We have developed and commercialized novel polyurethane (PU) with high elasticity and durability based on a cycloaliphatic diisocyanate controlled the stereoisomer structure. The diisocyanate is called FORTIMO TM trans-1,4-bis (isocyanatomethyl) cyclohexane (1,4-H 6 XDI). FORTIMO TM 1,4-H 6 XDI controlled with high trans isomer structure forms a well-organized hard segment phase. Therefore a micro-phase separation structure between soft segment and hard segment phases is progressed, resulting in an improved elasticity and heat resistance of PU elastomer. In addition, the light stability for long term of this PU is excellent due to an aliphatic structure. FORTIMO TM 1,4-H 6 XDI based PU achieve superior elasticity and durability which was not able to be realized with the existing diisocyanate. FORTIMO TM 1,4-H 6 XDI is applicable to various PUs, for example, not only thermoplastic, thermoset PU elastomers, but also water dispersed PU, micro-cellar and flexible PU foam with these advantages. This paper will describe the concept and examples of application of FORTIMO TM PU to industry.