High-Resolution Ultrasonography of Primary Peripheral Soft Tissue Lymphoma

Chiou, Hong‐Jen; Chou, Yi‐Hong; Chiou, See-Ying; Chen, Wei-Ming; Chen, Winby; Wang, Hsin‐Kai; Chang, Cheng-Yen

doi:10.7863/jum.2005.24.1.77

Cited by 46 publications

(37 citation statements)

References 25 publications

(12 reference statements)

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“…At US of cases of lymphoma in the salivary gland, one may observe a solitary, hypoechoic, homogeneous or inhomogeneous lesion, which is oval or lobulated or has irregular margins and sometimes contains echogenic septa or stripes (34,110,111). However, these features are not pathognomonic, and lymphoma may not be reliably differentiated from other neoplastic or nonneoplastic salivary gland tumors with US.…”

Section: Lymphomamentioning

confidence: 95%

“…However, these features are not pathognomonic, and lymphoma may not be reliably differentiated from other neoplastic or nonneoplastic salivary gland tumors with US. A pattern of multiple hypoechoic lesions with increased blood flow may also be seen (34,111). Such a pattern requires differentiation from inflammation, Sjö gren syndrome, granulomatous disease (eg, sarcoidosis), and hematogenous metastases (23,25,32,33,42,43).…”

Section: Lymphomamentioning

confidence: 99%

“…Differential diagnosis of Sjö gren syndrome with disseminated lymphoma in salivary glands may be challenging. Non-Hodgkin lymphoma manifesting as small multiple nodular disseminations with hypervascularization in the salivary gland has been reported (34,65). In addition, bilateral inflammation (acalculous), granulomatous disease (eg, sarcoidosis), hematogenous metastases, and benign lymphoepithelial lesions in HIV-positive patients should be taken into consideration in cases of multiple hypoechoic areas scattered in salivary gland parenchyma (23,25,33,35,42,43).…”

Section: Sjö Gren Syndromementioning

confidence: 99%

See 2 more Smart Citations

US of the Major Salivary Glands: Anatomy and Spatial Relationships, Pathologic Conditions, and Pitfalls

Białek¹,

Jakubowski²,

Zajkowski³

et al. 2006

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Section: Lymphomamentioning

confidence: 95%

Section: Lymphomamentioning

confidence: 99%

Section: Sjö Gren Syndromementioning

confidence: 99%

See 1 more Smart Citation

US of the Major Salivary Glands: Anatomy and Spatial Relationships, Pathologic Conditions, and Pitfalls

Białek¹,

Jakubowski²,

Zajkowski³

et al. 2006

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254

242

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“…In the neck, the soft tissue commonly has a layered or sliced outline, where an irregular or oval nodule linked to a primary lesion can be unequivocally detected. 18,19 The contrast of hypoechoic lesions to relatively hyperechoic thyroid lobes helps determinate thyroid involvement. All of the invasions of the soft tissues (n = 6) and gland (n = 3) were correctly diagnosed in this study.…”

