2021
DOI: 10.1177/0956462421999287
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High prevalence and resistance rates of Mycoplasma genitalium among patients visiting two sexually transmitted infection clinics in the Netherlands

Abstract: Mycoplasma genitalium is a well-known cause of urethritis in men and has been associated with cervicitis, pelvic inflammatory disease, and adverse obstetric outcomes in women. In this cross-sectional study, we determined the current prevalence of M. genitalium infection and the rate of macrolide resistance in M. genitalium isolates, in patients visiting two large Dutch sexually transmitted infection (STI) clinics, to evaluate whether the recommendations in Dutch guidelines should be revised. In addition, risk … Show more

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Cited by 10 publications
(13 citation statements)
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“…Moreover, the resistance prevalence was significantly higher in men's anal samples (75.8%) versus other samples (54%) [ 23 ]. Recent studies in England and the Netherlands [ 24 , 25 ] highlight a prevalence of resistance to macrolides of 69% and 66%, respectively, in patients similar to patients in our study.…”
Section: Discussionsupporting
confidence: 85%
“…Moreover, the resistance prevalence was significantly higher in men's anal samples (75.8%) versus other samples (54%) [ 23 ]. Recent studies in England and the Netherlands [ 24 , 25 ] highlight a prevalence of resistance to macrolides of 69% and 66%, respectively, in patients similar to patients in our study.…”
Section: Discussionsupporting
confidence: 85%
“…This suggests that MG infection in urethritis is of less clinical importance in the presence of NG. Although asymptomatic MG infections are common, 13 it is striking that, in this symptomatic patient group, clinical treatment failure was so limited, considering the amount of MG coinfections found in the gonococcal urethritis cases in this study (19% [121 of 633]).…”
Section: Discussionmentioning
confidence: 79%
“… 12 , 13 Among the MG positive samples in the recent study, MG macrolide resistance-associated mutations (MRAM) was detected in 66%. 13 …”
mentioning
confidence: 99%
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