High-precision compton imaging of 4.4 MeV prompt gamma-ray toward an on-line monitor for proton therapy

Mochizuki, Seibu; Kataoka, J.; Koide, A.; Fujieda, Kazuya; Maruhashi, Takuya; Kurihara, Takuya; Sueoka, Koki; Tagawa, Leo; Yoneyama, Masaki; Inaniwa, Taku

doi:10.1016/j.nima.2018.11.032

Cited by 21 publications

(11 citation statements)

References 7 publications

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“…Although ToF cannot be measured in the compact configuration, back-scattering gamma rays from the absorber are avoided using the energy cut of the scatterer. Various methods to reduce background contamination have been considered, and we successfully proved these methods could exclude the background events and improve the quality of the MeV gamma-ray images 20,21 .…”

Section: Introductionmentioning

confidence: 85%

“…The 3D-PSCC was originally developed for imaging MeV gamma rays in proton therapy 21 . The target energy band of the 3D-PSCC is from 300 keV to 5 MeV.…”

Section: Methodsmentioning

confidence: 99%

“…In this study, we used the prototype 3D-PSCC that was originally developed for MeV gamma-ray imaging in proton therapy 21 . To verify the performance of the prototype 3D-PSCC, we irradiated the camera with a MeV gamma-ray beam to mimic signals from celestial gamma-ray sources.…”

Section: Introductionmentioning

confidence: 99%

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Development and performance verification of a 3-D position-sensitive Compton camera for imaging MeV gamma rays

Hosokoshi

Kataoka

Mochizuki

et al. 2019

Sci Rep

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In gamma-ray astronomy, the 1–10 MeV range is one of the most challenging energy bands to observe owing to low photon signals and a considerable amount of background contamination. This energy band, however, comprises a substantial number of nuclear gamma-ray lines that may hold the key to understanding the nucleosynthesis at the core of stars, spatial distribution of cosmic rays, and interstellar medium. Although several studies have attempted to improve observation of this energy window, development of a detector for astronomy has not progressed since NASA launched the Compton Gamma Ray Observatory (CGRO) in 1991. In this work, we first developed a prototype 3-D position-sensitive Compton camera (3D-PSCC), and then conducted a performance verification at NewSUBARU, Hyogo in Japan. To mimic the situation of astronomical observation, we used a MeV gamma-ray beam produced by laser inverse Compton scattering. As a result, we obtained sharp peak images of incident gamma rays irradiating from incident angles of 0° and 20°. The angular resolution of the prototype 3D-PSCC was measured by the Angular Resolution Measure and estimated to be 3.4° ± 0.1° (full width at half maximum (FWHM)) at 1.7 MeV and 4.0° ± 0.5° (FWHM) at 3.9 MeV. Subsequently, we conceived a new geometry of the 3D-PSCC optimized for future astronomical observations, assuming a 50-kg class small satellite mission. The SΩ of the 3D-PSCC is 11 cm2sr, anticipated at 1 MeV, which is small but provides an interesting possibility to observe bright gamma-ray sources owing to the high intrinsic efficiency and large field of view (FoV).

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Section: Introductionmentioning

confidence: 85%

“…The 3D-PSCC was originally developed for imaging MeV gamma rays in proton therapy 21 . The target energy band of the 3D-PSCC is from 300 keV to 5 MeV.…”

Section: Methodsmentioning

confidence: 99%

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Development and performance verification of a 3-D position-sensitive Compton camera for imaging MeV gamma rays

Hosokoshi

Kataoka

Mochizuki

et al. 2019

Sci Rep

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“…Its angular resolution, measured at the FWHM, was approximately 8° at 662 keV. Since 2016, this group has been engaged in finding suitable methods to build a Compton camera for γ-ray imaging for particle therapy applications [ 122 , 123 , 124 ]. Kenichiro et al [ 125 ] also developed a Compton camera, namely a Compton–PET hybrid camera, based on Ce:GAGG detectors and demonstrated simultaneous imaging with 131 I and 18 F RI sources.…”

Section: Types Of Compton Camerasmentioning

confidence: 99%

“…The study results could not confirm whether the 718 keV peak traces the Bragg peak. Subsequently, a 3D position-sensitive Ce:GAGG Compton camera was used to measure the 4.4 MeV prompt γ-ray energy range due to the 70 MeV proton beam on a PMMA phantom [ 123 ]. The improved Compton camera had an angular resolution of 5 degrees FWHM at 4.4 MeV and was able to discriminate multiple-Compton and escape events, which were the factors for background noises.…”

Section: Applications Of Compton Camerasmentioning

confidence: 99%

Development and Applications of Compton Camera—A Review

Parajuli

Sakai

Parajuli³

et al. 2022

Sensors

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The history of Compton cameras began with the detection of radiation sources originally for applications in astronomy. A Compton camera is a promising γ-ray detector that operates in the wide energy range of a few tens of keV to MeV. The γ-ray detection method of a Compton camera is based on Compton scattering kinematics, which is used to determine the direction and energy of the γ-rays without using a mechanical collimator. Although the Compton camera was originally designed for astrophysical applications, it was later applied in medical imaging as well. Moreover, its application in environmental radiation measurements is also under study. Although a few review papers regarding Compton cameras have been published, they either focus very specifically on the detectors used in such cameras or the particular applications of Compton cameras. Thus, the aim of this paper is to review the features and types of Compton cameras and introduce their applications, associated imaging algorithms, improvement scopes, and their future aspects.

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