mentioning

confidence: 99%

Sonographic Assessment of Hypopharyngeal Carcinoma

Xia

Zhu

Cheng

et al. 2011

Journal of Ultrasound in Medicine

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Preliminary Studyt is usually difficult to detect hypopharyngeal carcinoma at an early stage because of inconspicuous pharyngeal symptoms. The patient often presents with advanced disease that has a poor prognosis. 1 Endoscopic and imaging examinations are considered indispensable approaches in diagnosis of hypopharyngeal carcinoma. Endoscopy can be used to directly observe a tumor arising from mucosa, on which biopsy can be performed. Additionally, its ability to show the laryngeal structure and movement is helpful for tumor staging. 2 However, it is difficult to determine the depth and extrahypopharyngeal invasion of advanced carcinoma, and it is frequently impossible to visualize the inferior part of a bulky lesion that obstructs passage of the endoscope. Xia, MD, Qiang Zhu, MD, Yun Cheng, MD, Han Xue Zhao, MD, Zhen Zhen Jin, MD Received July 20, 2010, Chun Xia ORIGINAL RESEARCHObjectives-This study investigated the ability of sonography for diagnosis of hypopharyngeal carcinoma.Methods-Between November 2008 and January 2010, 34 consecutive patients with hypopharyngeal carcinoma (34 tumors) were examined by sonography. The visualization capability of sonography was evaluated by grading criteria of "excellent," "good," "moderate," and "poor" in comparison with computed tomography (CT). Localization of the primary tumor foci and intrahypopharyngeal and extrahypopharyngeal invasion were initially assessed by sonography and confirmed with surgical and pathologic findings. Laryngeal movement was observed on real-time sonography and compared with endoscopic findings.Results-On sonography, 29 of the 34 lesions (85.3%) were graded excellent, similar to the shapes and dimensions of the tumors on CT. Localization was correctly undertaken in 26 of the 28 foci resected (92.9%), with excellent agreement between sonography and surgical and pathologic findings (κ = 0.823; P < .001). In evaluating intrahypopharyngeal and extrahypopharyngeal invasion with sonography, the sensitivity and specificity were 90.9% and 82.4%, respectively, for intrahypopharyngeal intersubsite spreading, 50.0% and 96.2% for diagnosis of thyroid cartilage destruction, both 100% for evaluation of cervical esophagus, neck soft tissue, and thyroid gland involvement, and 76.9% and 100% for assessment of hemilarynx fixation.Conclusions-Sonography has a similar role in visualization of hypopharyngeal carcinoma as CT and is satisfactory in localization of the primary focus and assessment of tumor extension inside and outside the hypopharynx.

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“…Admittedly, a conventional angiogram was obtained as part of surgical planning. Ultrasonography can be used to aid in core needle biopsy in the diagnosis of lymphoma [9]. In addition, with masses or disease of the submandibular gland, ultrasonography represents an easy, first-line investigation for identification of extraglandular spread and determination of cystic degeneration of the gland [10].…”

Section: Diagnostic Evaluationmentioning

confidence: 99%

Contemporary management of tumors of the salivary glands

Scianna¹,

Petruzzelli

2007

Curr Oncol Rep

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Management of tumors of the salivary glands requires a detailed understanding of the anatomy and pathologic processes affecting these glands. Salivary glands give rise to benign and malignant neoplasms and are affected by a variety of systemic diseases. CT remains the most common primary imaging study; magnetic resonance imaging and ultrasound have also been explored. Fine-needle aspiration as part of the diagnostic evaluation remains controversial due to varying sensitivities and specificities. Surgical extirpation is the primary modality for management of tumors of the salivary glands. Parotid surgery carries a potentially high morbidity with possible unsightly scarring and facial nerve damage. Nontraditional surgical approaches and instrumentation, as well as facial nerve monitoring, can decrease the morbidity of a parotidectomy. In specific instances, malignant salivary gland tumors warrant cervical lymphadenectomy. Adjuvant therapy is primarily accomplished with radiation. Chemotherapy continues to play a palliative role in salivary gland malignancies; however, newer trials are investigating the therapeutic role of chemotherapy.

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High-Resolution Ultrasonography of Primary Peripheral Soft Tissue Lymphoma

Abstract: In patients with a soft-tissue mass, routine plain radiography and high-resolution ultrasonography including color Doppler ultrasonography are recommended before further evaluation with ultrasonographically guided biopsy.

Cited by 46 publications

References 25 publications

US of the Major Salivary Glands: Anatomy and Spatial Relationships, Pathologic Conditions, and Pitfalls

US of the Major Salivary Glands: Anatomy and Spatial Relationships, Pathologic Conditions, and Pitfalls

Sonographic Assessment of Hypopharyngeal Carcinoma

Contemporary management of tumors of the salivary glands

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