2008
DOI: 10.3348/kjr.2008.9.4.291
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High-Intensity Focused Ultrasound Therapy: an Overview for Radiologists

Abstract: High-intensity focused ultrasound therapy is a novel, emerging, therapeutic modality that uses ultrasound waves, propagated through tissue media, as carriers of energy. This completely non-invasive technology has great potential for tumor ablation as well as hemostasis, thrombolysis and targeted drug/gene delivery. However, the application of this technology still has many drawbacks. It is expected that current obstacles to implementation will be resolved in the near future. In this review, we provide an overv… Show more

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Cited by 156 publications
(131 citation statements)
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References 63 publications
(84 reference statements)
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“…Many collateral injuries have been reported due to scattered and reflected high-intensity ultrasound waves, such as skin burns, peripheral nerve damage, and bowel injury. 21,22 Great care also needs to be taken in areas that are subject to respiratory movement, because of a lack of precision, or the presence of sonic shadowing due to overlying bony substances. 21 In such situations it may be necessary for the anaesthetist to use controlled ventilation.…”
Section: Limitations Of High-intensity Focused Ultrasoundmentioning
confidence: 99%
“…Many collateral injuries have been reported due to scattered and reflected high-intensity ultrasound waves, such as skin burns, peripheral nerve damage, and bowel injury. 21,22 Great care also needs to be taken in areas that are subject to respiratory movement, because of a lack of precision, or the presence of sonic shadowing due to overlying bony substances. 21 In such situations it may be necessary for the anaesthetist to use controlled ventilation.…”
Section: Limitations Of High-intensity Focused Ultrasoundmentioning
confidence: 99%
“…HIFU has the advantage of being non-invasive. However, several complications are reported: skin and/or subcutaneous edema, pain, skin burns, infection of the procedure site, and injury to the adjacent organs [2][3][4][5]. Higher attenuation of the HIFU beams increases the risk of damage in the ribs and overlying tissues, including the skin in the path of the beam.…”
Section: Introductionmentioning
confidence: 99%
“…Sonic waves (extracorporeal shock wave lithotripsy) can be used for destruction of kidney stones (Gallucci et al, 2001). Other applications include focused ultrasound surgery (FUS), thrombolysis and hemostasis (Kim et al, 2008;Vaezy et al, 2001). Burgess et al (2007) reported HIFU for hemostasis in the posterior liver of 17 pigs.…”
Section: Ultrasoundmentioning
confidence: 99%