High-Resolution Flat-Panel Volume-CT of Temporal Bone-Part 1

Bartling, Sönke; Shukla, Vershalee; Becker, H.; Brady, Thomas J.; Hayman, Anne; Gupta, Rajiv

doi:10.1097/01.rct.0000165796.14732.43

Cited by 18 publications

(7 citation statements)

References 2 publications

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“…The resulting boost in spatial resolution is quite apparent from system characterization experiments. Such high spatial resolution, combined with the large volume coverage, allows for superior bone imaging, especially in complex areas such as the temporal bone [8][9][10][11][12][13][14].…”

Section: Resultsmentioning

confidence: 99%

Ultra-high resolution flat-panel volume CT: fundamental principles, design architecture, and system characterization

et al. 2006

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Digital flat-panel-based volume CT (VCT) represents a unique design capable of ultra-high spatial resolution, direct volumetric imaging, and dynamic CT scanning. This innovation, when fully developed, has the promise of opening a unique window on human anatomy and physiology. For example, the volumetric coverage offered by this technology enables us to observe the perfusion of an entire organ, such as the brain, liver, or kidney, tomographically (e.g., after a transplant or ischemic event). By virtue of its higher resolution, one can directly visualize the trabecular structure of bone. This paper describes the basic design architecture of VCT. Three key technical challenges, viz., scatter correction, dynamic range extension, and temporal resolution improvement, must be addressed for successful implementation of a VCT scanner. How these issues are solved in a VCT prototype and the modifications necessary to enable ultra-high resolution volumetric scanning are described. The fundamental principles of scatter correction and dose reduction are illustrated with the help of an actual prototype. The image quality metrics of this prototype are characterized and compared with a multi-detector CT (MDCT).

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Section: Resultsmentioning

confidence: 99%

Ultra-high resolution flat-panel volume CT: fundamental principles, design architecture, and system characterization

et al. 2006

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“…Flat-panel volume CT is an imaging modality that combines the advances in CT with digital flat-panel-detector technology and is capable of high-resolution (150 ϫ 150 ϫ 150-m) in vivo imaging (24)(25)(26). There are other high-resolution CT scanners, such as the highresolution peripheral quantitative CT scanner, with a spatial resolution of approximately 80 m (16,27), and the micro-CT scanner, used for in vitro or small-animal imaging, with a spatial resolution of approximately 10 -20 m (17,27).…”

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confidence: 99%

Distal Radius in Adolescent Girls with Anorexia Nervosa: Trabecular Structure Analysis with High-Resolution Flat-Panel Volume CT

Bredella

Misra²,

Miller³

et al. 2008

Radiology

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Purpose:To examine trabecular microarchitecture with high-resolution flat-panel volume computed tomography (CT) and bone mineral density (BMD) with dual-energy x-ray absorptiometry (DXA) in adolescent girls with anorexia nervosa (AN) and to compare these results with those in normal-weight control subjects. Materials and Methods:The study was approved by the institutional review board and complied with HIPAA guidelines. Informed consent was obtained. Twenty adolescent girls, 10 with mild AN (mean age, 15.9 years; range, 13-18 years) and 10 ageand sex-matched normal-weight control subjects (mean age, 15.9 years; range, 12-18 years) underwent flat-panel volume CT of distal radius to determine apparent trabecular bone volume fraction (BV/TV), apparent trabecular number (TbN), apparent trabecular thickness (TbTh), and apparent trabecular separation (TbSp). All subjects underwent DXA of spine, hip, and whole body to determine BMD and body composition. The means and standard deviations (SDs) of structure parameters were calculated for AN and control groups. Groups were compared (Student t test). Linear regression analysis was performed. Results:AN subjects compared with control subjects, respectively, showed significantly lower mean values for BV/TV (0.37% Ϯ 0.05 [SD] vs 0.46% Ϯ 0.03, P ϭ .0002) and TbTh (0.31 mm Ϯ 0.03 vs 0.39 mm Ϯ 0.03, P Ͻ .0001) and higher mean values for TbSp (0.54 mm Ϯ 0.13 vs 0.44 mm Ϯ 0.04, P ϭ .02). TbN was lower in AN subjects than in control subjects, but the difference was not significant (1.17 mm Ϫ3 Ϯ 0.15 vs 1.22 mm Ϫ3 Ϯ 0.07, P ϭ .43). There was no significant difference in BMD between AN and control subjects. BMD parameters showed positive correlation with BV/TV and TbTh in the control group (r ϭ 0.55-0.84, P ϭ .05-.01) but not in AN patients. Conclusion:Flat-panel volume CT is effective in evaluation of trabecular structure in adolescent girls with AN and demonstrates that bone structure is abnormal in these patients compared with that in normal-weight control subjects despite normal BMD. RSNA, 2008 Note: This copy is for your personal, non-commercial use only. To order presentation-ready copies for distribution to your colleagues or clients, use the Radiology Reprints form at the end of this article. Low bone mineral density (BMD) is a serious complication of anorexia nervosa (AN) in adults and adolescents (1,2). Decreased bone mass occurs in multiple skeletal sites and is associated with a sevenfold increased fracture risk that may persist despite recovery (3,4). The onset of AN during the adolescent years is of particular concern because this is a crucial time for bone mass accrual toward achievement of peak bone mass. Deficits in the normal rate of bone mass accrual during this period can result in low peak bone mass and an increased risk of fractures in adult life (2,5). Dual-energy x-ray absorptiometry (DXA) is commonly used for the assessment of BMD; however, it is highly influenced by body size (6), which provides a diagnostic challenge in children with AN, because prolon...

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“…Presumably, diagnostics in assessing active and passive middle ear prostheses will be simplified by a further development of 3D postprocessing software and improved by introducing new CT technologies like flat-panel volume CT. 34 This will lead radiologists to make themselves familiar with the problems arising from active and passive middle ear prosthetics.…”

Section: Discussionmentioning

confidence: 99%

Three-Dimensional Imaging of Active and Passive Middle Ear Prostheses Using Multislice Computed Tomography

Burmeister

Bisdas²,

Baltzer³

et al. 2008

Journal of Computer Assisted Tomography

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High-Resolution Flat-Panel Volume-CT of Temporal Bone-Part 1

Cited by 18 publications

References 2 publications

Ultra-high resolution flat-panel volume CT: fundamental principles, design architecture, and system characterization

Ultra-high resolution flat-panel volume CT: fundamental principles, design architecture, and system characterization

Distal Radius in Adolescent Girls with Anorexia Nervosa: Trabecular Structure Analysis with High-Resolution Flat-Panel Volume CT

Three-Dimensional Imaging of Active and Passive Middle Ear Prostheses Using Multislice Computed Tomography

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