High prevalence of abdominal aortic aneurysm in men with peripheral vascular disease: Screening by ultrasonography

Allardice, J. T.; Allwright, G. J.; Wafula, J. M. C.; Wyatt, A P

doi:10.1002/bjs.1800750318

Cited by 121 publications

(33 citation statements)

References 11 publications

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“…1 Data from large cross-sectional studies are consistent with the prospective data, supporting associations of AAA with male gender, age, cigarette smoking, serum cholesterol, and coexisting cardiovascular diseases. 3,11,31 A study of over 75 000 veterans ages 50 to 79 years identified 1031 AAA by ultrasound and reported associations with stature, serum cholesterol, and hypertension. A family history of aneurysm, reported by 5% of these veterans, was associated with a nearly 2-fold greater odds ratio.…”

Section: Discussionmentioning

confidence: 99%

“…Other studies, including the CHS, have reported a higher likelihood of other CVD among aneurysm patients. 1,6,8,31 Studies of children and young adults found associations of aortic (as well as coronary) plaque with lipid and glucose abnormalities, hypertension, and smoking. [33][34][35][36] It is not known whether such aortic lesions observed in youth are precursors of adult aneurysms.…”

Section: Discussionmentioning

confidence: 99%

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Middle Age Cardiovascular Risk Factors and Abdominal Aortic Aneurysm in Older Age

et al. 2003

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Abstract-Few prospective studies have examined associations between major cardiovascular risk factors and occurrence of abdominal aortic aneurysm; findings from cross-sectional studies are inconsistent. This long-term population-based study assessed relationships of major risk factors in middle-age to clinical nonfatal plus fatal abdominal aortic aneurysm in older-age in the Chicago Heart Association Detection Project in Industry cohort-10 574 men and 8700 women baseline ages 40 to 64 years screened for risk factors in 1967-1973 Key Words: abdominal aortic aneurysm Ⅲ risk factors Ⅲ prospective studies Ⅲ blood pressure Ⅲ cholesterol Ⅲ smoking C linical aortic aneurysm is an important cardiovascular disease in older people. Preclinical aneurysm development is insidious; co-morbidity complicates treatment of aneurysm whether it is discovered incidentally, by deliberate screening, or following an acute rupture. 1 Therefore prevention of this condition, via risk factor identification and treatment, is a pertinent clinical issue for older population strata. Much of the understanding of possibly modifiable risk for this disease of later life is derived from cross-sectional screening surveys and clinical series. [2][3][4][5][6][7][8][9][10][11] These studies have typically shown associations of such cardiovascular disease (CVD) risk factors as male gender, older age, and smoking with prevalent abdominal aortic aneurysm (AAA) and aneurysm progression. [2][3][4][5][6][7][8][9][10][11] Findings have been inconsistent, however, for hypertension, 6,9,12 serum cholesterol, 3,6,8,10 diabetes, 3,4,9 and such other possible risk factors as body habitus 3,9,13 and race. 3,4 There are relatively few prospective population studies on relationships of CVD risk factors to AAA, and these have been limited by paucity of risk factor data, short duration of follow-up, small number of cases leading to inclusion of all types of aortic aneurysms regardless of site. 14 -19 This report is from a long-term large population-based study on relationships of major modifiable CVD risk factors, measured in middle-aged employed persons, to CVD incidence and mortality in later life. It assesses prospectively relationships of risk factors to clinically identified nonfatal plus fatal AAA. Methods Study PopulationThe Chicago Heart Association (CHA) cohort consists of nearly 40 000 employed men and women screened for major cardiovascular risk factors from late 1967 to early 1973 at 84 work sites. Potential risk factors were determined by self-administered questionnaire for age, ethnicity, education, cigarette smoking, history of coronary heart disease (CHD), diagnosed diabetes, and high blood pressure. Standardized procedures were used to obtain height, weight, a single supine blood pressure, and a resting ECG. Major and minor ECG abnormalities were coded by Pooling Project criteria. 20 Blood was drawn to determine serum cholesterol and plasma glucose, measured 1 hour after a nonfasting 50-g oral glucose load. Participant recruitment and examination pr...

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Middle Age Cardiovascular Risk Factors and Abdominal Aortic Aneurysm in Older Age

et al. 2003

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“…In a group of male patients with peripheral arteriopathy, Allardice et a1. 29 reported that the incidence of AAA was 17%.…”

Section: Discussionmentioning

confidence: 99%

Routine Ultrasound Screening for Abdominal Aortic Aneurysm among 65- and 75-Year-Old Men in a City of 200,000 Inhabitants

Vázquez

Sakalihasan

D'Harcour

et al. 1998

Annals of Vascular Surgery

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Unruptured abdominal aortic aneurysm (AAA) is seldom recognized. Thus it is difficult to know whether the incidence of AAA in the general population is high enough to warrant routine screening at least in men after a certain age. Ultrasound screening studies to evaluate the incidence of AAA have been carried out in several English-speaking and Scandinavian countries. The purpose of this report is to describe the results of a study carried out in Belgium. All 65-and 75-year-old men living in the city of Liege, Belgium, were given the opportunity to undergo a free ultrasound examination. Only 41% of the target population was examined. AAA defined as abdominal aortic diameter of >30 mm was observed in 28 subjects (incidence: 3.8%).Mean abdominal aortic diameter was 34.7 mm. A diameter >29 mm was observed in 33 subjects (incidence 4.5%). Mean abdominal aortic diameter was 30.4 mm. On the basis of epidemiological data collected, a high-risk population for AAA was identified. Arterial hypertension (p < 0.05), previous coronary artery surgery ( p < 0.05), and smoking ( p < 0.06) were more common in subjects with than without AAA. The overall cost of screening was $18.175. The cost per AAA diagnosed was $551

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“…Abdominal aortic aneurysm is associated with atherosclerosis, with prevalence rates of 10% to 16% in patients known to have femoral occlusive disease. 13 It is also strongly associated with coronary artery disease; a recent study found that 36% of patients with known aortic aneurysm had severe coronary artery disease on angiography.…”

Section: Discussionmentioning

confidence: 99%

Coexistence of abdominal aortic aneurysm in patients with carotid stenosis.

Karanjia

Madden

Lobner

1994

Stroke

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Background and Purpose The study was designed to assess the incidence of coexistent abdominal aortic disease in patients with known carotid artery stenosis.Methods Abdominal ultrasound and physical examination of the abdomen were performed in 89 consecutive patients referred to this tertiary medical center for evaluation of both symptomatic and asymptomatic carotid artery disease. The frequency of abdominal aortic aneurysm detected in this population was compared with that incidentally found in ageand sex-matched patients undergoing abdominal ultrasound for nonvascular reasons.

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High prevalence of abdominal aortic aneurysm in men with peripheral vascular disease: Screening by ultrasonography

Cited by 121 publications

References 11 publications

Middle Age Cardiovascular Risk Factors and Abdominal Aortic Aneurysm in Older Age

Middle Age Cardiovascular Risk Factors and Abdominal Aortic Aneurysm in Older Age

Routine Ultrasound Screening for Abdominal Aortic Aneurysm among 65- and 75-Year-Old Men in a City of 200,000 Inhabitants

Coexistence of abdominal aortic aneurysm in patients with carotid stenosis.

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