“High-intensity interval training may reduce in-stent restenosis following percutaneous coronary intervention with stent implantation: A randomized controlled trial evaluating the relationship to endothelial function and inflammation.” Am Heart J 2009;158:734-41

Meyer, Philippe; Gayda, Mathieu; Normandin, Éve; Guiraud, Thibaut; Juneau, Martin; Nigam, Anil

doi:10.1016/j.ahj.2009.12.018

Cited by 5 publications

(5 citation statements)

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“…Although as effective or even superior to CAET (see the Section 3.1), these HIIT protocols may have some limitations and most importantly were chosen arbitrarily [22,34]. Indeed, our previous work demonstrated that longerstage HIIT protocols with active recovery had higher mean intensity (% VȮ 2 peak ), were less tolerated (higher RPE) and were associated with lower exercise session compliance for CHD patients [22,23,25].…”

Section: Hiit With Medium To Long Intervalsmentioning

confidence: 96%

High-intensity interval training in patients with coronary heart disease: Prescription models and perspectives

Ribeiro

Boidin

Juneau

et al. 2017

Annals of Physical and Rehabilitation Medicine

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Recently, high-intensity interval training (HIIT) has emerged as an alternative and/or complementary exercise modality to continuous aerobic exercise training (CAET) in CHD patients. However, the literature contains descriptions of many HIIT protocols with different stage durations, nature of recovery and intensities. In this review, we discuss the most recent forms of validated HIIT protocols in patients with coronary heart disease (CHD) and how to prescribe and use them during short- and long-term (phase II and III) cardiac rehabilitation programs. We also compare the superior and/or equivalent short- and long-term effects of HIIT versus CAET on aerobic fitness, cardiovascular function, and quality of life; their efficiency, safety, and tolerance; and exercise adherence. Short interval HIIT was found beneficial for CHD patients with lower aerobic fitness and would ideally be used in initiation and improvement stages. Medium and/or long interval HIIT protocols may be beneficial for CHD patients with higher aerobic fitness, and would be ideally used in the improvement and maintenance stages because of their high physiological stimulus. Finally, we propose progressive individualized models of HIIT programs (phase II to III) for patients with CHD and how to ideally use them according to the clinical status of patients and phase of the cardiac rehabilitation program.

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Section: Hiit With Medium To Long Intervalsmentioning

confidence: 96%

High-intensity interval training in patients with coronary heart disease: Prescription models and perspectives

Ribeiro

Boidin

Juneau

et al. 2017

Annals of Physical and Rehabilitation Medicine

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“…Even if high-risk patients with severe coronary artery disease or heart failure could benefit the most from more intensive exercise training like high-intensity interval training, its safety has not been properly established. 130 For example, exercise intensity might be a critical factor for the development of exercise-induced hypertension. Increased exercise intensity could trigger more endothelial responses in the absence of inflammatory markers.…”

Section: Immune-regulating Effects Of Exercise Trainingmentioning

confidence: 99%

Immune-regulating effects of exercise on cigarette smoke-induced inflammation

Madani¹,

Alack²,

Richter³

et al. 2018

JIR

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Long-term cigarette smoking (LTCS) represents an important risk factor for cardiac infarction and stroke and the central risk factor for the development of a bronchial carcinoma, smoking-associated interstitial lung fibrosis, and chronic obstructive pulmonary disease. The pathophysiologic development of these diseases is suggested to be promoted by chronic and progressive inflammation. Cigarette smoking induces repetitive inflammatory insults followed by a chronic and progressive activation of the immune system. In the pulmonary system of cigarette smokers, oxidative stress, cellular damage, and a chronic activation of pattern recognition receptors are described which are followed by the translocation of the NF-kB, the release of pro-inflammatory cytokines, chemokines, matrix metalloproteases, and damage-associated molecular patterns. In parallel, smoke pollutants cross directly through the alveolus–capillary interface and spread through the systemic bloodstream targeting different organs. Consequently, LTCS induces a systemic low-grade inflammation and increased oxidative stress in the vascular system. In blood, these processes promote an increased coagulation and endothelial dysfunction. In muscle tissue, inflammatory processes activate catabolic signaling pathways followed by muscle wasting and sarcopenia. In brain, several characteristics of neuroinflammation were described. Regular exercise training has been shown to be an effective nonpharmacological treatment strategy in smoke-induced pulmonary diseases. It is well established that exercise training exerts immune-regulating effects by activating anti-inflammatory signaling pathways. In this regard, the release of myokines from contracting skeletal muscle, the elevations of cortisol and adrenalin, the reduced expression of Toll-like receptors, and the increased mobilization of immune-regulating leukocyte subtypes might be of vital importance. Exercise training also increases the local and systemic antioxidative capacity and several compensatory mechanisms in tissues such as an increased anabolic signaling in muscle or an increased compliance of the vascular system. Accordingly, regular exercise training seems to protect long-term smokers against some important negative local and systemic consequences of smoking. Data suggest that it seems to be important to start exercise training as early as possible.

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“…Interval training has been proven to be more effective than MICE in improving both in healthy (9,15) and CHD patients (23,33). Despite this fact, the acute cardiovascular responses of coronary patients to HIIE have not been studied in detail; this information is required for safety and efficacy reasons before considering the use of HIIE in cardiac rehabilitation programs (18). We recently compared the physiological responses of 20 coronary patients to four different single sessions of HIIE which varied in exercise phase duration (15 s or 60 s) and type of recovery (active or passive) (13) .…”

Section: Paragraph #mentioning

confidence: 99%