patients aged 0–2 years

Orbital Langerhans Cell Histiocytosis: A Case Report

Interdisziplinäre Therapie der Erkrankungen der Orbita

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