High prevalence of albuminuria in population-based patients diagnosed with type 2 diabetes in the Shanghai downtown

Lü, Bin; Wen, Jie; Song, Xiaoyan; Dong, Xuehong; Yang, Yehong; Zhang, Z.Y.; Zhao, Nai Qing; Ye, H.Y.; Mou, Bo; Chen, F.L.; Liu, Y.; Ye, Shen; Wang, X.C.; Zhou, Lei; Li, Y.M.; Zhu, Xiaopeng; Hu, Renming

doi:10.1016/j.diabres.2006.06.024

Cited by 45 publications

(28 citation statements)

References 38 publications

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“…Waist circumference was suggested to be associated with albumiunria in subjects with type 2 diabetes in Japan [18] and China [19]. The Funagata Study also confirmed positive associations between larger waist circumference defined by IDF with retinopathy after adjusting for other componentsin community-based population [10].…”

Section: Discussionmentioning

confidence: 77%

The Significance of Screening for Microvascular Diseases in Chinese Community-Based Subjects with Various Metabolic Abnormalities

et al. 2014

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BackgroundTo assess the association of albuminuria and retinopathy with metabolic syndrome (MetS) and the related metabolic components defined by various criteria in Chinese community-based subjects.MethodsA total of 3240 Chinese subjects were recruited from urban communities and classified into subgroups with isolated or concomitant state of the two microvascular diseases. MetS was defined according to the standard of International Diabetes Federation, the National Cholesterol Education Program's Adult Treatment Panel III and Chinese Diabetes Society (CDS), separately. Albuminuria was defined as an elevated morning urine albumin-to-creatinine ratio. Retinopathy were identified with nonmydriatic retinal photographs according to the Diabetic Retinopathy Disease Severity Scale. Logistic regression was performed to analyze the contributive risk factors.ResultsThe subgroup of isolated retinopathy was the oldest (P<0.05), with higher blood pressure (P<0.001) and larger waist circumference (P<0.05). After adjusting for age, sex and other metabolic components, individuals with blood pressure over 130/85 mmHg were prone to have isolated albuminuria (OR: 1.51, P = 0.0001); while individuals with fasting plasma glucose over 5.6 mmol/L were in high risk of retinopathy concomitant with albuminria (OR: 3.04, P = 0.006). Larger waist circumference was a potential risk factors for isolated albuminuria and isolated retinopathy, though not significant after further adjustment of other metabolic components. The risk for albuminuria and retinopathy increased with the aggregation of three or more metabolic components. However, the MetS per se did not have synergic effect and only the MetS defined by CDS remained as a risk factor.ConclusionsAlbuminuria and retinopathy were highly associated with accumulated metabolic abnormalities including sub-clinical elevated blood pressure and elevated fasting plasma glucose.

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Section: Discussionmentioning

confidence: 77%

The Significance of Screening for Microvascular Diseases in Chinese Community-Based Subjects with Various Metabolic Abnormalities

et al. 2014

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“…Concerning the screening methodology (two out of three determinations for the MAU diagnosis standard), the conditional probability approach provided an estimate for the Table 2 The comparison among micro-, macro-, and normoalbuminuria patients 9 In clinical practice, the estimated probability in Table 1 can be used to identify the highrisk MAU patients with noncompliant screening, because around 7.0% of patients may have negative result at the first screening followed by two positive results for MAU in the subsequent two screenings. Thus, it is still worth completing all three screening tests within 6 months when the first screening shows normoalbuminuria.…”

Section: Discussionmentioning

confidence: 99%

Justifying the high prevalence of microalbuminuria for type 2 diabetic patients in Taiwan with conditional probability approach—a DEMAND II Study☆

Chiang

Lee

Chen

et al. 2011

Journal of the Chinese Medical Association

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This study demonstrates the application of "conditional probability" method to justify the rationale of adopting two positive out of three urinary screening tests for the diagnosis of MAU. An adjusted prevalence rate of MAU as 26.9% is reported. These results may provide a basis for cost-benefit consideration in designing preventive and interventional policies in public health. Furthermore, the awareness and practice of early monitoring of MAU for DM patients should be strengthened.

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“…5 Although type 1 and type 2 DM both lead to ESRD, the majority of patients are those with type 2, due to the much greater prevalence. 6,7 Oman now has a total population of approximately 3.174 million, 8 of which 2.018 million are Omanis. The prevalence of DM is considered high (11.6%) in this country.…”

Section: Introductionmentioning

confidence: 99%

Prevalence and Risk Factors of Diabetic Nephropathy in Omani Type 2 Diabetics in Al-Dakhiliyah Region

Al-Rawahi¹,

Rizvi²,

Al-Riyami³

et al. 2012

Oman Med J

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High prevalence of albuminuria in population-based patients diagnosed with type 2 diabetes in the Shanghai downtown

Cited by 45 publications

References 38 publications

The Significance of Screening for Microvascular Diseases in Chinese Community-Based Subjects with Various Metabolic Abnormalities

The Significance of Screening for Microvascular Diseases in Chinese Community-Based Subjects with Various Metabolic Abnormalities

Justifying the high prevalence of microalbuminuria for type 2 diabetic patients in Taiwan with conditional probability approach—a DEMAND II Study☆

Prevalence and Risk Factors of Diabetic Nephropathy in Omani Type 2 Diabetics in Al-Dakhiliyah Region

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