High-resolution computed microtomography for the characterization of a diffusion tensor imaging phantom

Abstract

This paper addresses the issue of the quantitative characterization of the structure of the calibration model (phantom) for b-matrix spatial distribution diffusion tensor imaging (BSD-DTI) scanners. The aim of this study was to verify manufacturing assumptions of the structure of materials, since phantoms are used for BSD-DTI calibration directly after manufacturing. Visualization of the phantoms' structure was achieved through optical microscopy and high-resolution computed microtomography (lCT). Using lCT images, a numerical model of the materials structure was developed for further quantitative analysis. 3D image characterization was performed to determine crucial structural parameters of the phantom: porosity, uniformity and distribution of equivalent diameter of capillary bundles. Additionally calculations of hypothetical flow streamlines were also performed based on the numerical model that was developed. The results obtained in this study can be used in the calibration of DTI-BST measurements. However, it was found that the structure of the phantom exhibits flaws and discrepancies from the assumed geometry which might affect BSD-DTI calibration.

The Impact of Microwave Drying on the Structure of Exemplary Soils—Insights Using X-ray Microtomography

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Detailed parametrization of the pore space in tight clastic rocks from Poland based on laboratory measurement results

“…The paper presents the combination of various laboratory measurement results: computed X-ray tomography (nanoscale), nuclear magnetic resonance spectroscopy and also pulse-and pressure-decay permeability method. Computed X-ray tomography (CT) is a well-known method in medicine and material engineering (Al-Raoush and Papadopoulos 2010; Kaczmarek et al 2017). Physical bases of the method are connected with the X-ray absorption coefficient (Stock 2008).…”