High levels of Paleolithic Y-chromosome lineages characterize Serbia

Regueiro, María; Rivera, Luis; Damnjanovic, Tatjana; Lukovic, Ljiljana; Milašin, Jelena; Herrera, René J.

doi:10.1016/j.gene.2012.01.030

Cited by 20 publications

(18 citation statements)

References 45 publications

(98 reference statements)

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“…Our analyses revealed genetic distinctiveness between Slavs and populations of the Romance group (Italians and Romanians), Greeks, and Turks indicating rather limited gene flow between these groups despite their long‐term shared history throughout the duration of Roman, Byzantine, and Ottoman Empires. Nonetheless, the negligible genetic contribution of Turkish mtDNA gene pool to the Bulgarian population (Calafell et al, ) and to the patrilineal components of Serbian population (Regueiro et al, ) have already been observed.…”

Section: Discussionmentioning

confidence: 99%

“…Although south‐Slavic populations have been studied to date (Malyarchuk et al, ; Cvjetan et al, ; Pericic et al, ; Bosch et al, ; Zimmermann et al, ; Battaglia et al, ; Karachanak et al, ; Regueiro et al, ; Sarac et al, ), Serbian population is still genetically understudied at least at the mtDNA level which, to the best of our knowledge, has been surveyed by Cvjetan et al () and Zgonjanin et al () only. The knowledge on mtDNA variation in extant Serbian population is required for better understanding of their history and south‐Slavic identity in general.…”

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confidence: 99%

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Mitochondrial DNA perspective of Serbian genetic diversity

Davidović

Malyarchuk

Aleksić

et al. 2014

American J Phys Anthropol

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Although south-Slavic populations have been studied to date from various aspects, the population of Serbia, occupying the central part of the Balkan Peninsula, is still genetically understudied at least at the level of mitochondrial DNA (mtDNA) variation. We analyzed polymorphisms of the first and the second mtDNA hypervariable segments (HVS-I and HVS-II) and informative coding-region markers in 139 Serbians to shed more light on their mtDNA variability, and used available data on other Slavic and neighboring non-Slavic populations to assess their interrelations in a broader European context. The contemporary Serbian mtDNA profile is consistent with the general European maternal landscape having a substantial proportion of shared haplotypes with eastern, central, and southern European populations. Serbian population was characterized as an important link between easternmost and westernmost south-Slavic populations due to the observed lack of genetic differentiation with all other south-Slavic populations and its geographical positioning within the Balkan Peninsula. An increased heterogeneity of south Slavs, most likely mirroring turbulent demographic events within the Balkan Peninsula over time (i.e., frequent admixture and differential introgression of various gene pools), and a marked geographical stratification of Slavs to south-, east-, and west-Slavic groups, were also found. A phylogeographic analyses of 20 completely sequenced Serbian mitochondrial genomes revealed not only the presence of mtDNA lineages predominantly found within the Slavic gene pool (U4a2a*, U4a2a1, U4a2c, U4a2g, HV10), supporting a common Slavic origin, but also lineages that may have originated within the southern Europe (H5*, H5e1, H5a1v) and the Balkan Peninsula in particular (H6a2b and L2a1k).

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Mitochondrial DNA perspective of Serbian genetic diversity

Davidović

Malyarchuk

Aleksić

et al. 2014

American J Phys Anthropol

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“…Reference data include 32 populations from: North-Western Italy, South-Eastern Italy and Sicily (21, Boattini et al, 2013;Sarno et al, 2014), French Basques (3, Martínez-Cruz et al, 2012, Germany (3, Ręba"a et al, 2013), Poland and Slovakia (4, Ręba"a et al, 2013), Balkans (1, Regueiro et al, 2012). A full list is available in Supplementary Table S1 and their geographic position is represented in Supplementary Figure S1.…”

Section: Comparison Populationsmentioning

confidence: 99%

Traces of medieval migrations in a socially stratified population from Northern Italy. Evidence from uniparental markers and deep-rooted pedigrees

et al. 2014

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“…This shows that the approach of utilizing four haplogroup predictors to yield accurate and reliable prediction results will enable a proper comparison and analysis of the dataset of interest. Emmerova et al (2017) used 5 different predictors and based on 12 STRs 3 of the predictors assigned the haplogroups with 98% accuracy compared to SNP data used in the present study compared to Battaglia et al (2009) for the Bosnian and Croatian populations and Regueiro et al (2012) for the Serbian population can mainly be attributed to inaccuracies of haplogroup predictors in differentiating between the I haplogroup subclades (I1, I2a and I2b in this case).…”

Section: Discussionmentioning

confidence: 57%

A glance of genetic relations in the Balkan populations utilizing network analysis based on in silico assigned Y-DNA haplogroups

Šehović¹,

Zieger²,

Spahić³

et al. 2018

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The aim of this study is to provide an insight into Balkan populations' genetic relations utilizing in silico analysis of Y-STR haplotypes and performing haplogroup predictions together with network analysis of the same haplotypes for visualization of the relations between chosen haplotypes and Balkan populations in general. The population dataset used in this study was obtained using 23, 17, 12, 9 and 7 Y-STR loci for 13 populations. The 13 populations include: Bosnia and Herzegovina (B&H), . The overall dataset contains a total of 2179 samples with 1878 different haplotypes. I2a was detected as the major haplogroup in four out of thirteen analysed Balkan populations. The four populations (B&H, Croatia, Montenegro and Serbia) which had I2a as the most prevalent haplogroup were all from the former Yugoslavian republic. The remaining two major populations from former Yugoslavia, Macedonia and Slovenia, had E1b1b and R1a haplogroups as the most prevalent, respectively. The populations with E1b1b haplogroup as the most prevalent one are Macedonian, Romanian, as well as Albanian populations from Kosovo and Albania. The I2a haplogroup cluster is more compact when compared to E1b1b and R1b haplogroup clusters, indicating a larger degree of homogeneity within the haplotypes that belong to the I2a haplogroup. Our study demonstrates that a combination of haplogroup prediction and network analysis represents an effective approach to utilize publicly available Y-STR datasets for population genetics.

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High levels of Paleolithic Y-chromosome lineages characterize Serbia

Cited by 20 publications

References 45 publications

Mitochondrial DNA perspective of Serbian genetic diversity

Mitochondrial DNA perspective of Serbian genetic diversity

Traces of medieval migrations in a socially stratified population from Northern Italy. Evidence from uniparental markers and deep-rooted pedigrees

A glance of genetic relations in the Balkan populations utilizing network analysis based on in silico assigned Y-DNA haplogroups

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