High intensity physical exercise induced effects on plasma levels of copper and zinc

Abstract

Physical exercise leads to many metabolic, cardiovascular, and muscular changes in the body. The trace elements (TE) zinc and copper are directly involved, as enzymatic cofactors, in many of these processes, especially those related to nutrients metabolism, oxygen transport, and formation of usable energy. The effects of high-intensity physical exercise on plasma levels of CU2+ and Zn2+ in 19 subjects are investigated (9 males and 10 females). Plasma copper concentration decreases, and plasma zinc concentration increases, after exercise, in both sexes. After 30 min recovery, both TE concentration values shifts toward rest values in both sexes. These results only partially agree with literature data, probably because we used the treadmill exercise, which makes many muscles work, whereas other authors made their subjects perform a cycloergometer exercise. Physical exercise causes a marked redistribution of TE (copper and zinc) between body stores, bloodstream, and tissues. The condition of high metabolism may lead to a deficiency of TE, requiring supplementation in order to maintain high level performance.

Serum Levels of Cu, Se, and Zn in Adult Rural/Urban Residents in Ghana: Paradigm Shift?

“…Furthermore, urban dwellers are more active than rural dwellers, and some authors have demonstrated that physical exercise produces redistribution and changes of trace elements such as Cu in human blood and tissue [48,49]. Additionally, some authors have found a higher loss of minerals such as Cu through sweat in athletes with respect to the general population [50,51]. Activity may therefore explain the differences in Cu levels between the two groups.…”

Effect of zinc supplementation on lipid peroxidation and lactate levels in rats with diabetes induced by streptozotocin and subjected to acute swimming exercise

“…Acute exercise (45,46) and diabetes (3,44) were found to show a marked increase in zinc-supplemented diabetic groups (groups 3 and 6), relative to groups 4, 7 and 8, indicates the importance of zinc supplementation in association with exercise and diabetes. Several researchers showed that serum zinc values decreased after exercise (45,46,47). Elevated levels of zinc we found in zinc-supplemented swimming group (group 5) point out the signifi cance of zinc supplementation in association with exercise.…”

“…It was argued that daily and regular exercise could be responsible for the impairment in zinc metabolism and that impairments in zinc metabolism as well as zinc loss could lead to muscle exhaustion and weakness (45). Bordin et al (46) demonstrated that physical exercise led to re-distribution of zinc among body stores, blood and tissues, and the increased metabolism caused zinc defi ciency. Lower serum zinc levels that were found in group 4 subjected to acute swimming exercise, are consistent with literature data.…”

Aspectos sobre a relação entre exercício físico, estresse oxidativo e zinco

“…Ainda em 1993, Bordin et al 45 encontraram aumento nas concentrações de zinco plasmático logo após o exercício intenso.…”

“…Tuya et al 12 Peake et al 41 Singh et al 42 Van Loan et al 43 Oliveira et al 44 Bordin et al 45 Anderson et al 46 Margaritis et al 38 Inal et al 39 Oliveira et al 44 Fiamocini 50 Koury et al 52 Ørtenbland et al 53 Brites et al 54 Koury et al 54 Oliveira et al 59 Ali et al 60 Brilla et al 61 VanLoan et al Em outro estudo realizado com jogadores de futebol, foi observada diferença estatística (p<0,001) na potência dos músculos do grupo suplementado com zinco, quando comparada com a do grupo-controle 61 . Concomitante a esse estudo, VanLoan et al 62 verificaram em sua pesquisa relação inversa entre a depleção aguda de zinco e a capacidade de trabalho musculoesquelético.…”