High-resolution Chest CT Features and Clinical Characteristics of Patients Infected with COVID-19 in Jiangsu, China

Abstract

Background: A pneumonia associated with the coronavirus disease 2019 (COVID-19) recently emerged in China. It was recognized as a global health hazard. Methods: 234 inpatients with COVID-19 were included. Detailed clinical data, chest HRCT basic performances and certain signs were recorded Ground-glass opacity (GGO), consolidation, fibrosis and air trapping were quantified. Both clinical types and CT stages were evaluated. Results: Most patients (approximately 90%) were classified as common type and with epidemiologic history. Fever and cough were main symptoms. Chest CT showed abnormal attenuation in bilateral multiple lung lobes, distributed in the lower and/or periphery of the lungs (94.98%), with multiple shapes. GGO and vascular enhancement sign were most frequent seen, followed by interlobular septal thickening and air bronchus sign as well as consolidation, fibrosis and air trapping. There were significant differences in most of CT signs between different stage groups. The SpO2 and OI were decreased in stage IV, and the CT score of consolidation, fibrosis and air trapping was significantly lower in stage I (P < 0.05). A weak relevance was between the fibrosis score and the value of PaO2 and SpO2 (P < 0.05). Conclusions: Clinical performances of patients with COVID-19, mostly with epidemiologic history and typical symptoms, were critical valuable in the diagnosis of the COVID-19. While chest HRCT provided the distribution, shape, attenuation and extent of lung lesions, as well as some typical CT signs of COVID-19 pneumonia.

The importance of repeat testing in detecting coronavirus disease 2019 (COVID‐19) in a coronary artery bypass grafting patient

“…Obtaining CT imaging should also be an integral component of screening for COVID‐19 in cardiac surgical patients. Typical CT findings include consolidation, vascular enhancement, air bronchus sign, and bilateral peripheral ground‐glass opacities with interlobular septal thickening consistent with a “crazy paving pattern.” 7 In our case, these features prompted continued isolation of our patient as presumed‐positive. While these findings can reinforce clinical suspicion, they may also be found in other viral syndromes making them fairly nonspecific.…”

<strong>Early Oxygen Inhalation to Prevent SARS-CoV-2-Induced Acute Respiratory Distress Syndrome</strong>

“…15 However a recent study demonstrated that patients in the stage IV group (classified by CT images with bilateral diffuse lesions in more than half of the lung field) showed only slightly-declined SpO2 (94.70±0.20%). 16 While the stage II patients with only a small proportion of lung injury and HPV showed relatively high SpO2 (97.2±0.91%). 16 Thus the diagnostic standard of SpO2 either ≤90% or ≤93% may be too low to take the oxygen therapy in time.…”

“…16 While the stage II patients with only a small proportion of lung injury and HPV showed relatively high SpO2 (97.2±0.91%). 16 Thus the diagnostic standard of SpO2 either ≤90% or ≤93% may be too low to take the oxygen therapy in time.…”

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“…Besides, GLCM considers the statistical and spatial relationship of the pixels in the image. It is created by calculating how often pairs of pixel with speci c values and in a speci ed spatial relationship occur in an image [5]. Then 13 statistical texture features are extracted based on the grey level co-occurrence matrix.…”