High-performance liquid chromatographic determination of vitamin D3 in fish liver oils and eel body oils.

Takeuchi, Atsuko; Okano, Toshio; Ayame, Mari; Yoshikawa, Harumi; Teraoka, Sumiko; Murakami, Yumiko; Kobayashi, Tadashi

doi:10.3177/jnsv.30.421

Cited by 38 publications

(12 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is still the fish liver oil that contains the highest amounts of vitamin D 3 . The highest reported concentration was found in skipjack liver oil 144,400 μg/100 g (Takeuchi et al, 1984). The fish liver oils besides other nutritional ingredients might contain high levels of vitamin A.…”

Section: Vitamin D Part Of Nutrition and Content In Foodsmentioning

confidence: 99%

Vitamin D: a critical and essential micronutrient for human health

Bendik¹,

Friedel²,

Roos³

et al. 2014

Front. Physiol.

184

140

View full text Add to dashboard Cite

Vitamin D is a micronutrient that is needed for optimal health throughout the whole life. Vitamin D3 (cholecalciferol) can be either synthesized in the human skin upon exposure to the UV light of the sun, or it is obtained from the diet. If the photoconversion in the skin due to reduced sun exposure (e.g., in wintertime) is insufficient, intake of adequate vitamin D from the diet is essential to health. Severe vitamin D deficiency can lead to a multitude of avoidable illnesses; among them are well-known bone diseases like osteoporosis, a number of autoimmune diseases, many different cancers, and some cardiovascular diseases like hypertension are being discussed. Vitamin D is found naturally in only very few foods. Foods containing vitamin D include some fatty fish, fish liver oils, and eggs from hens that have been fed vitamin D and some fortified foods in countries with respective regulations. Based on geographic location or food availability adequate vitamin D intake might not be sufficient on a global scale. The International Osteoporosis Foundation (IOF) has collected the 25-hydroxy-vitamin D plasma levels in populations of different countries using published data and developed a global vitamin D map. This map illustrates the parts of the world, where vitamin D did not reach adequate 25-hydroxyvitamin D plasma levels: 6.7% of the papers report 25-hydroxyvitamin D plasma levels below 25 nmol/L, which indicates vitamin D deficiency, 37.3% are below 50 nmol/Land only 11.9% found 25-hydroxyvitamin D plasma levels above 75 nmol/L target as suggested by vitamin D experts. The vitamin D map is adding further evidence to the vitamin D insufficiency pandemic debate, which is also an issue in the developed world. Besides malnutrition, a condition where the diet does not match to provide the adequate levels of nutrients including micronutrients for growth and maintenance, we obviously have a situation where enough nutrients were consumed, but lacked to reach sufficient vitamin D micronutrient levels. The latter situation is known as hidden hunger. The inadequate vitamin D status impacts on health care costs, which in turn could result in significant savings, if corrected. Since little is known about the effects on the molecular level that accompany the pandemic like epigenetic imprinting, the insufficiency-triggered gene regulations or the genetic background influence on the body to maintain metabolic resilience, future research will be needed. The nutrition community is highly interested in the molecular mechanism that underlies the vitamin D insufficiency caused effect. In recent years, novel large scale technologies have become available that allow the simultaneous acquisition of transcriptome, epigenome, proteome, or metabolome data in cells of organs. These important methods are now used for nutritional approaches summarized in emerging scientific fields of nutrigenomics, nutrigenetics, or nutriepigenetics. It is believed that with the help of these novel concepts further understanding can be generated to develop f...

show abstract

Section: Vitamin D Part Of Nutrition and Content In Foodsmentioning

confidence: 99%

Vitamin D: a critical and essential micronutrient for human health

Bendik¹,

Friedel²,

Roos³

et al. 2014

Front. Physiol.

184

140

View full text Add to dashboard Cite

show abstract

“…Those that do exist have demonstrated that teleosts, unlike other vertebrates, have large hepatic stores of this vitamin [9], the highest concentrations being found in the livers of marine fish [10]. Although physiological studies have suggested a role for the vD 3 system in teleosts similar to that in other vertebrates [11][12][13][14], it has been speculated that the functions of this vitamin in fish may differ from its known classical functions in terrestrial animals [15].…”

Section: Introductionmentioning

confidence: 99%

Effects of dietary vitamin D3 administration on innate immune parameters of seabream (Sparus aurata L.)

Cerezuela

Cuesta

Meseguer

et al. 2009

Fish & Shellfish Immunology

View full text Add to dashboard Cite

“…Genistein is an isoflavone found in high quantities in serum after ingestion of a soy-rich meal and has been demonstrated to have potent inhibitory actions on prostate and breast tumor growth in mice (4). 1,25-Dihydroxyvitamin D 3 [1,25(OH) 2 D 3 ], the active metabolite of vitamin D 3 , is primarily obtained from endogenous synthesis and from dietary sources such as ocean fish oils (5). The growth-inhibitory actions of 1,25(OH) 2 D 3 are mediated by the nuclear vitamin D receptor [VDR (6,7)].…”

Section: Introductionmentioning

confidence: 99%