High-intensity light-emitting diode<i>vs</i>fluorescent tubes for intensive phototherapy in neonates

Sherbiny, Hanan S.; Youssef, Doaa Mohammed; Sherbini, Ahmad S; Elbehedy, Rabab M.; Sherief, Laila M.

doi:10.1080/20469047.2015.1109239

Cited by 2 publications

(12 citation statements)

References 21 publications

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“…Seven studies took measures to keep the irradiance similar in the study groups, 3 15 23 24 32 33 37 while two studies kept the distance between the light source and the infant similar. 25 26 27 28 29 31 34 35 36 38…”

Section: Resultsmentioning

confidence: 99%

“…We evaluated 41 full-text articles to check for eligibility, and, ultimately, 21 were included in this review. 3 15 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 The ﬂowchart for evidence search and study selection is shown in Fig. 1 .…”

Section: Resultsmentioning

confidence: 99%

“…15 23 24 25 Fifteen articles compared LED devices with fluorescent lights. 3 26 27 28 29 31 32 33 34 35 36 37 38 40 41 Two studies compared LED devices with halogen and fluorescent lights. 30 39 Five studies enrolled only full-term neonates 15 23 38 40 41 and 13 studies included infants over 35 or 36 weeks of gestation.…”

Section: Resultsmentioning

confidence: 99%

“…Two studies 24 34 used super LED phototherapy with a different physical and chemical composition (indium gallium nitrate) that emits a high-intensity blue light with a maximum peak at 450 nm, and a new structured device with many LEDs in a small capsule, conferred significantly higher potency compared with those using gallium nitrate alone. Using LED phototherapy very close to the skin of the infant, as an under-the-body-device 34 or embedded in a blanket 39 a significant improvement in the efficacy of phototherapy was reported.…”

Section: Discussionmentioning

confidence: 99%

“…Conventional phototherapy units are associated with hyperthermia and skin rash probably produced by infrared and ultraviolet rays. 34 Therefore, strict monitoring of the distance of these devices and the level of irradiance is recommended.…”

Section: Discussionmentioning

confidence: 99%

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Light-Emitting Diode (LED) Phototherapy versus Non-LED Phototherapy Devices for Hyperbilirubinemia in Neonates: A Systematic Review and Meta-analysis

2022

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Objective: This review was conducted to evaluate the efficacy of light-emitting diode (LED) phototherapy as compared to the conventional phototherapy in neonates with unconjugated hyperbilirubinemia and their adverse effects. Study Design: We searched the following databases right from their inception till April, 2021: MEDLINE, EMBASE, Cochrane Library, and LILACS. Randomized clinical trials (RCTs) comparing the LED phototherapy with other light sources, which enrolled newborns (term and preterm) with unconjugated hyperbilirubinemia were included. Results: We included 21 articles in this review. The treatment with the LED light therapy had a lower failure rate as compared to the non-LED one (RR 0.60, 95% CI 0.39 to 0.94). The mean duration of phototherapy was significantly shorter in the group with the LED light source as compared to the one with the non-LED light source (mean difference (hours) −8.07, 95% CI −8.45 to −7.68), regardless of the type of non-LED units. However, the rate of bilirubin showed a comparable decline (mean difference (mg/dL/hour) 0.01, 95% CI −0.00, 0.03) in both the light sources, irrespective of irradiance or distance. No studies reported primary outcomes related to the neurotoxicity effects of hyperbilirubinemia in neonates. The LED light devices caused a significantly higher risk of hypothermia. Neonates were at a lower risk of developing hyperthermia and skin rash with the LED light therapy. Conclusion: Our findings provide support for the use of LED light source phototherapy due to its better clinical efficacy, which is evidenced by its shorter duration and lower rate of treatment failure, as compared to the non-LED light sources.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Light-Emitting Diode (LED) Phototherapy versus Non-LED Phototherapy Devices for Hyperbilirubinemia in Neonates: A Systematic Review and Meta-analysis

2022

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Effectiveness of light emitting diode phototherapy for direct coombs positive newborns

Okur

Büyüktiryaki

Uraş

et al. 2019

Harran Üniversitesi Tıp Fakültesi Dergisi

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Background: Phototherapy is the most frequently used treatment when serum bilirubin levels exceed physiological limits. The direct antiglobulin titer (DAT) test is regarded as the cornerstone of diagnosis of immune hemolytic disease of the newborn. Methods: Patients with hyperbilirubinemia who were born in our hospital and whose gestational age was over 35 weeks were enrolled. DAT positive and DAT negative patients were compared in terms of light emitting diode (LED) phototherapy efficacy. Results: Seventy-seven cases were DAT-negative and 72 were DAT-positive. No statistically significant differences were found for the duration of phototherapy and hospitalization between the DAT-positive and negative groups. In the DAT-positive group, the phototherapy needs of the patients were determined to occur at an earlier stage (postnatal age 1.4 day, p<0.05), and the rate of patients requiring exchange transfusion, blood transfusion and intravenous immunoglobulin was found to be statistically significant higher in DAT-positive infants. Conclusions: Although LED phototherapy is effective in DAT-positive patients, the need for exchange transfusion and intravenöz immunoglobulin (IVIG) shows that there is still a need for more effective phototherapy in these patients.

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High-intensity light-emitting diodevsfluorescent tubes for intensive phototherapy in neonates

Abstract: Super LED is a safe rescue treatment for severe neonatal hyperbilirubinaemia, and its implementation may reduce the need for exchange transfusion.

Cited by 2 publications

References 21 publications

Light-Emitting Diode (LED) Phototherapy versus Non-LED Phototherapy Devices for Hyperbilirubinemia in Neonates: A Systematic Review and Meta-analysis

Light-Emitting Diode (LED) Phototherapy versus Non-LED Phototherapy Devices for Hyperbilirubinemia in Neonates: A Systematic Review and Meta-analysis

Effectiveness of light emitting diode phototherapy for direct coombs positive newborns

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