High pressure multiphase equilibria in aqueous systems of carbon dioxide, a hydrophilic organic solvent and biomolecules

Gas-Expanded Liquids

“…In many cases, including water/1-propanol at some temperatures, further phase transitions occur between these two key pressures, including the formation of a third liquid phase. , The pressures required are a function of the binary liquid mixture composition. This phase behavior has been reviewed in detail 13 The phase changes observed upon expanding a mixture of two miscible liquids past a lower critical solution pressure and an upper critical solution pressure. …”

High-pressure (vapour + liquid) equilibria in (carbon dioxide+ acetone or 2-propanol) at temperatures from 293 K to 333 K

“…The work is related to our interest in multiphase high-pressure (vapour + liquid + liquid) equilibria in (water + hydrophilic organic solvents + supercritical gases). (5)(6)(7)(8)(9)(10) Such equilibria are required for the design of new extraction processes such as bioseparations.…”

A novel high-pressure liquid-liquid extraction process for downstream processing in biotechnology: Extraction of cardiac glycosides

“…Some results for the partitioning of carbohydrates in the ternary system CO 2 + water + hydrophilic organic solvent have been reported by Pfohl et al (1996Pfohl et al ( , 1997. Recently, Adrian et al (1999) reported a set of experimental data for the partitioning of vanillin and caffeine on coexisting liquid phases in the ternary system CO 2 + water + acetone. This study extends that earlier work into the field of natural product separation.…”