High-performance liquid chromatography with peroxyoxalate chemiluminescence determination of propentofylline concentrations in rat brain microdialysate

Hamachi, Yozo; Nakashima, Mihoko N.; Nakashima, Kenichiro

doi:10.1016/s0378-4347(98)00587-8

Cited by 11 publications

(10 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…DBD-H was used for the detemination of short-chain aliphatic aldehydes (Nakashima et al, 1994), 17-oxosteroids derivatives , 20-oxosteroids derivatives and their sulfates and choline glycerophospholipids (Ou et al, 1995). The derivatives with DBD-H were suitable for the peroxyoxalate chemiluminescence detection, and therefore DBD-H was used for the determination of medroxyprogesterone acetate , long chain aliphatic aldehydes (Nakashima et al, 1996) and propentofylline (Hamachi et al, 1999).…”

Section: For Carboxylic Acids Nbd-pzmentioning

confidence: 99%

Fluorogenic and fluorescent labeling reagents with a benzofurazan skeleton

Uchiyama

Santa

Okiyama

et al. 2001

Biomedical Chromatography

151

101

View full text Add to dashboard Cite

Fluorogenic and fluorescent labeling reagents having a benzofurazan (2,1,3-benzoxadiazole) skeleton such as 4-fluoro-7-nitro-2,1,3-benzoxadiazole (NBD-F), 4-N,N-dimethylaminosulfonyl-7-fluoro-2,1,3-benzoxadiazole (DBD-F), 4-aminosulfonyl-7-fluoro-2,1,3-benzoxadiazole (ABD-F), ammonium 7-fluoro-2,1,3-benzoxadiazole-4-sulfonate (SBD-F), 4-hydrazino-7-nitro-2,1,3-benzoxadiazole (NBD-H), 4-N,N-dimethylaminosulfonyl-7-hydrazino-2,1,3-benzoxadiazole (DBD-H), 4-nitro-7-N-piperazino-2,1,3-benzoxadiazole (NBD-PZ), 4-N,N-dimethylaminosulfonyl-7-N-piperazino-2,1,3-benzoxadiazole (DBD-PZ), 4-(N-chloroformylmethyl-N-methyl)amino-7-N,N-dimethylaminosulfonyl-2,1,3-benzoxadiazole (DBD-COCl) and 7-N,N-dimethylaminosulfonyl-4-(2,1,3-benzoxadiazolyl) isothiocyanate (DBD-NCS) are reviewed in terms of synthetic method, reactivity, fluorescence characteristics, sensitivity and application to analytes.

show abstract

Section: For Carboxylic Acids Nbd-pzmentioning

confidence: 99%

Fluorogenic and fluorescent labeling reagents with a benzofurazan skeleton

Uchiyama

Santa

Okiyama

et al. 2001

Biomedical Chromatography

151

101

View full text Add to dashboard Cite

show abstract

“…The CL spectra produced from these reactions could be used for different analytical applications, based on the determination of fluorophores, peroxides , catalysts or quenchers used in the PO-CL system. Such multi-scope character of the PO-CL systems enables them to be employed as powerful analytical tools for the detection of a wide variety of analytes such as hydrogen peroxide [3,4], fluorescent compounds [5,6], catecholamines [7,8], carboxylic acids [9], carbonyl compounds [10], amines [11,12] and amino acids [13].…”

Section: Introductionmentioning

confidence: 99%

Peroxyoxalate-chemiluminescence of Tinopal CBS as a commercially important optical brightener: Mechanistic study and quantification

Shamsipur

Zargoosh

Chaichi

et al. 2010

Journal of Luminescence

View full text Add to dashboard Cite

“…Furthermore, DBD moiety was found to be efficiently excited by PO-CL reaction. 13 Based on this fact, medroxyprogesterone acetate, 14 long-chain aliphatic aldehydes 15 and propentofylline 16 labeled with DBD-H could be sensitively determined by PO-CL detection. Figure 3 shows the chromatograms of DBD-hydrazones of 8 aliphatic aldehydes obtained by PO-CL detection with bis(2,4,6-trichlorophenyl)oxalate (TCPO) and hydrogen peroxide as CL reagents.…”

Section: ·1 Bezoxadiazole Derivatives 11-21mentioning

confidence: 99%

Analytical Studies on the Development of High-Performance Liquid Chromatographic Methods with Fluorescence or Chemiluminescence Detections and Their Practical Applications

2009

Self Cite

View full text Add to dashboard Cite

This review describes a comprehensive investigation focusing on syntheses of analytical reagents, followed by their utilization in development of analytical methods, and leading to practical applications for rational use of medicaments centering on abused drugs. Many kinds of analytical reagents for fluorescence and chemiluminescence detections have been synthesized with the intention of improving sensitivity. By properly combining the developed analytical reagents with an HPLC separation technique, one could determine ultra-small amounts of abused drugs such as stimulants, narcotics and obesity drugs in various matrices. Furthermore, chiral analyses of some abused drugs and evaluation of their potential for drug-drug interaction were also performed. The developed methods might be useful for forensic and toxicological studies on drug abuse. Also, the results obtained in our study might contribute to the prediction of and the protection of human health from risks of abused drugs.

show abstract

High-performance liquid chromatography with peroxyoxalate chemiluminescence determination of propentofylline concentrations in rat brain microdialysate

Cited by 11 publications

References 8 publications

Fluorogenic and fluorescent labeling reagents with a benzofurazan skeleton

Fluorogenic and fluorescent labeling reagents with a benzofurazan skeleton

Peroxyoxalate-chemiluminescence of Tinopal CBS as a commercially important optical brightener: Mechanistic study and quantification

Analytical Studies on the Development of High-Performance Liquid Chromatographic Methods with Fluorescence or Chemiluminescence Detections and Their Practical Applications

Contact Info

Product

Resources

About