High performance indium oxide nanoribbon FETs: mitigating devices signal variation from batch fabrication

Pham, Thuy T.; Tran, Duy Phu; Thierry, Benjamin

doi:10.1039/c9na00592g

Cited by 6 publications

(9 citation statements)

References 56 publications

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“…The indium oxide nanoribbon FET sensors were fabricated as previously described and integrated within the 3D-printed fluidic device. 5,6 All FET measurements were performed using a Keysight Precision Source/Measure Unit B2900A Series (Keysight Technologies, USA). The data were recorded and…”

Section: ■ Experimental Sectionmentioning

confidence: 99%

“…Advances in biosensing technologies are paving the way to the feasibility of performing advanced bioanalytical assays in PoC settings. Among the various biosensing technologies relevant to PoC testing, label-free electrical biosensors, especially those based on nanoscale field-effect transistors (FETs), present significant advantages including ultrahigh sensitivity (typically in the sub-picomolar range), , fast and quantitative measurement capability (in the order of minutes), direct signal transduction, low power consumption, and compatibility with the multiplexed analyte measurement as well as on-chip sample processing and integration. − These features suggest the feasibility of FET sensor-based PoC testing with high diagnostic accuracy, reduced complexity, increased portability, and acceptable cost. , …”

Section: Introductionmentioning

confidence: 99%

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Integrated Platform Addressing the Finger-Prick Blood Processing Challenges of Point-of-Care Electrical Biomarker Testing

et al. 2022

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Continued advances in label-free electrical biosensors pave the way to simple, rapid, cost-effective, high-sensitivity, and quantitative biomarker testing at the point-of-care setting that would profoundly transform healthcare. However, implementation in routine diagnostics is faced with significant challenges associated with the inherent requirement for biofluid sample processing before and during testing. We present here a simple yet robust autonomous finger-prick blood sample processing platform integrated with nanoscale field-effect transistor biosensors and demonstrate the feasibility of measuring the SARS-CoV-2 nucleocapsid protein. The 3Dprinted platform incorporates a high-yield blood-to-plasma separation module and a delay valve designed to terminate the assay at a specific time. The platform is driven by hydrostatic pressure to efficiently and automatically dispense plasma and washing/measurement buffer to the nanosensors. Our model study demonstrates the feasibility of detecting down to 1.4 pg/mL of the SARS-CoV-2 nucleocapsid protein within 25 min and with only minimal operator intervention.

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Section: ■ Experimental Sectionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Integrated Platform Addressing the Finger-Prick Blood Processing Challenges of Point-of-Care Electrical Biomarker Testing

et al. 2022

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“…Indium (III) oxide (In 2 O 3 ) and tin-doped indium oxide (ITO) have been addressed as an interested field recently [ 283 , 284 , 285 ]. Both the In 2 O 3 and ITO materials exhibit metal-like behaviors.…”

Section: Other Fetsmentioning

confidence: 99%

Ten Years Progress of Electrical Detection of Heavy Metal Ions (HMIs) Using Various Field-Effect Transistor (FET) Nanosensors: A Review

et al. 2021

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Heavy metal pollution remains a major concern for the public today, in line with the growing population and global industrialization. Heavy metal ion (HMI) is a threat to human and environmental safety, even at low concentrations, thus rapid and continuous HMI monitoring is essential. Among the sensors available for HMI detection, the field-effect transistor (FET) sensor demonstrates promising potential for fast and real-time detection. The aim of this review is to provide a condensed overview of the contribution of certain semiconductor substrates in the development of chemical and biosensor FETs for HMI detection in the past decade. A brief introduction of the FET sensor along with its construction and configuration is presented in the first part of this review. Subsequently, the FET sensor deployment issue and FET intrinsic limitation screening effect are also discussed, and the solutions to overcome these shortcomings are summarized. Later, we summarize the strategies for HMIs’ electrical detection, mechanisms, and sensing performance on nanomaterial semiconductor FET transducers, including silicon, carbon nanotubes, graphene, AlGaN/GaN, transition metal dichalcogenides (TMD), black phosphorus, organic and inorganic semiconductor. Finally, concerns and suggestions regarding detection in the real samples using FET sensors are highlighted in the conclusion.

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Section: Metal Oxidesmentioning

confidence: 99%

“…FET NW-based sensors have attracted attention in chemical and biological sensing due to their high sensitivity, capability for direct (label-free) signal transduction and point-of-care integration. 207 Semiconducting metal oxides, especially In 2 O 3 , ZnO, β-Bi 2 O 3 and ITO, have been widely studied as FET sensors. Recent work has focused on improving device performance and more scalable fabrication, such as the use of chemical lift-off lithography, shadow mask patterning, and photochemical activation with UV light.…”

Section: ■ Metal Oxidesmentioning

confidence: 99%

Sensors Based Upon Nanowires, Nanotubes, and Nanoribbons: 2016–2020

et al. 2020

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Abbreviations: LOD = limit of detection, BP = black phosphorus, NRs = nanoribbons, CNT = carbon nanotubes, AAO = anodic aluminum oxide, HT = hydrothermal synthesis, CVD = chemical vapor deposition, OTS = octadecyltrichlorosilane, DEP = dielectrophoresis, CR = chemiresistive, AM = amperometric, FET = field-effect transistor, AQP4 = aquaporin-4, HER2 = human epidermal growth factor receptor 2, PSA = prostatespecific antigen, NPY = neuropeptide Y, DHEAS = dehydroepiandrosterone sulfate, HCHO = formaldehyde, THC = tetrahydrocannabinol, N/A = information not available, and τ res / τ rec = reported or estimated response time/recovery time.

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High performance indium oxide nanoribbon FETs: mitigating devices signal variation from batch fabrication

Abstract: High performance indium oxide nanoribbon FETs: mitigating device-to-device signal variation in the subthreshold regime.

Cited by 6 publications

References 56 publications

Integrated Platform Addressing the Finger-Prick Blood Processing Challenges of Point-of-Care Electrical Biomarker Testing

Integrated Platform Addressing the Finger-Prick Blood Processing Challenges of Point-of-Care Electrical Biomarker Testing

Ten Years Progress of Electrical Detection of Heavy Metal Ions (HMIs) Using Various Field-Effect Transistor (FET) Nanosensors: A Review

Sensors Based Upon Nanowires, Nanotubes, and Nanoribbons: 2016–2020

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