High levels of N-terminal pro B-type natriuretic peptide are associated with ST resolution failure after reperfusion for acute myocardial infarction

Lorgis, Luc; Zeller, Marianne; Dentan, Gilles; Sicard, Pierre; Jolak, M.; L’Huillier, Isabelle; Vincent-Martin, Michel; Beer, Jean‐Claude; Makki, Hamid; Gambert, Philippe; Cottin, Yves

doi:10.1093/qjmed/hcm013

Cited by 12 publications

(7 citation statements)

References 29 publications

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“…[10][11][12][13][14] Sadanandan et al 15 reported that patients with BNP more than 80 pg/ml was associated with severity of coronary artery disease and multi -vessel disease as compare to patients with lower plasma BNP level. 16 L. Lorgis et al 16 This present study concluded that high BNP level is strongly associated with heart failure in patients presenting with STEMI.…”

Section: Discussionsupporting

confidence: 49%

Association of high BNP level with heart failure in patients presenting with STEMI.

Waqas¹,

Ilyas²,

Majeed³

et al. 2021

TPMJ

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Objective: The objective of this study is to to determine the association of high BNP level with heart failure in patients presenting with STEMI. Study Design: Cohort Study. Setting: Department of Cardiology, Punjab Institute of Cardiology, Lahore. Period: 01 January 2017 to 30 June 2017. Material & Methods: After meeting the inclusion criteria 150 patients were enrolled. Informed consent and demographic information was taken. Then patients divided in two groups, high and normal BNP groups. Then patients were admitted in cardiology wards and were followed-up there for 5 days. Patients evaluated for symptoms of heart failure and underwent echocardiography for confirmation of presence or absence of heart failure. All the collected data was entered and analyzed on SPSS version 21. Results: In this study the mean age high BNP group was 48.87± 10.18 years while the mean age in normal BNP group was 48.99±12.15 years. Male to female ratio of the patients was 2:1. The heart failure occurred in 19(12.67%) patients. There is 1.58 times higher risk of heart failure in high BNP than normal BNP i.e. RR=1.58[1.14-2.19]. Conclusion: This present study concluded that high BNP level is strongly associated with heart failure in patients presenting with STEMI.

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Section: Discussionsupporting

confidence: 49%

Association of high BNP level with heart failure in patients presenting with STEMI.

Waqas¹,

Ilyas²,

Majeed³

et al. 2021

TPMJ

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“…17,22 Elevated serum NT-proBNP levels on admission in patients with STEMI have been known as a predictor of cardiovascular mortality. 33,34 The NT-proBNP is also a reliable independent predictor of sudden cardiac death after MI. 35 Modulation of NT-proBNP is multifactorial, depending on left ventricular dysfunction, remodeling, left intraventricular pressure, and residual myocardial ischemia.…”

Section: Discussionmentioning

confidence: 99%

N-Terminal Pro-Brain Natriuretic Peptide Level is Associated With Severity and Complexity of Coronary Atherosclerosis in Patients With Acute Coronary Syndrome

Kurtul¹,

Yarlıoğlueş²,

Murat³

et al. 2014

Clin Appl Thromb Hemost

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N-terminal pro-brain natriuretic peptide (NT-proBNP) levels are associated with short- and long-term mortality in acute coronary syndrome (ACS). We investigated whether baseline NT-proBNP levels are associated with burden of coronary atherosclerosis assessed by SYNTAX score (SXScore). We enrolled 509 patients with ACS who underwent coronary angiography. The patients were divided into tertiles according to the SXScore: low SXScore (≤ 22), intermediate SXScore (23-32), and high SXScore (≥ 33). The NT-proBNP levels demonstrated an increase from low SXScore tertile to high SXScore tertile. The NT-proBNP levels according to the SXScore tertiles are as follows: low and intermediate (median 635 vs 1635, P = .014), low and high (median 635 vs 4568, P < .001), and intermediate and high (median 1635 vs 4568, P < .001). In multivariate analysis, NT-proBNP remained an independent predictor of high SXScore (odds ratio: 2.688, 95% confidence interval: 1.315-5.494, P = .007) together with age (P = .002), neutrophil-lymphocyte ratio (P = .017), and presence of non-ST-segment elevation ACS (P = .002). The NT-proBNP was independently associated with burden of coronary atherosclerosis in patients with ACS.

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“…[7] не получили различий по ТИМ у больных РА с нормальным и повышенным уровнем NT-proBNP, что, вероятно, связано с низкой активностью РА. С другой стороны, имеются данные о взаимосвязи уровня NT-proBNP и распространенности коронарного атеросклероза при остром коронарном синдроме, а не только тяжести ХСН [29]. В некоторых исследованиях указывается на выделение NT-proBNP эндотелием сосудов, что может объяснить зависимость его концентрации от тяжести атеросклероза [30].…”

Section: зависимость чувствительности и специфичности уровня Nt-probnunclassified

N-terminal pro-brain natriuretic peptide levels and diastolic dysfunction in patients with early rheumatoid arthritis before the administration of disease-modifying antirheumatic drugs

Kirillova¹,

Новикова²,

Попкова³

et al. 2016

Ter. arkh.

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Just at the early disease stage, the patients are noted to have a high NT-proBNP level that is influenced by higher BMI, low LDL levels, CAA, CHF, and high CRP values. In the patients with early RA, the diagnostically significant NT-proBNP concentration for CHF detection was higher (237 pg/ml) than in those without RA (125 pg/ml). The patients with early RA should undergo NT-proBNP determination, LVDD screening, correction of TRF for CVD, atherosclerosis treatment, and remission achievement.

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High levels of N-terminal pro B-type natriuretic peptide are associated with ST resolution failure after reperfusion for acute myocardial infarction

Abstract: Our data show a strong association between high levels of Nt-proBNP at admission and incomplete STR, suggesting that Nt-proBNP may be useful for early risk stratification in reperfusion therapy after acute myocardial infarction.

Cited by 12 publications

References 29 publications

Association of high BNP level with heart failure in patients presenting with STEMI.

Association of high BNP level with heart failure in patients presenting with STEMI.

N-Terminal Pro-Brain Natriuretic Peptide Level is Associated With Severity and Complexity of Coronary Atherosclerosis in Patients With Acute Coronary Syndrome

N-terminal pro-brain natriuretic peptide levels and diastolic dysfunction in patients with early rheumatoid arthritis before the administration of disease-modifying antirheumatic drugs

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