High prevalence of vitamin D deficiency among healthy Saudi Arabian men: relationship to bone mineral density, parathyroid hormone, bone turnover markers, and lifestyle factors

Ardawi, M. S. M.; Sibiany, Abdulrahman; Bakhsh, Talal M.; Qari, Mohammed H.; Maimani, A. A.

doi:10.1007/s00198-011-1606-1

Cited by 178 publications

(192 citation statements)

References 52 publications

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“…20 Similarly, the same authors in another study reported a prevalence of vitamin D deficiency among Saudi women of 80%, 21 which is lower compared with our figure (98%). Our higher prevalence might be attributed to the fact that our sample is clinic-based, compared with their community-based sample.…”

Section: Discussioncontrasting

confidence: 45%

“…Similarly, Ardawi et al 20 found that sedentary life and lack of physical activity are associated with lower levels of vitamin D. Nonetheless, it is not clear whether the physical activity is a factor that leads to increases in vitamin D level, or conversely it is vitamin D that improves physical activity. In fact, studies of dialysis patients 25,26 and older frail people 27,28 demonstrated an amelioration of the abilities of physical exertion, and subsequently improved the quality of life of these persons.…”

Section: Discussionmentioning

confidence: 99%

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Comparison of vitamin D deficiency in Saudi married couples

2012

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BACKGROUND/OBJECTIVE: Vitamin D deficiency is highly prevalent in Saudi Arabia. The study objective was to compare vitamin D deficiency in Saudi married couples. SUBJECTS/METHODS: This cross-sectional study was carried out in the Royal Guard primary health care center in Riyadh, Saudi Arabia on a consecutive sample of 50 Saudi married couples attending the center without complaints related to vitamin D deficiency. Data were collected through an interview questionnaire addressing the risk factors and dietary habits. Quantitative determination of total 25-hydroxy vitamin D in blood was done by Electro-Chemical Luminescence assay. Fieldwork was carried out from December 2010 to January 2011. RESULTS: Men had higher sun exposure (P ¼ 0.001), more use of light clothes at home (P ¼ 0.002) and more intake of milk (P ¼ 0.023) and soft drinks (P ¼ 0.001). Vitamin D was higher in men with mean difference about 9 nmol/l (Po0.001). The prevalence of vitamin D deficiency (o25 nmol/l) was 70% in women, compared with 40% in men (P ¼ 0.001). Multivariate analysis identified male gender, physical activity and the intake of milk as statistically significant positive independent predictors of vitamin D level, adjusted for factors as age, sun exposure, clothing, skin color, BMI, soft drinks and animal protein intake. CONCLUSION: Vitamin D deficiency is very high among Saudi married couples, especially wives. Female gender is an independent predictor of lower vitamin D level, in addition to sedentary lifestyle and low milk consumption. There is a need to revise the levels set for the diagnosis of vitamin D deficiency or insufficiency in the study region.

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Section: Discussioncontrasting

confidence: 45%

Section: Discussionmentioning

confidence: 99%

Comparison of vitamin D deficiency in Saudi married couples

2012

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“…Substantially low VD levels, much lower than those found in European, were reported among women (Tomaschitz et al, 2010), men and women (Vaidya and Williams, 2012;Zittermann, 2006) and healthy adolescents (Chowdhury et al, 2009). This is attributed, in part to ageing, obesity, sedentary lifestyle, illiteracy, poor dietary vitamin D supplementation, and despite its abundance, poor exposure to sunlight (Ardawi et al, 2012). However, little is known about the relationship between VD deficiency and insufficiency and QoL in the Gulf Arab population.…”

Section: Introductionmentioning

confidence: 94%

“…Vitamin D may also protect against osteoporosis, high blood pressure, cancer, and other diseases. 1,25(OH)2D is known to have many protective features, such as the inhibition of cellular proliferation and inducing terminal differentiation, inhibiting angiogenesis, stimulating insulin production, inhibiting renin production, and stimulating macrophage cathelicidin production (Zittermann, 2006;Dawodu et al, 1998;Elshafie et al ., 2012;Ardawi et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

Vitamin-D deficiency and insufficiency and quality of life in Jeddah, KSA: Is there any evidence of association

