High Prevalence of Mycoplasma pneumoniae and Chlamydia pneumoniae in Children with Acute Respiratory Infections from Lima, Peru

Valle-Mendoza, Juana del; Orellana-Peralta, Fiorella; Marcelo-Rodríguez, Alvaro; Verne, Eduardo; Esquivel-Vizcarra, Mónica; Silva-Caso, Wilmer; Aguilar-Luis, Miguel Ángel; Weilg, Pablo; Oré, Verónica Casabona; Ugarte, Claudia; Valle, Luís J. del

doi:10.1371/journal.pone.0170787

Cited by 33 publications

(46 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…[21][22][23] Studies conducted in Latin America report frequencies ranging from 0.74% to 43.8%. [24][25][26] Most of the reports are from a previously healthy pediatric population.…”

Section: Discussionmentioning

confidence: 99%

Viral and bacterial coinfection among hospitalized children with respiratory tract infections

Liu

Zhao

Xiao³

et al. 2020

American Journal of Infection Control

View full text Add to dashboard Cite

Background: The epidemiology of Mycoplasma pneumoniae (MP) and local dominant etiologies of pathogens that cause respiratory tract infections (RTIs) among central China children (≤14 years old) hospitalized are poorly understood. Methods: A total of 10,429 specimens were analyzed, and IgM antibodies against 9 respiratory pathogens including MP were detected using indirect immunofluorescence assay from serum. Results: It showed that 59.3% of the enrolled children were positive for at least 1 pathogen; highest detection rates included those between 3 and <6 years of age (70.4%), female (63.2%), and who were hospitalized in 2014 (80.9%). The most predominant pathogen was MP (45.6%), followed by Parainfluenza viruses (PIVs) (22.6%) and influenza B viruses (IFVB) (14.7%). Coinfection was observed in 2,907 specimens (27.9%); the coinfection combination containing MP and PIVs had the highest detection rate of 15%, followed by MP and IFVB as well as IFVB and PIVs. Conclusions: MP was the most commonly detected bacteria among hospitalized children, which should be included in the differential diagnosis for hospitalized children with RTI. These findings will contribute to the effective prevention and therapeutic approaches of pathogens among local children suffering from RTI.

show abstract

“…[21][22][23] Studies conducted in Latin America report frequencies ranging from 0.74% to 43.8%. [24][25][26] Most of the reports are from a previously healthy pediatric population.…”

Section: Discussionmentioning

confidence: 99%

Viral and bacterial coinfection among hospitalized children with respiratory tract infections

Liu

Zhao

Xiao³

et al. 2020

American Journal of Infection Control

View full text Add to dashboard Cite

show abstract

“…Für Chlamydien konnte die Saisonalität nicht so eindeutig gezeigt werden. Bei eine Untersuchung von akuten respiratorischen Infektionen in Peru ergab sich zwar für Mykoplasmen der bekannte E ekt einer signi kanten Fallzahl im Sommer, nicht jedoch für Chlamydien [16]. Auch Chen et al kamen bei der Untersuchung chinesischer Kindern zu dem Schluss, dass Mykoplasmen-Erkrankungen im Sommer häu g sind, Chlamydien dagegen im Winter deutlich häu ger vorkommen [17].…”

Section: Mykoplasmen Und Chlamydienunclassified

Sommergrippe: Mehr als ein Mythos!

Bogner

2019

MMW - Fortschritte der Medizin

View full text Add to dashboard Cite

Sommergrippe: Mehr als ein Mythos! Durchsucht man die deutschsprachige medizinische Literatur nach dem Begriff "Sommer grippe", scheitert man kläglich. Jeder glaubt zu wissen, was damit gemeint ist, doch keiner schreibt darüber. Ist das überhaupt ein seriöses Thema? © Thomas_EyeDesign / Getty Images / iStock (Symbolbild mit Fotomodell) Plötzlich hohes Fieber: Hat sie eine "Sommergrippe"? 39 MMW Fortschritte der Medizin 2019 . 12 / 161 FORTBILDUNG . SCHWERPUNK T 42 MMW Fortschritte der Medizin 2019 . 12 / 161 FORTBILDUNG . SCHWERPUNK T FORTBILDUNG MMW Fortschritte der Medizin 2019 . 12 / 161

show abstract

“…Classically, S. pneumoniae and H. influenzae type b are the most commonly isolated bacteria in both throat and nasopharyngeal specimens from patients with ARIs [9,10]. However, in resource-limited countries, atypical bacteria such as Mycoplasma pneumoniae, Chlamydia pneumoniae, and Bordetella pertussis can play an important role in ARIs and can be detected in more than 40% of patients [2,[11][12][13][14].…”

Section: Introductionmentioning

confidence: 99%

Identfication of viral and bacterial etiologic agents of the pertussis-like syndrome in children under 5 years old hospitalized

et al. 2019

Self Cite

View full text Add to dashboard Cite

BackgroundAcute respiratory infections (ARIs) represent an important cause of morbidity and mortality in children, remaining a major public health concern, especially affecting children under 5 years old from low-income countries. Unfortunately, information regarding their epidemiology is still limited in Peru.MethodsA secondary data analysis was performed from a previous cross-sectional study conducted in children with a probable diagnosis of Pertussis from January 2010 to July 2012. All samples were analyzed via Polymerase Chain Reaction (PCR) for the following etiologies: Influenza-A, Influenza-B, RSV-A, RSV-B, Adenovirus, Parainfluenza 1 virus, Parainfluenza 2 virus, Parainfluenza 3 virus, Mycoplasma pneumoniae and Chlamydia pneumoniae.ResultsA total of 288 patients were included. The most common pathogen isolated was Adenovirus (49%), followed by Bordetella pertussis (41%) from our previous investigation, the most prevelant microorganisms were Mycoplasma pneumonia (26%) and Influenza-B (19.8%). Coinfections were reported in 58% of samples and the most common association was found between B. pertussis and Adenovirus (12.2%).ConclusionsThere was a high prevalence of Adenovirus, Mycoplasma pneumoniae and other etiologies in patients with a probable diagnosis of pertussis. Despite the presence of persistent cough lasting at least two weeks and other clinical characteristics highly suspicious of pertussis, secondary etiologies should be considered in children under 5 years-old in order to give a proper treatment.Electronic supplementary materialThe online version of this article (10.1186/s12879-019-3671-6) contains supplementary material, which is available to authorized users.

show abstract

High Prevalence of Mycoplasma pneumoniae and Chlamydia pneumoniae in Children with Acute Respiratory Infections from Lima, Peru

Cited by 33 publications

References 26 publications

Viral and bacterial coinfection among hospitalized children with respiratory tract infections

Viral and bacterial coinfection among hospitalized children with respiratory tract infections

Sommergrippe: Mehr als ein Mythos!

Identfication of viral and bacterial etiologic agents of the pertussis-like syndrome in children under 5 years old hospitalized

Contact Info

Product

Resources

About