High molecular weight persimmon tannin ameliorates cognition deficits and attenuates oxidative damage in senescent mice induced by d-galactose

Tian, Yun; Zou, Bo; Yang, Li; Xu, Shengyu; Yang, Jie; Yao, Ping; Li, Chunmei

doi:10.1016/j.fct.2011.04.018

Cited by 64 publications

(42 citation statements)

References 49 publications

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“…SOD is one of the main antioxidant enzymes and can catalyze O 2− disproportionately into H 2 O 2 and O 2 . Reduction of SOD activity may increase peroxide which is followed by changes in molecular structure resulting in cell destruction (Tian et al, 2011). The results from the current study show that taurine supplementation may increase SOD activity and T-AOC levels in kidney tissue in three poultry rearing systems.…”

Section: Discussionmentioning

confidence: 54%

Effects of taurine and housing density on renal function in laying hens

Zhi-gang

Gao

et al. 2016

J. Zhejiang Univ. Sci. B

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This study investigated the putative protective effects of supplemental 2-aminoethane sulfonic acid (taurine) and reduced housing density on renal function in laying hens. We randomly assigned fifteen thousand green-shell laying hens into three groups: a free range group, a low-density caged group, and a high-density caged group. Each group was further divided equally into a control group (C) and a taurine treatment group (T). After 15 d, we analyzed histological changes in kidney cells, inflammatory mediator levels, oxidation and anti-oxidation levels. Experimental data revealed taurine supplementation, and rearing free range or in low-density housing can lessen morphological renal damage, inflammatory mediator levels, and oxidation levels and increase anti-oxidation levels. Our data demonstrate that taurine supplementation and a reduction in housing density can ameliorate renal impairment, increase productivity, enhance health, and promote welfare in laying hens.

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Section: Discussionmentioning

confidence: 54%

Effects of taurine and housing density on renal function in laying hens

Zhi-gang

Gao

et al. 2016

J. Zhejiang Univ. Sci. B

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“…Studies showed that there were decreases in ACh, ChAT and AChE expression in brain of mice subjected to harmful substances (Jamal et al, 2007;Liang et al, 2010). However, ChAT and AChE levels were increased in other studies (Espinosa et al, 2011;Tian et al, 2011). The up or down regulations of ACh, ChAT and AChE are all caused by stimulation from toxic substances.…”

Section: Discussionmentioning

confidence: 87%

Potential mechanisms of neurobehavioral disturbances in mice caused by sub-chronic exposure to low-dose VOCs

Fan¹,

Li²,

Liu³

et al. 2014

Inhalation Toxicology

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To investigate effects of neurobehavioral disturbances in mice caused by sub-chronic exposure to low-dose volatile organic compounds (VOCs) and the possible mechanism for these effects, 60 male Kunming mice were exposed in 5 similar static chambers, 0 (control) and 4 different doses of VOCs mixture (G1-4) for consecutively 90 d at 2 h/d. The concentrations of VOCs mixture were as follows: formaldehyde, benzene, toluene, and xylene 0.05 + 0.05 + 0.10 + 0.10 mg/m(3), 0.10 + 0.11 + 0.20 + 0.20 mg/m(3), 0.50 + 0.55 + 1.00 + 1.00 mg/m(3), 1.00 +1.10 + 2.00 + 2.00 mg/m(3), respectively, which corresponded to 1/2, 1, 5, and 10 times of indoor air quality standard in China. Morris water maze (MWM) and Grip strength (GS) test were performed in the last 7 weeks. One day following VOCs exposure, oxidative stress markers, neurotransmitters, and cholinergic system enzymes in brain were examined. In addition, the expressions of N-methyl-d-aspartate (NMDA) receptor in hippocampus were determined. VOCs exposure induced behavioral impairment of mice in MWM and GS test. The levels of reactive oxygen species (ROS), malondialdehyde (MDA) and glutamic acid (Glu) were significantly increased, while the acetylcholinesterase (AChE), choline acetyltransferase (ChAT) and acetylcholine (ACh) levels, and the expression of NMDA receptor were significantly decreased in VOCs exposed groups. Results showed that sub-chronic exposure to low-dose VOCs induced damage on physique and motor function, as well as impairment on learning and memory capacity of mice. Oxidative damage, abnormal metabolism of neurotransmitters and cholinergic system enzymes, and the alternation of NMDA receptor expression may be the possible mechanism for VOCs-induced neurotoxicity.

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“…T-AOC levels reflect the activity of scavenging free radicals (Lewis et al, 1995). SOD can catalyze O 2 − disproportionately into H 2 O 2 and O 2 (Lewis et al, 1995;Tian et al, 2011). MDA is a product of lipid peroxidation, which is often used as a bio-marker of tissue oxidative stress and cell damage (Parikh et al, 2003;Wu et al, 2012).…”

Section: Discussionmentioning

confidence: 99%

Influence of dietary taurine and housing density on oviduct function in laying hens

Dai

Zhang

Zhi-gang

et al. 2015

J. Zhejiang Univ. Sci. B

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Experiments were conducted to study the effects of dietary taurine and housing density on oviduct function in laying hens. Green-shell laying hens were randomly assigned to a free range group and two caged groups, one with low-density and the other with high-density housing. Each group was further divided into control (C) and taurine treatment (T) groups. All hens were fed the same basic diet except that the T groups' diet was supplemented with 0.1% taurine. The experiment lasted 15 d. Survival rates, laying rates, daily feed consumption, and daily weight gain were recorded. Histological changes, inflammatory mediator levels, and oxidation and anti-oxidation levels were determined. The results show that dietary taurine supplementation and reduced housing density significantly attenuated pathophysiological changes in the oviduct. Nuclear factor-κB (NF-κB) DNA binding activity increased significantly in the high-density housing group compared with the two other housing groups and was reduced by taurine supplementation. Tumor necrosis factor-α (TNF-α) mRNA expression in the high-density and low-density C and T groups increased significantly. In the free range and low-density groups, dietary taurine significantly reduced the expression of TNF-α mRNA. Supplementation with taurine decreased interferon-γ (IFN-γ) mRNA expression significantly in the low-density groups. Interleukin 4 (IL-4) mRNA expression was significantly higher in caged hens. IL-10 mRNA expression was higher in the high-density C group than in the free range and low-density C groups. Supplementation with taurine decreased IL-10 mRNA expression significantly in the high-density group and increased superoxide dismutase (SOD) activity in the free range hens. We conclude that taurine has important protective effects against oviduct damage. Reducing housing density also results in less oxidative stress, less inflammatory cell infiltration, and lower levels of inflammatory mediators in the oviduct. Therefore, both dietary taurine and reduced housing density can ameliorate oviduct injury, enhance oviduct health, and promote egg production in laying hens.

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High molecular weight persimmon tannin ameliorates cognition deficits and attenuates oxidative damage in senescent mice induced by d-galactose

Cited by 64 publications

References 49 publications

Effects of taurine and housing density on renal function in laying hens

Effects of taurine and housing density on renal function in laying hens

Potential mechanisms of neurobehavioral disturbances in mice caused by sub-chronic exposure to low-dose VOCs

Influence of dietary taurine and housing density on oviduct function in laying hens

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