High Prevalence of Undetected Vitamin D Deficiency in an Urban Minority Primary Care Practice

Kahn, Linda S.; Satchidanand, Nikhil; Kopparapu, Anil; Goh, Winston D.; Yale, Sandra; Fox, Chester H.

doi:10.1016/s0027-9684(15)30337-0

Cited by 7 publications

(4 citation statements)

References 19 publications

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“…In addition, intravenous drug use increases the risk for a host of acute and chronic infectious and cardiopulmonary conditions. As a result, this patient population suffers a disproportionate burden of 25(OH)D deficiency, compared to other urban dwelling adults [ 26 , 27 ]. In 2014, Lambert et al evaluated the relationship between intravenous drug use, 25(OH)D deficiency, and HIV infection, analysing 950 individuals (29% of them were HIV-infected).…”

Section: Risk Factors For Vitamin D Deficiency In Hiv-infected Submentioning

confidence: 99%

Vitamin D Deficiency in HIV Infection: Not Only a Bone Disorder

Mansueto

Seidita

Vitale

et al. 2015

BioMed Research International

100

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Hypovitaminosis D is a worldwide disorder, with a high prevalence in the general population of both Western and developing countries. In HIV patients, several studies have linked vitamin D status with bone disease, neurocognitive impairment, depression, cardiovascular disease, high blood pressure, metabolic syndrome, type 2 diabetes mellitus, infections, autoimmune diseases like type 1 diabetes mellitus, and cancer. In this review, we focus on the most recent epidemiological and experimental data dealing with the relationship between vitamin D deficiency and HIV infection. We analysed the extent of the problem, pathogenic mechanisms, clinical implications, and potential benefits of vitamin D supplementation in HIV-infected subjects.

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Section: Risk Factors For Vitamin D Deficiency In Hiv-infected Submentioning

confidence: 99%

Vitamin D Deficiency in HIV Infection: Not Only a Bone Disorder

Mansueto

Seidita

Vitale

et al. 2015

BioMed Research International

100

View full text Add to dashboard Cite

show abstract

“…The majority of the total sample size consisted of women (73%) and African Americans (88%). Although the study did not indicate the number of African American female subjects, 75% of females and 91% of African American subjects were reported to have low serum 25(OH) D concentrations, providing supporting evidence of the prevalence of vitamin D deficiency/ insufficiency among females and African Americans [23].…”

Section: Vitamin D Insufficiency In African Americans and African Amementioning

confidence: 67%

“…In studies specifically focusing on African American females, the majority of subjects were deemed vitamin D insufficient or deficient regardless of age or location [22,23]. One study was conducted in Waco, Texas at a latitude of 31°N, assessing a small sample size (n = 38) of African American elderly women (≥ 70 years old) to determine serum 25(OH) D insufficiency prevalence.…”

Section: Vitamin D Insufficiency In African Americans and African Amementioning

confidence: 99%

African American Females: A Potential Link Between Vitamin D Insufficiency and Type-2 Diabetes

Soriano

Zhang

2014

JNHFE

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“…As a result, this patient population suffers a disproportionate burden of vitamin D deficiency compared to other urban dwelling adults [12], [13]. Moreover, IDUs have increased risks for drug overdose, drug-related morbidity and mental health conditions which render the study of chronic conditions associated with vitamin D deficiency difficult [14].…”

Section: Introductionmentioning

confidence: 99%

Risk Factors for Vitamin D Deficiency among HIV-Infected and Uninfected Injection Drug Users

et al. 2014

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IntroductionVitamin D deficiency is highly prevalent and is associated with bone disease, cardiovascular disease, metabolic syndrome and malignancy. Injection drug users (IDUs), with or without HIV infection, are at risk for these conditions; however, limited data on vitamin D deficiency exist in this population. We determined the prevalence and correlates of vitamin D deficiency among urban IDUs in the AIDS Linked to the IntraVenous Experience (ALIVE) Study cohort.MethodsFor this cross-sectional sub-study, vitamin D deficiency was defined as a serum 25(OH)-vitamin D level <20 ng/mL. Multivariable logistic regression was used to identify factors independently associated with vitamin D deficiency.ResultsOf 950 individuals analyzed, 29% were HIV-infected. The median age was 49 years; 65% were male, and 91% were black. The median vitamin D level was 13.5 ng/mL (IQR, 9.0–20.3); 74% were deficient (68% in HIV-infected vs. 76% in HIV-uninfected, p = 0.01). Non-black race, fall/winter season, multivitamin intake, higher serum albumin, HCV seropositivity and HIV-infection were associated with significantly lower odds of vitamin D deficiency.ConclusionsVitamin D deficiency is prevalent among IDUs. Notably, HIV-infected IDUs were less likely to be vitamin D deficient. Higher vitamin D levels were associated with multivitamin intake and with higher albumin levels, suggesting that nutritional status contributes substantially to deficiency. The association between HCV serostatus and vitamin D level remains unclear. Further investigation is needed to define the clinical implications of the heavy burden of vitamin D deficiency in this high-risk, aging population with significant co-morbidities.

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High Prevalence of Undetected Vitamin D Deficiency in an Urban Minority Primary Care Practice

Cited by 7 publications

References 19 publications

Vitamin D Deficiency in HIV Infection: Not Only a Bone Disorder

Vitamin D Deficiency in HIV Infection: Not Only a Bone Disorder

African American Females: A Potential Link Between Vitamin D Insufficiency and Type-2 Diabetes

Risk Factors for Vitamin D Deficiency among HIV-Infected and Uninfected Injection Drug Users

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