Alsowai¹,

Bakr²

2018

J. Public Health Epidemiol.

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Vitamin D (VD) deficiency and insufficiency have been linked to poor quality of life (QoL); general weakness, fatigue, and nonspecific pain. Despite abundance of sun light, there is a wide spread VD deficiency in the Arabian Gulf countries. However, the impact of VD deficiency on the quality of life has not been well documented in the Arabian Gulf countries, including the Kingdom of Saudi Arabia (KSA). This study aims to analyze the effect of crude vitamin D levels on quality of life in none pregnant Arab women in the Kingdom of Saudi Arabia (KSA). The study was a prospective cross sectional study, using a sample of 152 subjects of patients aged 13 years and above attending the outpatients' clinic at King Faisal Hospital, Kingdom of Saudi Arabia (KSA). The study collected anthropometric and demographic variables, in addition to a small plasma sample from all subjects to measure VD levels, calcium (Ca), phosphorus (P), parathyroid hormone (PTH) and lipid profile by standard methods. Subjects were categorized according to VD levels as normal (>30 ng/ml), insufficiency (21 to 29 ng/ml), or deficient (≤ 20 ng/ml). The RAND Short Form -36 (SF-36), which consists of 36 questionnaire items was used to measure (QoL) across eight domains for both physically and emotional wellbeing: physical functioning; role limitations due to physical health; role limitations due to emotional problems; energy/fatigue; emotional well-being; social functioning; pain and general health. Logistic regression analysis was used to investigate the associations between VD levels and QoL. The mean scores in the total sample were 65.5 (SD ±14.6) for the physical component summary (PCS) score and 58.2 (SD ±15.2) for the mental component summary score (MCS). Vitamin D deficiency was overwhelmingly high among subjects across age and sex. The PCS and MCS QoL scores were also lower than the average. However, the study found no association between VD levels and QoL, presumably due to sample size and con-founders. Further studies are needed to identify the impact of VD levels on perceived QoL.

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“…Aunque anteriormente se consideró que la deficiencia de esta vitamina era un problema común sólo de los países que carecían de un clima soleado la mayor parte del año, los resultados de investigación confirman cada vez más que la deficiencia de VD es un problema de salud pública (10), incluso en países que disfrutan de una temperatura cálida la mayor parte del año (11). Por consiguiente, la necesidad de cuantificar esta vitamina en forma precisa para lograr establecer una asociación no espuria entre un fenotipo determinado y los niveles sanguíneos de VD, se ha convertido en un reto, en especial con fines de investigación traslacional.…”

Section: Introductionunclassified

Cuantificación De Vitamina D: De La Investigación a La Práctica Clínica

Díaz

Mahecha

González

et al. 2017

biosa

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RESUMENLas formas biológicamente activas de la vitamina D se han convertido en elementos de gran relevancia en la práctica clínica y la investigación, por lo tanto, su análisis se ha incrementado en años recientes. La vitamina D tiene un papel esencial en la regulación del metabolismo del calcio y fósforo; adicionalmente, esta vitamina es considerada un posible factor preventivo para diversas enfermedades crónicas como la diabetes mellitus tipo 2, algunos tipos de cáncer, cardiovasculares, autoinmunes, enfermedad pulmonar obstructiva crónica y la pre-eclampsia. Debido al posible papel en estas enfermedades y a los pocos estudios comparativos que se han realizado entre éstas y los niveles de vitamina D, los investigadores y clínicos están interesados en usar técnicas confiables y específicas que permitan determinar las concentraciones de vitamina D en el plasma. Sin embargo, no se ha establecido cuál es el mejor biomarcador que refleja la suficiencia de vitamina D y su función, ni tampoco cuál es la mejor técnica para su adecuada cuantificación. QUANTIFICATION OF VITAMIN D: FROM RESEARCH TO CLINICAL PRACTICE ABSTRACTThe analysis of the biologically active forms of vitamin D has increased in the last decades, becoming a relevant tool in the clinical practice and investigation. Vitamin D plays an essential role in regulating the metabolism of calcium and phosphorous. In addition, this vitamin is considered a potential preventive factor in a wide range of chronical diseases such as cardiovascular and autoimmune diseases, different kinds of cancer, type 2 diabetes,

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High prevalence of vitamin D deficiency among healthy Saudi Arabian men: relationship to bone mineral density, parathyroid hormone, bone turnover markers, and lifestyle factors

Cited by 178 publications

References 52 publications

Comparison of vitamin D deficiency in Saudi married couples

Comparison of vitamin D deficiency in Saudi married couples

Vitamin-D deficiency and insufficiency and quality of life in Jeddah, KSA: Is there any evidence of association

Cuantificación De Vitamina D: De La Investigación a La Práctica Clínica

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