High-resolution computed tomography of asbestos-related diseases

Aberle, Denise R.

doi:10.1016/0037-198x(91)90006-a

Cited by 27 publications

(13 citation statements)

References 51 publications

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“…Interpretation of parenchymal abnormalities on HRCT characteristic of asbestosis were based on published descriptions [4, 9, 11, 12]. These abnormalities include: (1) subpleural curvilinear lines; (2) parenchymal bands (non-tapering linear opacities, 2–5 cm in length extending usually to areas of pleural thickening); (3) thickened interlobular septal lines and intralobular core structures, and (4) honeycombing (small cyst-like spaces up to 1 cm in diameter with discrete walls).…”

Section: Methodsmentioning

confidence: 99%

“…There are three principal benign pleural manifestations of asbestos exposure including circumscribed pleural plaques, benign exudative effusions and diffuse pleural fibrosis [4]. Among these, pleural plaques are the most common radiographic manifestations of asbestos exposure [5].…”

Section: Introductionmentioning

confidence: 99%

“…Although conventional radiological examinations of the thorax such as chest X-rays can show, at least in part, asbestos-related changes in the thorax, high-resolution computed tomography (HRCT) has been found to demonstrate these lesions more accurately [4, 6, 7, 8, 9]. Nevertheless, most CT protocols tend to sample only middle and lower parts of the thorax, which do not effectively visualize the whole lung, therefore, a CT protocol that scans all parts of the thorax may be more appropriate, since asbestosis-related changes may involve not only the lower lobes, but also the upper lobes [6].…”

Section: Introductionmentioning

confidence: 99%

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High-Resolution Computed Tomography in Cases with Environmental Exposure to Asbestos in Turkey

Topçu

Bayram²,

Şimşek³

et al. 2000

Respiration

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Background and Objectives: Although all parts of the lung can be affected as a consequence of asbestos exposure, most CT protocols tend to scan only the middle and lower parts of the thorax. The aim of this study was to investigate parenchymal and pleural lesions of persons exposed to environmental asbestos, using a high-resolution computed tomography (HRCT) protocol scanning the whole thorax. Methods: We analyzed the chest radiographs and HRCT scans of 26 patients who presented bilaterally with multiple pleural plaques related to environmental asbestos exposure. Results: Twenty-four cases (92%) had an abnormal HRCT suggestive of asbestosis. Apart from common HRCT changes related to asbestosis, we detected apical pleural thickening (APT) in 9 cases as well as a coarse honeycomb pattern adjacent to APT in 7 of these cases. Cavitary lesions due to pulmonary tuberculosis were observed on HRCT scans from 4 patients in total. Neither apical pulmonary fibrosis nor cavitary lesions were visible on chest radiographs. Conclusions: We suggest that the HRCT protocol for examining asbestos-exposed individuals with pleural plaques on chest X-rays should include the whole thorax, since the asbestos-related pathologies may involve all parts of the lung.

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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High-Resolution Computed Tomography in Cases with Environmental Exposure to Asbestos in Turkey

Topçu

Bayram²,

Şimşek³

et al. 2000

Respiration

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“…HRCT is generally regarded as more sensitive than chest radiographs and conventional CT, and HRCT findings correlate with restriction, as described above. Pleural disease can be more readily distinguished from normal chest wall structures, and underlying parenchyma can be imaged in the presence of extensive overlying pleura (47,48 of dusts. Improved imaging techniques such as HRCT may improve the sensitivity of readings, particularly at the low end of the spectrum, although the reading of plain films by two experienced B readers did comparably well in one controlled study (50).…”

Section: Lung Burden Studiesmentioning

confidence: 99%

Health Effects of Asbestos and Nonasbestos Fibers

Osinubi¹,

Gochfeld²,

Kipen³

2000

Environmental Health Perspectives

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“…In combined asbestos and cigarette smoke exposure, HRCT may play a role in distinguishing emphysematous lung destruction from peripheral interstitial changes of asbestosis (24). However, expense, time, and the lack of established standards for technique and image interpretation make the use of HRCT inappropriate for initial screening (21,26 (27). An asbestos body (Fig.…”

Section: Asbestosismentioning

confidence: 99%

A retired shipyard worker with rapidly progressive pulmonary interstitial fibrosis.

Moy¹,

Hu²,

Christiani³

1999

Environ Health Perspect

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We present a case of progressive interstitial fibrosis in a retired shipyard worker who was exposed to asbestos during the postwar era of the late 1940s and 1950s, when asbestos exposures in the workplace were not regulated. Forty years later, at 63 years of age, the patient presented with restrictive lung disease. The patient was diagnosed with asbestos-related pleural disease and parenchymal asbestosis. He remained stable for the next 7 years, but then he began to manifest rapid clinical progression, which raised the possibility of an unusual variant of asbestosis, a concomitant interstitial process, or an unrelated disease. Lung biopsy was not undertaken because of the patient's low pulmonary reserve and limited treatment options. An empiric trial of oral steroids was initiated, but his pulmonary status continued to deteriorate and he died of pulmonary failure at 72 years of age. Many diseases result in pulmonary interstitial fibrosis. Ideally, open lung biopsy should be performed, but this procedure inevitably causes complications in many patients with end-stage restrictive lung disease. Furthermore, while the presence of asbestos bodies in tissue sections is a sensitive and specific marker of asbestos exposure, neither this finding nor any other charge is a marker indicative of asbestosis or the severity of asbestosis. With the enactment of the Asbestos Standard in the United States, asbestos exposures have been decreasing in this country. However, industries that produce asbestos products and wastes continue to expand in developing countries. Prevention of asbestos-related lung disease should be a global endeavor, and asbestos exposures should be regulated in both developed and developing countries. Images Figure 1 Figure 2 Figure 3 Figure 4

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High-resolution computed tomography of asbestos-related diseases

Cited by 27 publications

References 51 publications

High-Resolution Computed Tomography in Cases with Environmental Exposure to Asbestos in Turkey

High-Resolution Computed Tomography in Cases with Environmental Exposure to Asbestos in Turkey

Health Effects of Asbestos and Nonasbestos Fibers

A retired shipyard worker with rapidly progressive pulmonary interstitial fibrosis.

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