High Rates of Readmission in Necrotizing Pancreatitis: Natural History or Opportunity for Improvement?

Maatman, Thomas K.; Mahajan, Sarakshi; Roch, Alexandra M.; Lewellen, Kyle A.; Heimberger, Mark A.; Colgate, Cameron L.; Ceppa, Eugene P.; House, Michael G.; Nakeeb, Attila; Schmidt, C. Max; Zyromski, Nicholas J.

doi:10.1007/s11605-018-04097-6

Cited by 29 publications

(19 citation statements)

References 15 publications

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“…Readmission rates in studies that included all patients treated for AP ranged from 7 to 34% and varied depending on etiology, disease severity, and medical comorbidities [ [8] , [9] , [10] , [11] , [12] , [13] , [14] , [15] , [16] , [17] , [18] , [19] , [20] , [21] , [22] , [23] , [24] , [25] , [26] , [27] , [28] , [29] , [30] ], Fig. 1 .…”

Section: Resultsmentioning

confidence: 99%

Readmission in acute pancreatitis: Etiology, risk factors, and opportunities for improvement

Bogan¹,

McGuire²,

Maatman³

2022

Surgery Open Science

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Section: Resultsmentioning

confidence: 99%

Readmission in acute pancreatitis: Etiology, risk factors, and opportunities for improvement

Bogan¹,

McGuire²,

Maatman³

2022

Surgery Open Science

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“…11e13 Necrotizing pancreatitis is an acute process that associates with a prolonged disease course, the need for intensive care, frequent readmission, high rates of infection, and the need for invasive interventions. 12,14,15 Studies cataloging and critically evaluating the complications in survivors of NP are lacking. Available series are often small in sample size, have limited follow-up, or are restricted to discrete complications such as pancreatic insufficiency, chronic pancreatitis, quality of life, and hernia.…”

Section: Introductionmentioning

confidence: 99%

The continuum of complications in survivors of necrotizing pancreatitis

Maatman

Roch

Ceppa

et al. 2020

Surgery

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Background: Necrotizing pancreatitis survivors develop complications beyond infected necrosis that often require invasive intervention. Remarkably few data have cataloged these late complications after acute necrotizing pancreatitis resolution. We sought to identify the types and incidence of complications after necrotizing pancreatitis. Design: An observational study was performed evaluating 647 patients with necrotizing pancreatitis captured in a single-institution database between 2005 and 2017 at a tertiary care hospital. Retrospective review and analysis of newly diagnosed conditions attributable to necrotizing pancreatitis was performed. Exclusion criteria included the following: death before disease resolution (n ¼ 57, 9%) and patients lost to follow-up (n ¼ 12, 2%). Results: A total of 578 patients were followed for a median of 46 months (range, 8 months to 15 y) after necrotizing pancreatitis. In 489 (85%) patients 1 or more complications developed and included symptomatic disconnected pancreatic duct syndrome (285 of 578, 49%), splanchnic vein thrombosis (257 of 572, 45%), new endocrine insufficiency (195 of 549, 35%), new exocrine insufficiency (108 of 571, 19%), symptomatic chronic pancreatitis (93 of 571, 16%), incisional hernia (89 of 420, 21%), biliary stricture (90 of 576, 16%), chronic pain (44 of 575, 8%), gastrointestinal fistula (44 of 578, 8%), pancreatic duct stricture (30 of 578, 5%), and duodenal stricture (28 of 578, 5%). During the follow-up period, a total of 340 (59%) patients required an invasive intervention after necrotizing pancreatitis resolution. Invasive pancreatobiliary intervention was required in 230 (40%) patients. Conclusion: Late complications are common in necrotizing pancreatitis survivors. A broad variety of problems manifest themselves after resolution of the acute disease process and often require invasive intervention. Necrotizing pancreatitis patients should be followed lifelong by experienced clinicians.

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“…Patients with NP usually have a protracted and variable disease course because pancreatic and peripancreatic necrosis may liquefy or remain solid, become infected or remain sterile, or persist or disappear over time ( 21 , 36 ). In our results, biliary AP showed an increasing percentage of NP on CT from Phase I to Phase IV, while hypertriglyceridemic AP showed a decreasing percentage from Phase I to IV.…”

Section: Discussionmentioning

confidence: 99%

Computed tomography characteristics of acute pancreatitis based on different etiologies at different onset times: a retrospective cross-sectional study

Du¹,

Zhang²,

Zhang³

et al. 2022

Quant Imaging Med Surg

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Background: The clinical characteristics and imaging findings of acute pancreatitis (AP) are different across the various etiologies, the results are conflicting, and their time from symptom onset to imaging varies. The imaging findings of different etiologies at different onset times are unclear. This study aimed to investigate the computed tomography (CT) characteristics of AP based on different etiologies at different onset times. Methods: Patients who underwent plain and contrast-enhanced computed tomography (CECT) for the first attack of AP in 3 hospitals (Affiliated

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High Rates of Readmission in Necrotizing Pancreatitis: Natural History or Opportunity for Improvement?

Cited by 29 publications

References 15 publications

Readmission in acute pancreatitis: Etiology, risk factors, and opportunities for improvement

Readmission in acute pancreatitis: Etiology, risk factors, and opportunities for improvement

The continuum of complications in survivors of necrotizing pancreatitis

Computed tomography characteristics of acute pancreatitis based on different etiologies at different onset times: a retrospective cross-sectional study

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