High-resolution MRI vessel wall enhancement in moyamoya disease: risk factors and clinical outcomes

Hao, Fangbin; Han, Cong; Lu, Mingming; Wang, Yue; Gao, Gan; Wang, Qiannan; Liu, Shitong; Liu, Simeng; Wang, Minjie; Ren, Bin; Zou, Zhengxing; Yu, Dan; Sun, Caihong; Zhang, Qian; Guo, Qingbao; Liu, Wanyang; Sun, Zhenghui; Cai, Jianming; Duan, Lian

doi:10.1007/s00330-023-10535-0

Cited by 2 publications

(1 citation statement)

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“…In a study by Li et al, hyperthyroidism was found in 0.9% of normal children, which is lower than the 10.5% seen in children with MMD ( p = 0.003) ( Li et al, 2011 ). In MMD, the ring finger protein 213 p.R4810K variant is strongly associated with vessel wall enhancement (VWE) and poor prognosis ( Hao et al, 2024 ). A total of 16 million Asians living outside of Asia carry this RNF213 variant ( Liu et al, 2012 ).…”

Section: Pathologic Features Of MMDmentioning

confidence: 99%

High-resolution magnetic resonance vessel wall imaging provides new insights into Moyamoya disease

Yang,

Huang,

et al. 2024

Front. Neurosci.

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Moyamoya disease (MMD) is a rare condition that affects the blood vessels of the central nervous system. This cerebrovascular disease is characterized by progressive narrowing and blockage of the internal carotid, middle cerebral, and anterior cerebral arteries, which results in the formation of a compensatory fragile vascular network. Currently, digital subtraction angiography (DSA) is considered the gold standard in diagnosing MMD. However, this diagnostic technique is invasive and may not be suitable for all patients. Hence, non-invasive imaging methods such as computed tomography angiography (CTA) and magnetic resonance angiography (MRA) are often used. However, these methods may have less reliable diagnostic results. Therefore, High-Resolution Magnetic Resonance Vessel Wall Imaging (HR-VWI) has emerged as the most accurate method for observing and analyzing arterial wall structure. It enhances the resolution of arterial walls and enables quantitative and qualitative analysis of plaque, facilitating the identification of atherosclerotic lesions, vascular entrapment, myofibrillar dysplasia, moyamoya vasculopathy, and other related conditions. Consequently, HR-VWI provides a new and more reliable evaluation criterion for diagnosing vascular lesions in patients with Moyamoya disease.

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Section: Pathologic Features Of MMDmentioning

confidence: 99%