High pressure and the origin of life

Hazen, Robert M.; Boctor, N. Z.; Brandes, Jay; Cody, George D.; Hemley, Russell J.; Sharma, Anurag; Yoder, H. S.

doi:10.1088/0953-8984/14/44/504

Cited by 47 publications

(38 citation statements)

References 55 publications

(50 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…[96][97][98][99] We have also failed to address the flourishing and fascinating area of the effect of pressure on biological reactions.B iological macromolecules and whole organisms persist and transform in interesting ways under substantial compression, whether near hydrothermal vents,d eep in crustal rocks,o rint he laboratory. [100][101][102][103] …”

Section: Other Approaches and Subjects That Remain Tomentioning

confidence: 99%

The Effect of Pressure on Organic Reactions in Fluids—a New Theoretical Perspective

2017

View full text Add to dashboard Cite

This Review brings a new perspective to the study of chemical reactions in compressed fluid media. We begin by reviewing the substantial insight gained from more than 50 years of experimental studies on organic reactions in solution under pressure. These led to a proper estimation of the critical roles of volume of activation (Δ≠V) and reaction volume (ΔV) in understanding pressure effect on rates and equilibria of organic reactions. A recently developed computational method, the XP‐PCM (extreme pressure polarizable continuum model) method, capable of carrying out quantum mechanical calculations of reaction pathways of molecules under pressure, is introduced. A case study of the Diels–Alder cycloaddition of cyclopentadiene with ethylene serves, in pedagogical detail, to describe the methodology. We then apply the XP‐PCM method to a selection of other pericyclic reactions, including the parent Diels–Alder cycloaddition of butadiene with ethylene, electrocyclic ring‐opening of cyclobutene, electrocyclic ring‐closing of Z‐hexatriene, the [1,5]‐H shift in Z‐pentadiene, and the Cope rearrangement. These serve as examples of some of the most common combinations of Δ≠V and ΔV. Interesting phenomena such as a shift in a transition state along a reaction coordinate, a switch of rate‐determining step, and the possible turning of a transition state into a stable minimum are revealed by the calculations. A reaction volume profile, the change in the volume of the reacting molecules as the reaction proceeds, emerges as being useful.

show abstract

Section: Other Approaches and Subjects That Remain Tomentioning

confidence: 99%

The Effect of Pressure on Organic Reactions in Fluids—a New Theoretical Perspective

2017

View full text Add to dashboard Cite

show abstract

“…Krzyzaniak et al (1994) found that Phe and Met can be specifically charged to their cognate tRNAs in the absence of enzymes at high pressure. Should this result be confirmed, then it shows that at least these two tRNAs are barophylic aptamers, which raises interesting thoughts in connection with the deep-sea hotspring scenario for the origin of life (reviewed by Hazen et al, 2002) and the need to select for extremophilic aptamers in general. Another odd result is that histidine and its anticodon GpUpG act similarly as catalysts in certain in vitro metabolic reactions (Shimizu, 2004).…”

Section: The Use Of Coenzymes: From the Rna World To The Protein Worlmentioning

confidence: 97%

Fitness Landscapes, Error Thresholds, and Cofactors in Aptamer Evolution

Kun

Maurel

Santos

et al. 2006

The Aptamer Handbook

View full text Add to dashboard Cite

“…at very low temperatures. Even under extreme magnetic fields >10 5 Tesla, a new kind of chemical bond (perpendicular paramagnetic bond) may exist, which may enable bonding of H 2 in the triplet state 2 .…”

Section: Introductionmentioning

confidence: 99%

“…4). A deeper understanding of the effect of pressure on these organisms could help us to understand the beginning of life on earth 5,6 . Subjecting matter to high pressure or low temperature, essentially results in a reduction of the inter-atomic distances.…”

Section: Introductionmentioning

confidence: 99%

High Pressure:One of the many Tools to Study Material Properties at Extreme Conditions

Garg¹

2017

Current Science

View full text Add to dashboard Cite

High pressure is a powerful and clean variable, which when applied can bring about large changes in structure and properties of materials. It can be used to simulate the conditions found deep inside the earth or in different planetary interiors. It is widely used in chemical industry, especially when the chemical reaction products have lower volumes than the initial reactants, and also in the food preservation industry, where it ensures that aromas and flavours are not lost even after preservation. Materials under pressure can be studied both theoretically and experimentally. In this article apart from discussing how to set up a basic high pressure experiment using the DAC, some examples have been elaborated to show how both experiments and theory complement each other and both put together can help in a deeper understanding of the changes brought about by application of high pressure.

show abstract

High pressure and the origin of life

Cited by 47 publications

References 55 publications

The Effect of Pressure on Organic Reactions in Fluids—a New Theoretical Perspective

The Effect of Pressure on Organic Reactions in Fluids—a New Theoretical Perspective

Fitness Landscapes, Error Thresholds, and Cofactors in Aptamer Evolution

High Pressure:One of the many Tools to Study Material Properties at Extreme Conditions

Contact Info

Product

Resources

About