High-Intensity Interval Training Versus Moderate-Intensity Continuous Training in Middle-Aged and Older Patients with Type 2 Diabetes: A Randomized Controlled Crossover Trial of the Acute Effects of Treadmill Walking on Glycemic Control

Mendes, Romeu; Sousa, Nélson; Themudo-Barata, José Luís; Reis, Víctor Machado

doi:10.3390/ijerph16214163

Cited by 39 publications

(28 citation statements)

References 61 publications

(107 reference statements)

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“…The study also showed that resistance exercise improves glycemic control, 97,104,[114][115][116][117][118][119][120][121][122][123][124][125][126][127][128][129][130] insulin sensitivity, 105,106,114,115,117,129 insulin responsiveness, 116 insulin action, 70 physical functions, 131 and cardiopulmonary fitness, 132 decreases insulin resistance, 97 abdominal fat, 114 BMI, 132 insulin levels, 118,132,133 triacylglycerol levels, 118 lipid profile, 97,105 body fat, 132 HbA1c levels, 119,132,133 BP, 97 and cardiovascular risk, 106 and increases GLUT-4 translocation in skeletal muscle, 117 and strength 119,120,…”

Section: Management Of T2dmmentioning

confidence: 99%

<p>Antidiabetic Effects of Physical Activity: How It Helps to Control Type 2 Diabetes</p>

Wake¹

2020

DMSO

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Despite the improvements in clinical care of the patients, research updates, and public health interventions, there is still an increase in the prevalence, incidence, and mortality because of diabetes mellitus (DM). DM is a public health problem in both developed and developing countries. It has increased alarmingly, putting this disease in the dimension of an epidemic. Diabetes is associated with several complications which increase the risk of many serious health problems on the other side. Therefore, this review was aimed to discuss the antidiabetic effects of physical activity (PA) on type 2 DM (T2DM) by summarizing the significant studies on this topic. This review found that several studies have recommended the utilization of PA for the effective management of T2DM. PA is a non-pharmacologic therapy which is a significant strategy for the management of T2DM and is an appropriate lifestyle modification approach to be practiced by these patients. The studies showed that PA has antidiabetic effects which are evidenced by its substantial role in improving the blood glucose (BG) levels of the individuals with T2DM where it helps them to control their levels of glucose in the blood. It plays a significant role in glycemic control of this disease by lowering the BG levels through possible mechanisms such as decreasing insulin resistance, increasing production of glucose transporter type 4 (GLUT-4), lowering visceral adipose tissue (VAT), increasing pancreatic β-cell functions, using glucose for energy, and so on. In turn, the controlled glycemia helps to prevent the complications associated with uncontrolled T2DM and this would further improve the overall health of the patients and the burden on the health professionals as well. Finally, this review concludes that PA is the cornerstone in the management of T2DM. It also suggests that more attention is needed to its significance in the prevention, glycemic control, and its role in the management of the morbidity and mortality associated with T2DM. Practical PA recommendations and suggestions for the future direction of research in this area are also provided.

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Section: Management Of T2dmmentioning

confidence: 99%

<p>Antidiabetic Effects of Physical Activity: How It Helps to Control Type 2 Diabetes</p>

Wake¹

2020

DMSO

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“…our study with 12⋅7 ± 0⋅8 points). Higher exercise intensities result in greater acute and chronic glycaemic control in T2D patients 30 – 32 . The fact that this exercise programme includes both aerobic and resistance exercise seems crucial for inducing benefits since isolated aerobic or resistance exercise effects on HbA1c are less pronounced than combined aerobic and resistance exercise 33 .…”

Section: Discussionmentioning

confidence: 99%

Benefits of adding food education sessions to an exercise programme on cardiovascular risk factors in patients with type 2 diabetes

et al. 2021

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To evaluate the impact of adding food education sessions to an exercise programme on cardiovascular risk factors in middle-aged and older patients with type 2 diabetes (T2D), a randomised parallel-group study was performed. Glycated haemoglobin, body mass index (BMI), waist circumference, fat mass (FM) and blood pressure were assessed at baseline and after 9 months. The recruitment was made in three primary healthcare centres from Vila Real, Portugal. Thirty-three patients (65⋅4 ± 5⋅9 years old) were engaged in a 9-month community-based lifestyle intervention programme: a supervised exercise programme (EX; n = 15; combined aerobic, resistance, agility/balance and flexibility exercise; three sessions per week; 75 min per session); or the same exercise programme plus concomitant food education sessions (EXFE; n = 18; 15-min lectures and dual-task strategies during exercise (answer nutrition questions while walking); 16 weeks). Significant differences between groups were identified in the evolution of BMI (P < 0.001, $\eta _{\rm p}^2 = 0{\cdot} 150$ ) and FM (P < 0.001, $\eta _{\rm p}^2 = 0{\cdot}130$ ), with best improvements observed in the EXFE group. The addition of a simple food education dietary intervention to an exercise programme improved body weight and composition, but not glycaemic control and blood pressure in middle-aged and older patients with T2D.

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“…HIIT volume is usually 90% lower than what is commonly used at endurance training, and also the time spent to perform the entire HIIT session is, often, 75% shorter [ 100 ]. Mendes et al recently compared the acute effects of HIIT versus moderate-intensity continuous training (MICT) on glycemic control in middle-aged and older patients with T2DM [ 101 ]. Fifteen patients with T2DM, who were volunteers to participate of the study (60.25 ± 3.14 years; glycated hemoglobin 7.03 ± 0.33%; medicated with metformin and/or gliptins), were inserted into a randomized controlled crossover trial.…”

Section: Exercise In T2dm: Types Variables and Outcomesmentioning

confidence: 99%

Exercise–Linked Irisin: Consequences on Mental and Cardiovascular Health in Type 2 Diabetes

Sousa

Improta-Caria

Souza

2021

IJMS

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Type 2 diabetes mellitus (T2DM) is a metabolic disorder associated with insulin resistance and hyperglycemia. Chronic exposure to a T2DM microenvironment with hyperglycemia, hyperinsulinemia, oxidative stress and increased levels of proinflammatory mediators, has negative consequences to the cardiovascular system and mental health. Therefore, atherosclerotic cardiovascular diseases (CVD) and mental health issues have been strongly associated with T2DM. Lifestyle modifications, including physical exercise training, are necessary to prevent T2DM development and its associated complications. It is widely known that the regular practice of exercise provides several physiological benefits to subjects with T2DM, such as managing glycemic and blood pressure levels. Different types of exercise, from aerobic to resistance training, are effective to improve mental health and cognitive function in T2DM. Irisin is a myokine produced in response to exercise, which has been pointed as a relevant mechanism of action to explain the benefits of exercise on cardiovascular and mental health in T2DM patients. Here, we review emerging clinical and experimental evidence about exercise-linked irisin consequences to cardiovascular and mental health in T2DM.

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High-Intensity Interval Training Versus Moderate-Intensity Continuous Training in Middle-Aged and Older Patients with Type 2 Diabetes: A Randomized Controlled Crossover Trial of the Acute Effects of Treadmill Walking on Glycemic Control

Cited by 39 publications

References 61 publications

<p>Antidiabetic Effects of Physical Activity: How It Helps to Control Type 2 Diabetes</p>

<p>Antidiabetic Effects of Physical Activity: How It Helps to Control Type 2 Diabetes</p>

Benefits of adding food education sessions to an exercise programme on cardiovascular risk factors in patients with type 2 diabetes

Exercise–Linked Irisin: Consequences on Mental and Cardiovascular Health in Type 2 Diabetes

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