High-resolution computed tomography and rheumatoid arthritis: semi-quantitative evaluation of lung damage and its correlation with clinical and functional abnormalities

Yılmazer, Barış; Gümüştaş, Sevtap; Coşan, Fulya; İnan, Nagihan; Ensaroğlu, Fatih; Erbağ, Gökhan; Yıldız, Füsun; Çefle, Ayşe

doi:10.1007/s11547-015-0590-5

Cited by 17 publications

(13 citation statements)

References 35 publications

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“…Our study failed to find any association between smoking and pulmonary abnormalities. In agreement with our study, Sakre et al (7) found no association to smoking Bilgici et al (13) stated that smoking was not associated with physiological or HRCT abnormalities suggestive of RA ILD Zhang et al (11) . concluded that smoking is a significant risk factor for the development of ILD in RA patients .…”

Section: Discussionsupporting

confidence: 93%

“…Results of Sakre et al (20) . Bilgici et al (7) agreed with us and found no association with medications (20) (7). This result suggests that changes detected by HRCT may occur as a result of RA associated factors rather than treatment given.…”

Section: Discussionsupporting

confidence: 71%

“…Hence, it is important to perform ILD screening in elderly RA patients. Sakre et al (7) found no association with age .…”

Section: Discussionmentioning

confidence: 93%

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Prevalence of Pulmonary Manifestations in a Cohort of the Egyptian Patients with Rheumatoid Arthritis

Baky

Mohamed

Hosney

et al. 2017

Egyptian Journal of Hospital Medicine

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Background: rheumatoid arthritis can affect the lung in many ways including lung parenchymal affection (Interstitial lung disease), pleural inflammation, upper and lower airways affection and pulmonary vasculature. Aim of the work: this study aimed to estimate the prevalence of pulmonary manifestations in Egyptian RA patients. Patients and methods: this study included seventy patients with RA. All patients were subjected to detailed medical history taking, general examination including chest examination, local musculoskeletal examination, laboratory investigations including CBC, ESR, CRP titre, ALT, AST, BUN and creatinine, rheumatoid factor titer (RF), Anti-CCP antibodies titer, radiological investigations including chest X ray, HRCT and PFT. Results: pulmonary manifestations were prevalent in 50% of patients. Spirometric abnormalities were detected in 45.7%, while HRCT abnormalities were detected in 42.85%. HRCT severity score was correlated with age, tender joint count (TJC), swollen joint count (SJC) and ESR. There was a statistically significant negative correlation between HRCT and FVC, FEV1. There was no correlation regarding other parameters. Conclusion: pulmonary affection was prevalent in RA and can be detected by radiological and pulmonary functions. There was correlation with age, ESR and pulmonary

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Section: Discussionsupporting

confidence: 93%

Section: Discussionsupporting

confidence: 71%

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Prevalence of Pulmonary Manifestations in a Cohort of the Egyptian Patients with Rheumatoid Arthritis

Baky

Mohamed

Hosney

et al. 2017

Egyptian Journal of Hospital Medicine

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“…[3][4][5][6] Bu genifl aral›¤›n nedeni altta yatan BDH ve ‹AH tan›s› için kullan›lan tan›sal yöntemin farkl›l›¤›d›r. Tan› için kullan›lan yönteme göre s›kl›k de¤iflmektedir; özellikle radyolojik yöntemler kullan›ld›¤›n-da s›kl›k daha da yüksek de¤erlere ulaflmaktad›r.…”

Section: Prevalans Ve Risk Faktörleriunclassified

“…Oysa ‹AH tan›s› için solunum fonksiyon testleri (SFT) ve karbonmonoksit difüzyon kapasitesi (DLCO) kullan›ld›¤›nda bu s›kl›k %40'lara, yüksek çözünürlüklü bilgisayarl› tomografi (HRCT) ile %60-80'lere ç›kmakta, akci¤er biyopsisi yap›lan serilerde ise bu oran %80'lere varmaktad›r. [1,2,4] Benzer flekilde sistemik sklerozda (SSc) akci¤er biyopsisi yap›lan serilerde s›kl›k %60-90 iken sadece klinik bulgular baz ald›¤›nda s›kl›k %26, akci¤er grafisi baz al›nd›¤›nda ise %22 olarak bildirilmifltir. [1,2,5] Altta yatan BDH göre s›kl›¤a bak›ld›¤›nda genel olarak en s›k SSc'de, en az s›k-l›kta ise sistemik lupus eritematozusta (SLE) ‹AH saptand›¤› görülmektedir (Tablo 1).…”

Section: Prevalans Ve Risk Faktörleriunclassified

Connective tissue diseases related interstitial lung disease: diagnostic and treatment approaches

Yazıcı¹,

Çefle²

2016

RAED Derg

Self Cite

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Impact of COVID-19 pneumonia on interstitial lung disease: semi-quantitative evaluation with computed tomography

et al. 2023

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Objectives To evaluate the CT scores and fibrotic pattern changes in interstitial lung disease (ILD) patients, with and without previous COVID-19 pneumonia. Methods Patients with ILD (idiopathic pulmonary fibrosis (IPF) and connective tissue disease-associated ILD (CTD-ILD)) were retrospectively enrolled in the study which consisted of patients who had COVID-19 pneumonia while the control group had not. All patients had two CT scans, initial and follow-up, which were evaluated semi-quantitatively for severity, extent, and total CT scores, fibrosis patterns, and traction bronchiectasis. Results A total of 102 patients (pneumonia group n = 48; control group n = 54) were enrolled in the study. For both groups, baseline characteristics were similar and CT scores were increased. While there was a 4.5 ± 4.6 point change in the total CT score of the COVID-19 group, there was a 1.2 ± 2.7 point change in the control group ( p < 0.001). In the IPF subgroup, the change in total CT score was 7.0 points (95% CI: 4.1 to 9.9) in the COVID-19 group and 2.1 points (95% CI: 0.8 to 3.4) in the control group. Seven patients (14.6%) in the COVID-19 group progressed to a higher fibrosis pattern, but none in the control group. Conclusions Semi-quantitative chest CT scores in ILD patients demonstrated a significant increase after having COVID-19 pneumonia compared to ILD patients who had not had COVID-19 pneumonia. The increase in CT scores was more prominent in the IPF subgroup. There was also a worsening in the fibrosis pattern in the COVID-19 group. Key Points • The impact of COVID-19 pneumonia on existing interstitial lung diseases and fibrosis is unclear . • COVID-19 pneumonia may worsen existing interstitial lung involvement with direct lung damage and indirect inflammatory effect . • COVID-19 pneumonia may affect existing lung fibrosis by triggering inflammatory pathways .

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High-resolution computed tomography and rheumatoid arthritis: semi-quantitative evaluation of lung damage and its correlation with clinical and functional abnormalities

Abstract: It is considered that this semi-quantitative method may have added value in early diagnosis, appropriate treatment decisions and follow-up when taken into account together with risk factors associated with pulmonary damage in RA.

Cited by 17 publications

References 35 publications

Prevalence of Pulmonary Manifestations in a Cohort of the Egyptian Patients with Rheumatoid Arthritis

Prevalence of Pulmonary Manifestations in a Cohort of the Egyptian Patients with Rheumatoid Arthritis

Connective tissue diseases related interstitial lung disease: diagnostic and treatment approaches

Impact of COVID-19 pneumonia on interstitial lung disease: semi-quantitative evaluation with computed tomography

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