A simple, efficient, and general method has been developed for the synthesis of various 4-substituted 2-amino-6,6-diphenyl-8-aryl-6,8-dihydroimidazo[1,2-a] [1,3,5] triazine-7(4-H)ones 3a-3v. This involved condensation of 1-(5-oxo-4,4-diphenyl-1-aryl-4,5-dihydro-1H-imidazol-2-yl)guanidines 2a and 2b, themselves obtained from the reaction of aryl biguanides 1a/b with benzil, with the requisite carbonyl compounds. Both steps were performed using microwave heating in sealed vessels.