“…Using proximity ligation or DNA-based aptamers to capture protein targets of interest, respectively, both assays can measure thousands of proteins of varying abundance from a small biofluid sample. Recent studies have demonstrated the ability of these techniques to uncover cancer-related proteomic signals 220 – 222 . Compared to ctDNA, liquid biopsy proteomics and transcriptomics are early in their development, but recent advances suggest that these analytes may also play a more prominent role in the field in the future.…”