High-resolution gadolinium-enhanced 3D MRA of the infrapopliteal arteries

Hood, Maureen N.; Ho, Vincent B.; Foo, Thomas K.F.; Marcos, Hani B.; Hess, Sandra L.; Choyke, Peter L.

doi:10.1016/s0730-725x(02)00531-3

Cited by 26 publications

(14 citation statements)

References 18 publications

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“…18 carotid arteries were evaluated in the 9 patients in group A (Gadobutrol-enhanced MRA) and 42 carotid arteries were evaluated in the 21 patients in group B (Gadoteridol-enhanced MRA) ( Table 1). The average contrast agent volume administered was 7.3 ± 1.2 ml [6][7][8][9][10] in group A and 14 ± 1.9 ml [11][12][13][14][15][16][17][18] (Fig. 1).…”

Section: Resultsmentioning

confidence: 99%

“…Moreover, it is the sole agent approved for high-dose administration (0.3 mmol/kg) due in part to its high stability and thus lower potential for toxicity from long-term heavy metal deposition [11,12]. Despite the inherent safety of Gadoteridol, only a few studies have evaluated the performance of this contrast medium in MRA [13][14][15][16].…”

Section: Introductionmentioning

confidence: 99%

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Accuracy of gadoteridol enhanced MR-angiography in the evaluation of carotid artery stenosis

Zaccagna

Sacconi

Saba

et al. 2015

Neurovascular Imaging

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Background: To compare image quality and diagnostic performance of Gadoteridol-enhanced MR angiography (MRA) with Gadobutrol-enhanced MRA in the evaluation of carotid artery stenosis. Methods: MRA was performed in 30 patients with carotid stenosis diagnosed at DUS. Patients were randomly assigned to group A (Gadobutrol-enhanced MRA) or group B (Gadoteridol-enhanced MRA). All examinations were performed with a 3T MR system. Image quality was assessed qualitatively by a 3-grade scale and quantitatively with SNR measurements. Diagnostic performance in the assessment of stenosis, plaque length and morphology was evaluated in the two MRA groups by accuracy calculation and RoC curves analysis using CTA as reference standard. Statistically significant differences in SNR and quality scale were evaluated by the Independent-Samples T Test and Mann-Whitney test, while the Z-statistics was used to compare diagnostic accuracy in the two groups. Results: Image quality was graded adequate to excellent for both GBCAs, without significant differences (p = 0.165). SNR values were not significantly different in group B (Gadoteridol-enhanced MRA) as compared to group A (Gadobutrol-enhanced MRA) (89.32 ± 70.4 vs 81.09 ± 28.38; p = 0.635). Diagnostic accuracy was 94 % for the evaluation of stenosis degree and 94 % for the identification of ulcerated plaques in group A, while it was 93 % for the evaluation of stenosis degree and 76 % for the identification of ulcerated plaques in group B, without statistically significant differences (p = 0.936). Conclusion: No significant difference in terms of image quality and diagnostic accuracy was observed between Gadoteridol-enhanced MRA and Gadobutrol-enhanced MRA in patients undergoing evaluation of carotid stenosis.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Accuracy of gadoteridol enhanced MR-angiography in the evaluation of carotid artery stenosis

Zaccagna

Sacconi

Saba

et al. 2015

Neurovascular Imaging

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“…SENSE), use of slight compression to reduce the venous return flow and using 2-D techniques for the calf [23]. In patients with increased AV shunts (peripheral arteriosclerosis disease, diabetes mellitus, venous insufficiency) the hybrid technique could alternatively be used; in this, first the calf and foot arteries are scanned with a 3-D GRE CE-MRA sequence and afterwards the pelvic and thigh region are scanned with the same sequence in a table-movement procedure over two FOVs [24]. Vessels of the calf and foot are often visualised better with this technique than with i.a.…”

Section: Clinical Indicationsmentioning

confidence: 99%

Importance of CE-MRA in various body regions - Comparison with i.a. DSA

Hentsch¹

2004

European Radiology Supplements

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Non-CE MRA techniques are black-or white-blood techniques. In the black-blood technique the signal-loss phenomenon in a spin-echo (SE) or fast-spin-echo (FSE) sequence is used, while in TOF or PC techniques the flowing blood generates a bright signal, engendered by the in-flow effect in TOF and by phase shift in PC [8]. The black-blood technique is used for detailed high-resolution imaging of the vessel wall (e.g., for coronary arteries) or of arteriosclerotic plaques. TOF angiography is used mainly for imaging of intracerebral vessels or, rarely, of carotids, or of hand or foot arteries. PC angiography has supplanted most other methods in most indications and is used almost exclusively in brain AV malformation, dural fistula diagnosis and pre-interventional planning (flow measurement). Quantitative flow measurement to detect haemodynamically relevant stenosis and the detection of flow direction (e.g. subclavian-steel syndrome) proceeds by phase-contrast imaging [9]. It may be expected to play an important part in diagnosis and in patient management accompanying therapy.The problems of non-CE MRA techniques are well known. These include, for example, longer acquisition time, saturation effects in TOF and phase wrapping in PC.In CE-MRA, the arterial first pass of an intravenously applied contrast agent is adapted to a 3-D gradient echo (GRE) sequence with short TR and TE values. The extracellular contrast agent shortens the T1 longitudinal relaxation time in proportion to the concentration of contrast agent in the blood [10,11]. Owing to short TR and TE values of a 3-D gradient echo sequence, the signal from the surrounding tissue is suppressed.To optimise the image quality, it is necessary to adapt the timing of contrast bolus injection, the flow rate and the amount of contrast agent to the measurement sequence. The contrast bolus peak is optimised by homogenous filling of the central k-space (responsible for contrast) of the sequence [12,13]. The contrast bolus peak is

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“…The bolus chasing method is not a very new concept in the angiograms. It has been studied in digital subtraction angiography (DSA) [7] and magnetic resonance angiography (MRA) [8][9][10][11][12]. However, both DSA and MRA modalities have a larger field of view (FOV) in the z direction.…”

Section: Introductionmentioning

confidence: 99%

Adaptive bolus chasing computed tomography angiography by a local linear time and space parameter varying model: modeling, control, identification, and experimental results

Cai

Wang

Bai

2010

Front. Electr. Electron. Eng. China

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A high contrast to noise ratio (CNR) is always desirable for contrast-enhanced computed tomography angiography (CTA). To ensure a high CNR of the vascular images in CTA and potentially reduce the radiation exposure and contrast usage, an adaptive bolus chasing method is proposed and evaluated compared to the existing constant-speed method. The proposed method is based on a local time and space parameter varying model of the contrast bolus. Optimal scan time for the next segment of the vasculature is estimated and predicted in real time and guides the computed tomography (CT) scanner table movement that guarantees that each segment of the vasculature is scanned with the maximum possible enhancement. Simulations and experimental results show that the proposed bolus chasing method outperforms the conventional constant-speed method substantially.

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High-resolution gadolinium-enhanced 3D MRA of the infrapopliteal arteries

Cited by 26 publications

References 18 publications

Accuracy of gadoteridol enhanced MR-angiography in the evaluation of carotid artery stenosis

Accuracy of gadoteridol enhanced MR-angiography in the evaluation of carotid artery stenosis

Importance of CE-MRA in various body regions - Comparison with i.a. DSA

Adaptive bolus chasing computed tomography angiography by a local linear time and space parameter varying model: modeling, control, identification, and experimental results

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