“…Since the introduction of hsTn assays has shifted the diagnosis of unstable angina (UA) in favor of non-ST elevation MI (NSTEMI), Herrero-Brocal et al performed a study to determine whether using hsTn results in medium-term prognostic differences in patients with these two conditions. While the medium-term incidence of major adverse cardiovascular events (MACE) was similar in patients with UA and NSTEMI, CV and all-cause mortality in NSTEMI patients was 2-fold higher than that of patients with UA [29] . In NSTEMI context, adequate risk assessment and subsequent clinical management are mandatory to optimize patient outcomes and the Global Registry of Acute Coronary Events (GRACE) risk score gives better risk evaluation than clinical judgment only in this setting.…”