High prevalence anti-Trypanosoma cruzi antibodies, among blood donors in the State of Puebla, a non-endemic area of Mexico

Abstract

Blood transfusion is the second most common transmission route of Chagas disease in many Latin

Epidemiology of Chagas disease in non endemic countries: the role of international migration

“…In 2004 however, screening coverage increased to 34%, and the prevalence for T. cruzi also increased to 5 per 1000 (PAHO 2006), the same prevalence found in the state of Veracruz (Ramos-Lingonio et al 2006). In some instances, information on rates of T. cruzi infection among blood donors from non endemic Mexican states (where there is no transmission) indicated high positive rates; such is the case of Puebla in 2001-2002 with a rate of 77 per 1000 (Sanchez Guillen et al 2002), or Mexico City in 1998-2000 with a rate of 68 per 1000 (Cabrera et al 2004). It was considered that the latter were mostly low income donors from 28 out of the 31 states of the country.…”

“…Human infection extends through North, Central, and South America, from Mexico in the north to Argentina and Chile in the south, affecting 21 countries (WHO 1991, 2002, OPS 2006.…”

“…Four countries screened 100% of donors for T.cruzi in 1993-19955, in 1997;7, in 2001-2002(Schmunis et al 1998, Schmunis & Cruz 2005and8, in 2004 (PAHO 2006). Another four countries screened ≥ 99% of donors in 2004 (PAHO 2006) (Table I).…”

Blood transfusion and iatrogenic risks in Mexico city: anti-Trypanosoma cruzi seroprevalence in 43,048 blood donors, evaluation of parasitemia, and electrocardiogram findings in seropositive

“…Almost thirty years after the first report predicting transfusion linked to T. cruzi infection (Pellegrino 1949), seropositive blood donors were recognized in Oaxaca, Mexico (Goldsmith & Kagan 1978), and several studies since then have shown a seropositive incidence varying between 0.2 to 17% in different regions of the country (Monteón et al 1987, Ramos-Echevarria et al 1993, Rodríguez-Felix et al 1995, Trujillo-Contreras et al 1995, Rangel et al 1998, Guzmán-Bracho et al 1998, Monteón-Padilla et al 1999, Sánchez-Guillen et al 2002. A wide survey was carried out in the national blood bank network, which included 64,969 samples collected in 18 Mexican states showed a seroprevalence varying between 0.2 and 2.8%, with a general mean of 1.6% (Guzman-Bracho et al 1998).…”

Triatoma gerstaeckeri (Hemiptera: Reduviidae) infectada con Trypanosoma cruzi en Nuevo León, México y patogenicidad de la cepa regional

“…American trypanosomiasis, or Chagas disease, is a major health problem in rural, urban, and suburban areas of the Americas (1). Few studies of Chagas disease have been conducted in northeastern México, which was considered free of Trypanosoma cruzi infection until 2009, because no reports of human cases were recorded.…”