High-performance liquid chromatography of naphthylurethanes with fluorescence detection

Wintersteiger, Reinhold; Wenninger-Weinzierl, G.; Pacha, W.

doi:10.1016/s0021-9673(00)97626-x

Cited by 25 publications

(5 citation statements)

References 6 publications

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“…This method allows for detection of the distribution of the end-groups across the chromatogram. The original methodology was shown by Wintersteiger et al 27 and worked very well for OH groups indication by liquid chromatography.…”

Section: Resultsmentioning

confidence: 99%

Aromatic−Aliphatic Polyesters with Tailored Degree of Branching Based on AB/AB₂and ABB*/AB₂Monomers

Khalyavina

Schallausky²,

Komber

et al. 2010

Macromolecules

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The synthesis and characterization of aromatic−aliphatic polyesters with tailored degree of branching (DB), i.e. hyperbranched (hb), gradually branched, and linear polymers, are described. The dilute solution properties of polymers resulting from two different synthetic approaches are compared. The ABB*/AB2 approach leads to homopolymers with different DB based on the same AB2 monomer, 4,4-bis(4′-hydroxyphenyl)pentanoic acid, employing the protection of one phenolic group (B*) in the AB2 monomer followed by copolymerization with AB2 monomer at different molar ratios. Because of their identical chemical origin, well-tunable DB, comparable molar masses, an absence of aggregation in common solvents, and high refractive index increments, they are suitable as model systems in branching characterization. Their solution properties are compared to those of polymers obtained by the AB/AB2 approach. In order to study the influence of the end-groups on thermal and solution polymer properties, all terminal OH groups were modified with tert-butyldimethylsilyl chloride (SY-Cl). A different dependence of the thermal properties on branching was found for OH- and SY-terminated samples produced by the ABB*/AB2 approach. While the difference in the T g values between linear and hb structures was found to be 16 °C for SY-terminated samples, nearly identical values were obtained for OH-terminated linear and hb polyesters due to strong effect of hydrogen bond formation.

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Section: Resultsmentioning

confidence: 99%

Aromatic−Aliphatic Polyesters with Tailored Degree of Branching Based on AB/AB₂and ABB*/AB₂Monomers

Khalyavina

Schallausky²,

Komber

et al. 2010

Macromolecules

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“…(Wintersteiger and Wenningerweinzierl, 1981; Wintersteiger et al. , 1982) and applied in the sequel by several authors. In a previous paper we described an enantioselective HPLC method for sympathomimetics as their fluorescent urea derivatives after reaction of NIC with their amine functions on a cellulose tris(3,5‐dimethylphenylcarbamate) coated silica gel column (Chiracel OD‐RH) (Ullrich et al.…”

Section: Introductionmentioning

confidence: 99%

Chiral separation of the β₂‐sympathomimetic fenoterol by HPLC and capillary zone electrophoresis for pharmacokinetic studies

Ullrich

Wesenberg

Bleuel

et al. 2010

Biomedical Chromatography

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The development of methods for the separation of the enantiomers of fenoterol by chiral HPLC and capillary zone electrophoresis (CZE) is described. For the HPLC separation precolumn fluorescence derivatization with naphthyl isocyanate was applied. The resulting urea derivatives were resolved on a cellulose tris(3,5-dimethylphenylcarbamate)-coated silica gel column employing a column switching procedure. Detection was carried out fluorimetrically with a detection limit in the low ng/mL range. The method was adapted to the determination of fenoterol enantiomers in rat heart perfusates using liquid-liquid extraction. As an alternative a CE method was used for the direct separation of fenoterol enantiomers comparing different cyclodextrin derivatives as chiral selectors.

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“…PPDA, which has a primary and a tertiary amino group as well as two primary hydroxyl functions appropriate for derivatization, was transformed into highly fluorescent derivatives by naphthyl isocyanate NI and MBP. Both reagents had been successfully introduced in the early 1980s for the fluorometric determination of alcoholic compounds [6][7][8][9] .…”

Section: Derivatizationmentioning

confidence: 99%

Determination of a Hair Dye Using Different Derivatization Agents and HPLC in Combination with UV, Electrochemical, and Fluorescence Detection

Goger

Wintersteiger²,

Beck³

1999

Arch. Pharm. Pharm. Med. Chem.

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High-performance liquid chromatography of naphthylurethanes with fluorescence detection

Cited by 25 publications

References 6 publications

Aromatic−Aliphatic Polyesters with Tailored Degree of Branching Based on AB/AB₂and ABB*/AB₂Monomers

Aromatic−Aliphatic Polyesters with Tailored Degree of Branching Based on AB/AB₂and ABB*/AB₂Monomers

Chiral separation of the β₂‐sympathomimetic fenoterol by HPLC and capillary zone electrophoresis for pharmacokinetic studies

Determination of a Hair Dye Using Different Derivatization Agents and HPLC in Combination with UV, Electrochemical, and Fluorescence Detection

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High-performance liquid chromatography of naphthylurethanes with fluorescence detection

Cited by 25 publications

References 6 publications

Aromatic−Aliphatic Polyesters with Tailored Degree of Branching Based on AB/AB2and ABB*/AB2Monomers

Aromatic−Aliphatic Polyesters with Tailored Degree of Branching Based on AB/AB2and ABB*/AB2Monomers

Chiral separation of the β2‐sympathomimetic fenoterol by HPLC and capillary zone electrophoresis for pharmacokinetic studies

Determination of a Hair Dye Using Different Derivatization Agents and HPLC in Combination with UV, Electrochemical, and Fluorescence Detection

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Aromatic−Aliphatic Polyesters with Tailored Degree of Branching Based on AB/AB₂and ABB*/AB₂Monomers

Aromatic−Aliphatic Polyesters with Tailored Degree of Branching Based on AB/AB₂and ABB*/AB₂Monomers

Chiral separation of the β₂‐sympathomimetic fenoterol by HPLC and capillary zone electrophoresis for pharmacokinetic studies