High mid-term revision rate after treatment of large, full-thickness cartilage lesions and OA in the patellofemoral joint using a large inlay resurfacing prosthesis: HemiCAP-Wave®

Laursen, Jens Ole

doi:10.1007/s00167-016-4352-2

Cited by 26 publications

(25 citation statements)

References 22 publications

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“…The patient had been out of work as a carpenter for almost 2 years and was at risk of losing his ability to work completely and becoming a heavy financial burden on society. We know from other studies [6,7,8,10] -that the loss of working ability can be fatal for such patients, who are still of working age, and the economic costs for society enormous, especially for these patients in the "Treatment Gap". In the US, 3.6 million patients with symptomatic knee-pain fall into this group [10].…”

Section: Resultsmentioning

confidence: 99%

“…The treatment of (osteo) Chondral lesions remains a clinical challenge. [1][2][3]6,7,8,16] A "gap" has been identified (9), where some patients with focal knee-lesions are considered too old for biological treatment or failed treatment, but too young for uni-or total arthroplasty (UKA/TKA). In order to fill this gap, an innovative, patient-specific metal implant (Episealer) has been designed from MRI-images and the lesion-size, and ongoing CPL (Controlled Product Launch) is taking Place, with almost 2-year follow-up.…”

Section: Objectivementioning

confidence: 99%

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3-Year Clinical Result of a Customized Metal Mini-Prosthesis for Focal Chondral Lesion in The Knee Of A Formerly Active 31-Year-Old Man.

Laursen¹

2017

JESO

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Section: Resultsmentioning

confidence: 99%

Section: Objectivementioning

confidence: 99%

3-Year Clinical Result of a Customized Metal Mini-Prosthesis for Focal Chondral Lesion in The Knee Of A Formerly Active 31-Year-Old Man.

Laursen¹

2017

JESO

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“…On the other hand, Laursen also showed a significant improvement in 2-year followup subjective scores, but the revision rate after 6 years was up to 28%. 20 This early failure rate seems rather unacceptable for a knee prosthesis such as the HemiCAP ® Wave prosthesis. Patel et al in another clinical trial with small number of patients (16 patients) demonstrated excellent early results with the HemiCAP ® Wave prosthesis.…”

Section: Resultsmentioning

confidence: 99%

The clinical outcome of the different HemiCAP and UniCAP knee implants: A systematic and comprehensive review

Malahias¹,

Chytas²,

Thorey³

2018

Orthop Rev (Pavia)

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The focal metallic cartilage resurfacing is a surgical method that offers an appropriate step between the biological techniques and arthroplasty in middle-aged patients with full-thickness cartilage defects. The advantages of this technique are that it addresses the defect, respects healthy tissues and provides stability and contoured surface similar to a full arthroplasty. A systematic review was conducted according to Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. Two reviewers (MM and DC) independently conducted the search using the MEDLINE/PubMed database and the Cochrane Database of Systematic Reviews (CDSR). These databases were searched for the terms hemicap knee implant and unicap knee implant and knee focal metallic implant. From the initial 21 studies that were evaluated, 10 were eligible for analysis. Considering both the HemiCAP focal implant and the HemiCap® Wave patellofemoral prosthesis, we found a lack of mid- to long-term clinical outcomes in well-designed prospective clinical studies. No Level I or II studies were found, while the limited number of patients who were included undermines the overall clinical results of these studies. The progression of osteoarthritis, the persisting pain and the subsequent high revision or failure rates in the limited available studies with long-term follow-up, seem to be the major drawbacks of these partial resurfacing techniques. Utilization of partial resurfacing for femoral or patellofemoral compartments results in good short-term outcome for middle-aged patients as a step between biological technique and total knee arthroplasty. The surgeon should be cognizant and also notify the patient of the high failure rates that are reported in the literature in mid- to longterm follow-up and ultimately, the decision to perform partial resurfacing should be taken by both the patient and the orthopedic surgeon.

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“…An arm with metal patches was considered, but it was decided that these were still experimental with insufficient data. A high revision rate was reported with the HemiCAP-Wave patch [ 39 ]. However, Becher and Cantillier [ 6 ] reviewed five other studies, wherein the revision rate was only about 10%.…”

Section: Discussionmentioning

confidence: 99%

The cost-effectiveness of osteochondral allograft transplantation in the knee

Mistry

Metcalfe

Smith

et al. 2019

Knee Surg Sports Traumatol Arthrosc

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Purpose Osteochondral allografts (OCA) consist of a layer of hyaline cartilage and a layer of underlying bone. They are used to repair combined defects of articular cartilage and bone. Such defects often occur in people far too young to have knee arthroplasty, for whom the main alternative to OCA is conservative symptomatic care, which will not prevent development of osteoarthritis. The aim of this report was to assess the cost-effectiveness of osteochondral allograft transplantation in the knee. Methods Systematic review of evidence on clinical effectiveness and economic modelling. Results The evidence on osteochondral allograft transplantation comes from observational studies, but often based on good quality prospective registries of all patients having such surgery. Without controlled trials, it was necessary to use historical cohorts to assess the effect of osteochondral grafts. There is good evidence that OCA are clinically effective with a high graft survival rate over 20 years. If an OCA graft fails, there is some evidence that revision with a second OCA is also effective, though less so than primary OCA. Economic modelling showed that osteochondral allograft transplantation was highly cost-effective, with costs per quality adjusted life year much lower than many other treatments considered cost effective. Conclusions Osteochondral allograft transplantation appears highly cost-effective though the cost per quality adjusted life year varies according to the widely varying costs of allografts. Based on one small study, revision OCA also appears very cost-effective, but more evidence is needed. Level of evidence II. Electronic supplementary material The online version of this article (10.1007/s00167-019-05392-8) contains supplementary material, which is available to authorized users.

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High mid-term revision rate after treatment of large, full-thickness cartilage lesions and OA in the patellofemoral joint using a large inlay resurfacing prosthesis: HemiCAP-Wave®

Abstract: IV.

Cited by 26 publications

References 22 publications

3-Year Clinical Result of a Customized Metal Mini-Prosthesis for Focal Chondral Lesion in The Knee Of A Formerly Active 31-Year-Old Man.

3-Year Clinical Result of a Customized Metal Mini-Prosthesis for Focal Chondral Lesion in The Knee Of A Formerly Active 31-Year-Old Man.

The clinical outcome of the different HemiCAP and UniCAP knee implants: A systematic and comprehensive review

The cost-effectiveness of osteochondral allograft transplantation in the knee

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