High-intensity strength training improves quality of life in cancer survivors

Backer, Ingrid C. De; Breda, Eric van; Vreugdenhil, Art; Nijziel, Marten R.; Kester, A.D.M.; Schep, Goof

doi:10.1080/02841860701418838

Cited by 80 publications

(87 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The tolerance and effects noted immediately post-rehabilitation have already been published (De Backer et al, 2007b). After completion of the programme, repeated testing showed a continuation and stabilisation of the muscle strength level ( Figure 2) and peak VO 2 .…”

Section: Discussionmentioning

confidence: 92%

“…As a consequence, resistance training seems to be the programme of choice for regaining muscle strength and, in this way, improving activities of daily living and HRQOL (Brill et al, 2000). In addition, in cancer patients, muscle strength is related to quality-of-life aspects with correlations ranging from 0.47 to 0.75 (De Backer et al, 2007b).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Long-term follow-up after cancer rehabilitation using high-intensity resistance training: persistent improvement of physical performance and quality of life

et al. 2008

View full text Add to dashboard Cite

The short-term beneficial effects of physical rehabilitation programmes after cancer treatment have been described. However, little is known regarding the long-term effects. The purpose of this study was to investigate the long-term effects of high-intensity resistance training compared with traditional recovery. A total of 68 cancer survivors who completed an 18-week resistance training programme were followed for 1 year. During the 1-year follow-up, 19 patients dropped out (14 due to recurrence of cancer). The remaining 49 patients of the intervention group were compared with a group of 22 patients treated with chemotherapy in the same period but not participating in any rehabilitation programme. Outcome measures were muscle strength, cardiopulmonary function, fatigue, and health-related quality of life. One year after completion of the rehabilitation programme, the outcome measures in the intervention group were still at the same level as immediately after rehabilitation. Muscle strength at 1 year was significantly higher in patients who completed the resistance training programme than in the comparison group. High-intensity resistance training has persistent effects on muscle strength, cardiopulmonary function, quality of life, and fatigue. Rehabilitation programmes for patients treated with chemotherapy with a curative intention should include high-intensity resistance training in their programme.

show abstract

Section: Discussionmentioning

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Long-term follow-up after cancer rehabilitation using high-intensity resistance training: persistent improvement of physical performance and quality of life

et al. 2008

View full text Add to dashboard Cite

show abstract

“…High intensity training combined with supplemental whey proteins within one hour after training is recommended to achieve the ultimate improvement in functional capacity in a short time span of four weeks [9,12]. Nutritional supplementation four weeks before and after surgery has been shown to enhance preoperative functional walking capacity and recovery in patients undergoing colorectal resection for cancer [12].…”

Section: Discussionmentioning

confidence: 99%

“…Poor physical performance capacity increases the risk of complications after major non-cardiac surgery and prolongs recovery after abdominal surgery [7]. The role of nutritional status and psychological wellbeing in surgical recovery may also not be underestimated and might be improved accordingly [8,9]. Standard consultation of a dietician and psychologist may enhance patients' preoperative status by improving their oral intake, offering nutritional supplements (i.e., multi vitamins, proteins) and strategies to cope with anxiety.…”

mentioning

confidence: 99%

Preoperative modifiable risk factors in colorectal surgery: an observational cohort study identifying the possible value of prehabilitation

et al. 2017

View full text Add to dashboard Cite

Surgery is the most common therapeutic intervention, and associated with 20-40% reduction in physiological and functional capacity. Postoperative complications occur in up to 50% of patients resulting in higher mortality rates and greater hospital costs. The number and severity of complications is closely related to patients' preoperative performance status. The aim of this study was to identify the most important preoperative modifiable risk factors that could be part of a multimodal prehabilitation program. Methods: Prospectively collected data of a consecutive series of Dutch CRC patients undergoing colorectal surgery were analyzed. Modifiable risk factors were correlated to the Comprehensive Complication Index (CCI) and compared within two groups: none or mild complications (CCI <20), and severe complications (CCI 20). Multivariate logistic regression analysis was done to explore the combined effect of individual risk factors. Results: In this 139 patient cohort, smoking, malnutrition, alcohol consumption, neoadjuvant therapy, higher age, and male sex, were seen more frequently in the severe complications group (CCI 20). Patients with severe complications had significantly longer hospital stay (16 vs. 6 days, p < 0.001). The risk for severe complications was increased in patients with ASA score III [adjusted odds ratio (OR) 4.4, 95% CI 1.04-18.6], and hemoglobin level <7 mmol/l (adjusted OR 3.3, 95% CI 1.3-8.2). Compared to having no risk factors, more than one risk factor increased OR of severe complications (crude OR 5.2, 95% CI 1.8-15). Conclusion: This study revealed that the risk of getting severe complications increases with the number of risk factors present preoperatively. Several preoperative patient-related risk factors are modifiable. Multimodal prehabilitation may improve patients' preoperative status and should be tested in a multicenter randomized controlled trial. With an international consortium (Copenhagen, Montreal, Paris, Eindhoven) we initiated a randomized controlled trial (NTR5947).

show abstract

“…The current exercise programme had been studied among patients with other cancer types (De Backer et al., 2007, 2008) and the intensity of the interval training was prescribed based on the patients’ individual fitness level assessed by the steep ramp test. As the training load was reduced in at least some of the training sessions in about half of the patients, the programme might have been too challenging and/or the steep ramp test might have been not accurate enough in estimating the correct training load in this patient population.…”

Section: Discussionmentioning

confidence: 99%

Lessons learnt from a process evaluation of an exercise intervention in patients treated with autologous stem cell transplantation

Persoon

Chinapaw²,

Buffart

et al. 2017

Eur J Cancer Care

View full text Add to dashboard Cite

This paper describes the process evaluation of an 18‐week supervised exercise programme in 50 patients treated with high‐dose chemotherapy followed by autologous stem cell transplantation. The intervention included 30 exercise sessions with six resistance exercises and interval training. We evaluated the context, dose delivered and received, and patients’ and physiotherapists’ satisfaction with the intervention.Ninety‐two per cent of the patients trained within 15 km of their home address, with an average session attendance of 86%. Most patients trained at the prescribed intensity for four of the six resistance exercises, but the dose delivered and received of the two remaining resistance exercises and interval training could not be determined. Both patients and physiotherapists highly appreciated the programme (score of 8.3 and 7.9 out of 10 respectively). This process evaluation provided valuable lessons for future trials: (1) It is possible to deliver supervised exercise training to this patient group in local physiotherapy practices; (2) to determine dose received all intervention components should be standardised; and (3) to optimise data collection, all study materials should be tested more extensively prior to the start of the intervention.

show abstract

High-intensity strength training improves quality of life in cancer survivors

Abstract: We conclude that a supervised, high-intensity strength training program seems to be an effective means to improve muscle strength, cardiopulmonary function, and HRQOL and should be incorporated in cancer rehabilitation programs. Further randomized trials are needed to confirm the results.

Cited by 80 publications

References 42 publications

Long-term follow-up after cancer rehabilitation using high-intensity resistance training: persistent improvement of physical performance and quality of life

Long-term follow-up after cancer rehabilitation using high-intensity resistance training: persistent improvement of physical performance and quality of life

Preoperative modifiable risk factors in colorectal surgery: an observational cohort study identifying the possible value of prehabilitation

Lessons learnt from a process evaluation of an exercise intervention in patients treated with autologous stem cell transplantation

Contact Info

Product

Resources

About