High prevalence of diabetes in an urban population in south India.

Ramachandran, Ambady; Jali, M.V.; Mohan, Viswanathan; Snehalatha, Chamukuttan; Viswanathan, M

doi:10.1136/bmj.297.6648.587

Cited by 186 publications

(106 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Few studies findings were reported by various researchers in India regarding female preponderance in Indian diabetics similar to present study as reported by Ramaiya et al, Ramachandran et al and Lipscombe LL et al [13][14][15] The response rate among men was relatively less compared to that among women because of lower participation rate of young and middle aged men, who represent the major workforce in the community. This lower participation of men compounds the gender ratio of participants further in favour of females, from an already female -favourable ratio in the population.…”

Section: Discussionsupporting

confidence: 87%

Prevalence of peripheral artery disease in diabetes mellitus: research article

Tyagi¹,

Gupta²,

Bansal³

et al. 2017

Int J Res Med Sci

View full text Add to dashboard Cite

Background: Peripheral artery disease is a major macrovascular complication of diabetes mellitus. Patients with diabetes mellitus have an increased prevalence of PAD. The ankle brachial pressure index is an easy, non invasive and often under utilised tool for diagnosis of PAD.Methods: In the present study, 100 patients from Western Uttar Pradesh with diabetes mellitus were enrolled to find out prevalence of peripheral vascular disease using ankle brachial pressure index and study the associated risk factors.Results: 59 percent of the subjects were female and 41 percent were male. Ankle-brachial index (ABI) examination of patients indicated Abnormal (ABI= <0.9), in 40 cases.Conclusions: it can be concluded that peripheral vascular disease in Diabetes Mellitus is more commonly associated than is generally believed.

show abstract

Section: Discussionsupporting

confidence: 87%

Prevalence of peripheral artery disease in diabetes mellitus: research article

Tyagi¹,

Gupta²,

Bansal³

et al. 2017

Int J Res Med Sci

View full text Add to dashboard Cite

show abstract

“…2 Some of the studies done on native Indian people also show high prevalence of diabetes in urban areas. 3,4 Contribution of dietary practices and lifestyle factors are crucial, making incidence and prevalence of obesity and diabetes mellitus significantly more in the urban population. Recently, considerable concern has been caused by the increasing prevalence of diabetes in India, 5 particularly in the urban population.…”

Section: Introductionmentioning

confidence: 99%

High prevalence of diabetes, obesity and dyslipidaemia in urban slum population in northern India

et al. 2001

View full text Add to dashboard Cite

BACKGROUND AND AIMS:In this study, a prevalence survey of various atherosclerosis risk factors was carried out on hitherto poorly studied rural -urban migrants settled in urban slums in a large metropolitan city in northern India, with the aim of studying anthropometric and metabolic characteristics of this population in socio-economic transition. DESIGN: A cross-sectional epidemiological descriptive study. SUBJECTS: A total of 532 subjects (170 males and 362 females) were included in the study (response rate approximately 40%). METHODS AND RESULTS:In this study, diabetes mellitus was recorded in 11.2% (95% CI 6.8 -16.9) of males and 9.9% (95% CI 7.0 -13.5) of females, the overall prevalence being 10.3% (95% CI 7.8 -13.2). Based on body mass index (BMI), obesity was more prevalent in females (15.6%; 95% CI 10.7 -22.3) than in males (13.3%; 95% CI 8.5 -19.5). On the other hand, classifying obesity based on percentage body fat (%BF), 10.6% (95% CI 6.4 -16.2) of males and 40.2% (95% CI 34.9 -45.3) of females were obese. High waist -hip ratio (WHR) was observed in 9.4% (95% CI 5.4 -14.8) of males and 51.1% (95% CI 45.8 -56.3) of the females. All individual skinfolds and sum of skinfolds were significantly higher in females (P < 0.001). In both males and females above 30 y of age, there was a steep increase in the prevalence of high WHR, and in females, %BF was very high (particularly in %BF quartile > 30%). Furthermore, total cholesterol and low-density lipoprotein cholesterol were high in both males and females. Stepwise multiple linear regression analysis showed that for both males and females BMI, WHR and %BF were positive predictors of biochemical parameters, except for HDL-c, for which these parameters were negatively associated. CONCLUSIONS: Appreciable prevalence of obesity, dyslipidaemia, diabetes mellitus, substantial increase in body fat, generalised and regional obesity in middle age, particularly in females, need immediate attention in terms of prevention and health education in such economically deprived populations.

show abstract

“…This indicates the possibility of Type 2 diabetes sharing a genetic factor with FCPD. Alternatively, the association of the Class 3 allele with FCPD might represent the high background population prevalence of Type 2 diabetes amongst South Indians [49]. Some overlap of FCPD patients was seen who had both the Class 3 allele and DQ[3 T2 (13/64; 20%) compared to 1/80 (1%) of the control subjects (~2=12.6; p=0.0004).…”

Section: Discussionmentioning

confidence: 99%

The genetic predisposition to fibrocalculous pancreatic diabetes

et al. 1989

Self Cite

View full text Add to dashboard Cite

Summary. Fibrocalculous pancreatic diabetes (previously known as tropical pancreatic diabetes) is a rare cause of diabetes confined to countries within the tropical belt. The aetiology of fibrocalculous pancreatic diabetes is thought to be environmental although the agent(s) is unknown. We have investigated a possible genetic basis of this disease by looking for restriction fragment length polymorphisms of genes implicated in the aetiology of diabetes rnellitus. Seventy-six Dravidian patients with fibrocalculous pancreatic diabetes were studied, and the restriction fragment length polymorphisms obtained compared to racially matched control subjects (n=94), patients with Type2 (non-insulin-dependent) diabetes (n=87) and Type 1 (insulin-dependent) diabetes (n = 58). No association of fibrocalculous pancreatic diabetes was found with restriction fragment length polymorphisms of the insulin receptor gene. Although no association of fibrocalculous pancreatic diabetes was found with polymorphism of the HLA DRc~/DQc~/DXct genes, an association was found with the Taq 1 restriction fragment length polymorphisms of the DQ[~ gene (DQ[~ T2/T6 present in 39% of patients with fibrocalculous pancreatic diabetes compared to 19% in control subjects; p = 0.01 ; corrected p value = 0.04) which is similar to that found in Type 1 but not Type 2 diabetes. An association of fibrocalculous pancreatic diabetes was also found with the hypervariable region in the 5-prime flanking region of the insulin gene; 40% of patients possessed the class 3 allele compared to 9.5% of control subjects p = 0.0001 ; corrected p value = 0.0008). In Type 2 diabetes, similar results were obtained with 33% subjects possessing the class 3 allele (t7 value compared to control subjects = 0.0005; corrected p value = 0.004). This study suggests that fibrocalculous pancreatic diabetes has a genetic component in its aetiology. Furthermore, its origin might be related to an individual with part of the genetic predisposition to diabetes (Type 1 or Type 2) who additionally has evidence of chronic calcific pancreatitis.

show abstract

High prevalence of diabetes in an urban population in south India.

Cited by 186 publications

References 10 publications

Prevalence of peripheral artery disease in diabetes mellitus: research article

Prevalence of peripheral artery disease in diabetes mellitus: research article

High prevalence of diabetes, obesity and dyslipidaemia in urban slum population in northern India

The genetic predisposition to fibrocalculous pancreatic diabetes

Contact Info

Product

Resources

About